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Dr. Muftuler edits book on using MRI to quantify morphology and physiology of the human body

June 27, 2013 College News -L. Tugan Muftuler, PhD, Associate Professor of Neurosurgery, edited Quantifying Morphology and Physiology of the Human Body Using MRI, which was published in May by Taylor & Francis.

The book presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems. The book is meant to be a reference for readers who want to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms.

Each chapter offers information on data acquisition, processing, and analysis techniques as well as clinical applications. The text organizes the techniques based on their primary use either in the brain or the body. Some of the techniques, such as diffusion-weighted imaging and diffusion tensor imaging, span several application areas, including brain imaging, cancer imaging, and musculoskeletal imaging. The book also covers up-and-coming quantitative techniques that explore tissue properties other than the presence of protons (or other MRI-observable nuclei) and their interactions with their environment.

Dr Muftuler’s research focuses on the development of new hardware and imaging techniques to better study the changes of various diseases with diagnostic imaging.

His current projects include:

  • Imaging studies of neuroanatomy and function
     
  • Studies of aging and dementia to diagnose the disease at early stages
     
  • Studies of brain development to study changes in pre-adolescent development
     
  • Imaging of spinal degeneration to explore what leads to this ailment
     
  • MR based electrical impedance tomography (MREIT) This technique has been used to study changes in animal models of breast cancer.
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