Radiation Oncology

Research Presented in 2006

American Society of Clinical Oncology (ASCO)
Gastrointestinal Cancer Symposium
January 26-28, 2006
San Francisco, CA

• Intensity modulated radiation therapy for the treatment of anal cancer: Effect on acute toxicity. C Hwang, W Small, A Shivnani, S Hoover, K Kiel.
• A randomized phase II trial of weekly gemcitabine (G) paclitaxel (P) and external irradiation followed by the farnesyl transferase inhibitor R115777 (NSC#702818) for locally advanced pancreatic cancer (RTOG 0020). T Rich, J Harris, H Safran, J Hoffman, B Erickson, C Willett, PR Anne, R Myerson, MC Burkhardt.

American Society of Clinical Oncology (ASCO)
Prostate Symposium
February 24-26, 2006
San Francisco, CA

• Long term treatment sequelae following external beam irradiation + hormonal manipulation for adenocarcinoma of the prostate: Analysis of RTOG studies 85-31, 86-10, and 92-02. C Lawton K Bae M Pilepich G Hanks W Shipley.

American College of Sports Medicine (ACSM)
2006 Annual Meeting
May 31-June 3, 2006
Denver, CO

• Mechanisms of fatigue in cancer survivors. AV Ng C Alt C, E Gore, et al.

American Society of Clinical Oncology (ASCO)
42nd Annual Meeting
June 2-6, 2006
Atlanta, GA

• Intervertebral administration of 153Samarium with Kyphoplasty for vertebral metastases. HE Ashamalla, E Cardoso, L Weng S Rafla, MJ Macedon, N Panigrahi.

American Association of Physicists in Medicine (AAPM)
47th Annual Meeting
July 30-August 3, 2006
Orlando, FL

• Systematic study of inter-fractional variations for anatomic sites from head to feet. XA Li, X Qi, K Mueller, P Jursinic, B Erickson, D Wang, C Schultz, S Firat, JF Wilson.
• Developing in-line kV fluoroscopic verification for 4D adaptive radiotherapy. XA Li, A Khameni, A Tai, K Khater, JC Celi, D Hristov, B Ofstad.
• Monte Carlo simulation of TomoTherapy: derivation of a dual source model for treatment planning. Y Hsiao, R Steward, GH Olivera, KJ Ruchala, XA Li.
• Real time tracking of respiratory tumor motion based on external breathing output. J Zhang, Y Wu, W Liu, C Stepaniak, A Tai, E Gore, XA Li.
• Dependence of planar IMRT QA on MLC positional inaccuracies. E Ahunbay, P Jursinic, XA Li.
• Estimate of radiobiological parameters from clinical data for treatment planning of liver irradiation. A Tai, B Erickson, K Khater, XA Li.
• Development of an integrated software platform for treatment documentation and outcome analysis for IGRT. G Chen, C Schultz, XA Li.
• Implementation of good laboratory practice standards for improving dosimetry in radiobiology lab. N Morrow, G Chen, A Tai, XA Li.
• Development of an inverse optimization package for non-uniform dose distribution based on spatially inhomogeneous radiosensitivity. G Chen, E Ahunbay, XA Li.
• Direct aperture optimization based step-and-shoot IMRT with respiratory gating. E Ahunbay, P Jursinic, XA Li.
• EUD-assessed impacts of respiratory motion on breast irradiation. XS Qi, F Lopez, C Driscoll, J White, JF Wilson, XA Li.
• Radiobiological concerns on prolonged IMRT delivery for head-and-neck carcinoma. XS Qi, Q Yang, Y Feng, D Wang, XA Li.
• Radiobiology consideration in optimization of radiation treatment outcome for head and neck carcinoma. XS Qi Q Yang XA Li, JF Wilson, D Wang.

American Head and Neck Society (AHNS)
2006 Annual Meeting
August 17-20, 2006
Chicago, IL

• P129 toxicity outcomes in intensity-modulated radiation therapy vs 3-dimensional conformal radiotherapy for head and neck squamous cell carcinoma with unknown primary. JA Call, D Wang, S Firat, RW Byhardt, S Wong B Campbell C Schultz.

American Society of Radiotherapy and Oncology (ASTRO)
Radiation Oncology Translational Research Symposium
September 2006
Boston, MA

• Synergistic effect of 15-Lipoxygenase 2 and radiation on carcinoma cells of head and neck. Q Yang, Y Feng, XS Qi, XA Li, CJ Schultz, D Wang.

European Society for Therapeutic Radiology and Oncology (ESTRO)
25th Annual Meeting
October 8-12, 2006
Liepzig, Germany

• Improvements in dose homogeneity in the treatment of breast cancer over time without intensity modulated radiation therapy. C Hwang K Kiel.

Connective Tissue Oncology Society (CTOS)
12th Annual Meeting
November 2-4, 2006
Venice, Italy

• Initial experience with tomotherapy of large sarcoma of extremity or trunk. D Wang, D King, D Hackbarth, XA Li, JF Wilson.

American Society of Radiotherapy and Oncology (ASTRO)
47th Annual Meeting
November 5-9, 2006
Philadelphia, PA

• Slow and reproducible respiration with novel Qigong breathing exercise. GY Jin, LL Jin, A Tai, EM Gore, XA Li.
• Inter-fractional variations in patient setup and anatomic change assessed by daily CT from helical tomotherapy. XA Li, XS Qi, K Mueller, P, Jursinic, BA Erickson, D Wang, CJ Schultz, SY Firat, JF Wilson.
• Radiobiological considerations in designing hypofractionated radiation treatments for liver irradiation. A Tai, B Erickson, K Khater, XA Li.
• Design of non-uniform dose distribution based on spatially inhomogeneous radiosensitivity extracted from biological images. GP Chen, E Ahunbay, C Schultz, XA Li.
• Reducing respiratory motion using a lordosis board and hand grips to encourage accessory muscle breathing. K Khater, B Erickson, A Tai, XA Li.
• Variation of lung DVH during respiration. K Kainz C Stepaniak, E, Gore, XA Li.
• Ranking complex IMRT plans using an EUD-based figure-of-merit index. XS Qi, XA Li, K Kainz, B Brammer, GH Olivera, KJ Ruchala, C Schultz, JF, Wilson.
• Initial experience with simultaneous integrated boost for the treatment of glioblastoma multiforme: Clinical, dosimetric and radiobiologic analysis. C Hwang, A Lujan, M Gopalakrishnan, D, Boga, M Marymont.
• Temporal changes in measurement parameters of tumor and normal uterus during radiation therapy in cervical cancer: Significance for image-based brachytherapy. J Grecula N Mayr R Koch J Wang, H Zhang J Montebello R Poetter B Erickson, C Haie-Meder, W Yuh.
• Ten year follow up of RTOG 92-02: A phase III trial of the duration of elective androgen deprivation in locally advanced prostate cancer. GE Hanks, K Bae, A Porter, D Grignon, H Brereton, V Venkatesan, E Horwitz, C Lawton, H Sandler, W Shipley.
• Biochemical recurrence and late toxicity following external beam radiotherapy combined with permanent source prostate brachytherapy: Analysis of RTOG 0019. W Lee, K Bae, C Lawton, M Gillin, G Morton, S Firat, M Baikadi, K Greven, M Kuettel, H Sandler.
• A phase II trial of brachytherapy alone following lumpectomy for select breast cancer: Tumor control and survival outcomes of RTOG 95-17. DW Arthur K Winter, RR Kuske J Bolton, R Rabinovitch, J White, WF Hanson, RM Wilenzick B McCormick
• Breast irradiation in the prone position using 3D planning in women with large pendulous breast undergoing breast conservation for early stage disease. T Kelly H Lim J, Wagner N Morrow JF Wilson J White.
• Anal cancer treated with intensity modulated radiation therapy (IMRT) and concurrent chemotherapy: A dosimetric analysis of acute gastrointestinal toxicity. K Devisetty, LK Mell, JK Salama, AB Jani, AJ Mundt, JC Roeske, B Aydogan, SJ Chmura.
• Multicenter outcome of anal canal cancer patients treated with IMRT. JK Salama, LK Mell, K Devisetty, AB Jani, AJ Mundt, JC Roeske, SJ Chmura.
• Dosimetric predictors of acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity modulated radiation therapy (IMRT). LK Mell, JK Salama, JC Roeske, K Devisetty, AB Jani, AJ Mundt, SJ Chmura.
• A novel approach using vertebral intracavitary cement and samarium (VICS) for painful vertebral metastases. H Ashamalla, E Cardoso, S Rafla, L Weng, MJ Macedon, A Guirguis, B Mokh tar, C Ikoro, N Panigrahi.
• Phase II multi-institutional study of IMRT for oropharyngeal cancer (RTOG 00-22). A Eisbruch, J Harris, A Garden, C Chao, W Straube, C Schultz, G Sanguineti, C Jones, W Bosch, KK Ang.
• An update of phase II results of RTOG 02-11: A phase I/II Study gefitinib + radiation for newly diagnosed glioblastoma patients. A Chakravarti B Berkey, H Robins, A Guha, W Curran, D Brachman, C, Schultz, M Mehta.
• Dose-per-fraction escalation for localized prostate cancer - A multi-institutional phase I/II trial. MA Ritter, JD Forman, DG Petereit, PA Kupelian, D Wang, W Walker, JF Fowler, WA Tome.
• Is FDG-PET valuable in assessment of tumor response in head and neck carcinoma following definitive radiotherapy? D Wang, CJ Schultz, M Michel, S Rand, S Wong, B Campbell, JF Wilson JF.

Societe Internationale d'Urologie (SIU)
2006 World Congress
November 12-16, 2006
Cape Town, South Africa

• Is adjuvant androgen deprivation therapy a treatment of curative intent? N Fleshner N, T Keane C Lawton et al.

Society for Neuro-Oncology (SNO)
11th Annual Meeting
November 16-19, 2006
Orlando, FL

• RTOG 02-27: Phase I/II study of pre-irradiation chemotherapy with Methotrexate, Rituximab, and Temozolomide and post-irradiation temozolomide for primary central nervous system lymphoma. J Glass, B Berkey, C Schultz.

San Antonio Breast Cancer Symposium (SABCS)
29th Annual Meeting
December 14-17, 2006
San Antonio, TX

• Exploring helical TomoTherapy for simultaneously irradiating breast and regional nodes in prone position. K Kainz, J, White, J, Herman, M England, XA Li.
• Toxicity and cosmetic outcome from multi-catheter accelerated partial breast irradiation in early stage breast cancer patients. J Bovi J Rownd H Lim, J White.