Research Collaborations - Clinical and Translational Science Institute

The Clinical and Translational Science Institute (CTSI) of Southeast Wisconsin is a consortium of eight Milwaukee institutions working in partnership to cultivate biomedical research as a signature strength of the region while advancing patient care and education.
        
Member institutions are:

  • Medical College of Wisconsin (MCW)
  • Marquette University
  • Milwaukee School of Engineering (MSOE)
  • University of Wisconsin-Milwaukee (UWM)
  • BloodCenter of Wisconsin (BCW)
  • Children's Hospital of Wisconsin (CHW)
  • Froedtert Hospital
  • Zablocki VA Medical Center

In 2013, the CTSI provided support for 66 collaborative research studies.

These studies are conducted by investigators from 16 institutions: Acceleron Pharma, Inc., AIDS Resource Center of Wisconsin, Aurora Healthcare Sinai Hospital, BCW, CHW, Cleveland Clinic, Dryhootch of America, Emory University, Harvard Medical School, Marquette University, MCW, Medical University of S. Carolina, MSOE, UW-Madison, UW-Milwaukee, VA

TITLE OF STUDY

Collaborating Institution

# of Researchers on Study per Institution

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects with Acute Spinal Cord Injury MCW 3
CHW* 1
A Phase 3 Clinical Study to Determine the Safety and Efficacy of rVWF:rFVIII and r VWF in the Treatment and Prevention of Bleeding Episodes in Subjects Diagnosed with von Willebrand Disease CHW* 3
MCW 1
A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Elvitegravir/Cobicistat/ Emtricitabine/Tenofovir Alafenamide Vs Elvitegravir/ Cobicistat/ Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Positive, Antiretroviral Treatment- Naïve Adults MCW 5
ARCW AIDS resource
center of WI
1
A Single Ascending Dose Phase I Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Biologic Activity of Intravenous NKTT120 in Adults with Stable Sickle Cell Disease BCW* 1
MCW 1
A Worldwide, Multicenter, Double-Blind, Randomized, Placebo-Controlled, 12-Week Study to Assess the Efficacy and Tolerability of Anacetrapib When Added to Ongoing Lipid-Lowering Therapy in Adult Patients with Homozygous Familial Hypercholesterolemia (HoFH) with a 52-Week Open-Label Extension MCW 2
Assessment of the Benefits, Risks, and Costs of Neonatal Screening for Cystic Fibrosis CHW* 2
UW-Madison 1
Assessment of the Contribution of Platelet TFPI to the Severity of Bleeding in Patients with Hemophilia: Phase II BRI 1
CHW 2
Brain Activation and the Stress Response during Motor Performance in Older Adults MCW 2
Marquette Univ 2
Cell based Model to study dystrophic cardiomyopathy MCW 2
CHW 1
Deoxyguanosine monophosphate (dGMP) and Deoxyadenosine monophosphate (dAMP) Treatment for DGUOK Deficiency CHW* 1
Univ. S. Carolina 1
Development of a prototype, fuzzy logic-based mobile application and web interface for self management of T2DM MCW 3
UW-Milwaukee 1
MSOE 1
Differences in the characteristics of the visceral and subcutaneous adipose tissue MCW 8
CHW 1
Effect of Adenosine 2A Receptor Agonist Regadenoson on Microvascular Blood Flow in Sickle Cell Anemia MCW 4
CHW 1
Effect of early rest on recovery from pediatric concussion CHW* 2
MCW 1
Effects of Altered Perfusion on Neuromuscular Fatigue and Leg Function Post Stroke MCW 1
Marquette Univ 1
Fibrocytes in Sickle Cell Disease MCW 4
CHW 4
fMRI Analysis of Working Memory Deficits in Children with Posterior Fossa Tumors MCW 2
CHW 2
fMRI and Robot-Assisted Practice of Activities of Daily Living MCW 11
UW-Milwaukee 1
fMRI and Robot-Assisted Practice of Activities of Daily Living: Case Studies MCW 8
UW-Milwaukee 1
fMRI of the Person Identity Network: Aging and APOE MCW 3
Marquette Univ 1
UW-Milwaukee 1
Cleveland Clinic 1
Gender differences in the effects of insulin resistance in African Americans plus survey, Factors Affecting AA Participants in Clinical Research MCW 5
CHW 1
Gene Identification of Childhood Kidney Disease CHW* 5
CHW 1
Genetic Analysis Of Children With And Without Inflammatory Bowel Disease (IBD) CHW 3
Emory Univ 1
Genetic Basis of Hemangiomas CHW* 2
MCW 1
Genetic Modifiers in Cystic Fibrosis MCW 1
CHW 1
Genetic Studies of Human Development Disorders CHW* 1
MCW 1
GORE HELEX™ Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke or Imaging- Confirmed TIA in Patients with Patent Foramen Ovale (PFO MCW 4
CHW 1
Human Brain Imaging during Locomotion Marquette Univ 6
MCW 5
Inflammatory markers, physical fitness, and pain in obese children and adolescents Marquette Univ 4
CHW 2
Intestinal Microbiota and the Pathogenesis of Cardiovascular Disease MCW 5
CHW 1
Intrauterine and Perinatal Bisphenol-A and Neonatal Body Composition CHW* 4
UW-Milwaukee 1
Mapping the Effects of the KIAA0319 Dyslexia Susceptibility Gene on the Neural Substrates of Reading MCW 3
CHW 1
Measuring Body Composition with Spina Bifida: A Pilot Study CHW 3
Marquette Univ 1
UW-Milwaukee 1
Mechanism and Repository Study (MARS) for the Red Cell Storage Duration Study MCW 3
BCW 1
Molecular Variants Causing von Willebrand Disease CHW* 4
MCW 1
Mpex 207: A Phase 3, Multi-Center, Multinational, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MP 376 (Levofloxacin Inhalation Solution; Aeroquin) in Stable Cystic Fibrosis Patients CHW* 4
MCW 1
Mpex 209: A Phase 3, Open-Label, Randomized Trial to Evaluate the Safety and Efficacy of MP-376 Inhalation Solution (Aeroquin) Versus Tobramycin Inhalation Solution (TIS) in Stable Cystic Fibrosis Patients CHW* 4
MCW 3
Pathophysiological Mechanisms in Type I vWD CHW* 4
MCW 1
PREMIUM-Prospective Randomized investigation to Evaluate incidence of headache reduction in subjects with Migraine and PFO Using the AMPLATZER PFO Occluder compared to medical Management. IDE#: G050054 MCW 5
CHW 1
Safety of Adenosine 2AA Agonist Lexiscan in Children and Adults with Sickle Cell Disease MCW 3
CHW 1
Self-management Guided Discharge Teaching for Parents of Hospitalized Children: A Pilot Study (Short title = The Discharge Study) CHW 2
Marquette Univ 1
UW-Milwaukee 2
Stroke with transfusions changing to hydroxyurea (SWiTCH): a phase III randomized clinical trial to compare standard therapy (erythrocyte transfusions with iron chelation) with alternative therapy (hydroxyurea with phlebotomy) for the prevention of secondary stroke and the management of iron overload in pediatric subjects with sickle cell anemia and previous stroke CHW* 2
MCW 1
The Aging Brain: Imaging Genetics of Brain Structure and Function MCW 1
UW-Milwaukee 1
The effect of combining prebiotic treatment with a diet/physical activity educational program on body composition and intestinal microbiota among predominately overweight and obese children Marquette Univ 1
CHW 2
The Effect of Tailored Step-Count Feedback on Vascular Homeostasis and Cardiovascular Performance in the Patients with and without underlying coronary artery disease MCW 3
UW-Milwaukee 1
"Title: Clinical Study to Identify the Source and Pathogenesis of BK Virus in Renal Transplant Recipients." CHW* 4
MCW 3
Use of FMRI to Study Brain Activation following Rectal Stimulation in Children with IBD CHW* 3
MCW 1
Whole Genome Sequencing CHW* 2
MCW 2
Wisconsin Alzheimer’s Disease Research Center MCW 7
UW-Madison 1
Wisconsin Pediatric Cardiac Registry:  Consent for Involvement and Participation in Environment and Genetic Studies CHW* 1
MCW 1
Assessment of Coupling Between Mass Neural Activity and the Hemodynamic Response in Humans MCW 1
Marquette Univ 1
Characterizing the Neural Basis of Extinction of Conditioned Fear as the Critical Component Exposure Therapy for PTSD MCW 1
UW-Milwaukee 4
Design of Immunomudulatory Peptides from the HTLV-2 Tax Protein MCW 4
VA** 1
Development of Novel Therapeutics for Triple-Negative Breast Cancer MCW 5
Effects of Altered Perfusion on Neuromuscular Fatigue and Leg Function Post Stroke MCW 1
Marquette Univ 2
Highly Sensitive Non-Invasive Method to Monitor Cardiac Transplant Rejection MCW 8
Marquette Univ 1
Inflammatory Markers, Physical Fitness and Pain in Children CHW 1
MCW 3
Marquette Univ 5
Inhibition of Activin Type IIB Receptor Signaling as a Treatment for Nemaline Myopathy Acceleron Pharma, Inc. 1
Harvard 1
MCW 5
Marquette Univ 1
mPeer: Mobile Detection of High Risk Behavior in Veterans- A Sociotechnical Systems Approach MCW 3
Dryhootch of America 3
Marquette Univ 1
VA** 1
Multi-scale pharmacokinetic modeling of imaging biomarkers for assessing acute lung injury MCW 2
Marquette Univ 2
New Hypoxia Radiosensitizers as Targeted Anticancer Agents MCW 4
UW-Milwaukee 2
Novel Small Molecules to Treat Radiation Injury MCW 2
Parent/Nurse Controlled Analgesia for Post-Operative Pain Management in Neonates: A Preliminary Randomized Controlled Trial CHW 1
MCW 11
Pilot Intestinal Microbiota and the Pathogenesis of Cardiovascular Disease MCW 7
Tetrahydrobiopterin in Neonatal Hyperoxic Lung Injury Aurora Healthcare
Sinai Hospital
1
MCW 2
Marquette Univ 1
Translating iPSCs to study genotype-phenotype correlations of dystrophic cardiomyopathy CHW 1
MCW 3

* Primary CHW investigator has faculty appointment at MCW
** Primary investigator has joint appointment MCW & VA

Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 955-8296
Directions & Maps
© 2016

Page Updated 04/07/2015
Top