Radiation Oncology

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Research Presented in 2011

American Society of Clinical Oncology (ASCO)
2011 Gastrointestinal Cancers Symposium
January 20-22, 2011
San Francisco, CA

  • Patterns of radiotherapy practice in the management of gastric cancers: Preliminary findings from the quality research in radiation oncology (QRRO) GI committee process surveys.  KA Goodman, N Khalid, LA Kachnic, BD Minsky, C Crozier, JB Owen, JF Wilson, CR Thomas Jr.
  • Helical tomotherapy for anal cancer: Initial clinical outcomes and organ motion. M Siker, XS Qi, B Hu, SJ Wong, XA Li, B Erickson.

American Society for Therapeutic Radiology and Oncology (ASTRO)/Radiological Society of North America (RSNA)
Cancer Imaging and Radiation Therapy Symposium
April 29-30, 2011
Atlanta, GA

  • Interfractional target volume changes with the use of 3Tesla MRI for cervical intracavitary image-guided brachytherapy.  C Bergom, N Morrow, J Rownd, E Paulson, T Kelly, B Erickson.
  • Evaluation of breast tissue marker impact on advanced MR and CT image quality. ES Paulson, RW Prost, MB Gonyo, XA Li, KM Schmainda, JA White. 

American Radium Society (ARS)
93rd Annual Meeting
April 30-May 4, 2011
Palm Beach, FL

  • Role of Consolidative thoracic radiation therapy in patients with extensive stage small cell lung cancer. ML Siker, T Suboc, Devisetty K, Firat SY, Choong N, Gore E. 

The Pancreas Club, Inc.
45th Annual Meeting
May 6-7, 2011
Chicago, IL

  • Pathologic response rates in patients receiving neoadjuvant chemoradiation for resectable/borderline resectable pancreatic cancer.
     Kelly T, Evans D, Erickson B. 

American Society of Clinical Oncology (ASCO)
2011 Annual Meeting
June 3-7, 2011
Chicago, IL

  • Phase II trial of neoadjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): Long-term follow-up of RTOG 0132. D Wang, Q Zhang, CD Blanke, GD Demetri, MC Heinrich, JC Watson, JP Hoffman SH Okuno, JM Kane,  M von Mehen, BL Eisenberg.
  • RTOG 0525: A randomized phase III trial comparing standard adjuvant temozolomide (TMZ) with a dose-dense (dd) schedule in newly diagnosed glioblastoma (GBM). MR Gilbert, M Wang, D Aldape, R Stupp, M Hegi, A Jaeckle, TS Armstrong, JS Wefel, M Won, DT Blumenthal A Mahajan, CJ Schultz, SC Erridge, PD Brown, A Chakravarti, WJ Curran, MP Metha. 
  • Molecular correlates from a randomized phase III trial of newly diagnosed glioblastoma. KD Aldape, M Wang, EP Sulman, M Hegi, H Colman, G Jones, A Chakravarti, MP Metha, DW Andrews, L Long, K Diefes L Heathcock, R Jenkins, CJ Schultz, MR Gilbert, Radiation Therapy Oncology Group RTOG 0525.
  • Prognostic significance of QOL Deterioration during early lung cancer survivorship: Secondary analysis of RTOG 0212 and 0214.  V Gondi, R Paulus, DW Bruner, CA Meyers, EM Gore, A Wolfson, M Werner-Wasik, H Choy B Movsas.
  • Phase III trail comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma. K Aldape, M Wang, E Sulman, M Hegi, H Colman, G Jones, A Chakravarti, M Mehta, D Andrews, L Long, K Diefes, L Heathcock, R Jenkins, CJ Schultz, MR Gilbert.
  • Early toxicity results with 3D conformal external beam therapy (CEBT) from the NSABP B-39/RTOG 0413 accelerated partial breast irradiation (ABPI) trial. TB Julian, JP Costantino, FA Vicini, JR White, KA Winter, DW Arthur, RR Kuske, R Rabinovitch, DS Partda, EP Mamounas, WJ Curran, N Wolmark.
  • Efficacy endpoints of RTOG 0247: A randomized phase II study of neoadjuvant capecitabine (C) and Irinotecan (I) and Oxaliplatin (O) with concurrent radiation therapy (RT) for locally advanced rectal cancer. SJ Wong, J Moughan, NJ Meropol, PR Anne, L Kachnic, A Rashid, JC Watson, EP Mitchell, J Pollock, RJ Lee, M Haddock, BA Erickson, CG Willett.

International Association for the Study of Lung Cancer (IASLC)
14th World Conference on Lung Cancer
July 3-7, 2011
Amsterdam RAI, the Netherlands

  • Extensive stage small cell lung cancer: Metastatic presentation, progression, and implications for oligometastatic treatment. K Devisetty, ML Siker, T Suboc, N Choong, E Gore.
  • Using during-RT PET to individualize adaptive RT for patients with Stage III NSCLC: A multicenter planning study. FM Kong, Y Xiao, M Machtay, M Werner-Wasik, GM Videtic, BW Loo, H Wagner, EM Gore, J Varlotto S Faria, TJ Dilling, A Sun, T Swanson, L Wang J Galvin, RK Ten Haken, J Bradley.
  • Incidence and impact syndrome of inappropriate anti-diuretic hormone hypersecretion (SIADH) in small cell lung cancer (SCLC). N Choong, M Siker, T Suboc, K Devisetty, P Foy, EM Gore.
  • Pulmonary resection after high dose radiation therapy (>59 Gy) and concurrent chemotherapy for non-small cell lung cancer. EM Gore, M Gasparri, K Devisetty, N Choong, W Tisol, G Haasler.
  • RTOG 0229: A phase II trial of concurrent chemotherapy and full dose radiotherapy followed by surgical resection and consolidative therapy for locally advanced non-small cell carcinoma of the lung. MJ Edelman R Paulus M Suntharalingam, M Krasna, W Burrows, EM Gore, SS Yom, H Choy.

American Association of Physicists in Medicine (AAPM)
2011 Joint AAPM/COMP Meeting
July 31-August 4, 2011
Vancouver, British Columbia, Canada

  • Model prediction of radiation induced duodenal toxicity for a dose escalation in radiation therapy of pancreatic cancer using published reports.  P Prior, B Erickson, XA Li. 
  • Dosimetric feasibility of dose escalation with gated IG-IMRT for pancreatic cancer.  F Liu, XA Li.
  • Static-gantry and rotational IMRT with flattening filter free versus flattening filtered beams. G Chen X Hu, K Kainz, Y Chang, XA Li.
  • A comparison of TomoTherapy and respiratory‐gated IG‐IMRT for the treatment of pancreatic cancer. D Prah, B Erickson, XA Li.
  • Improving effectiveness of an online adaptive replanning method for pancreas irradiation. E Ahunbay, F Liu, XA Li.
  • A planning and delivery study of a rotational IMRT technique with burst delivery. K Kainz, G Chen, Y Chang, D Prah, XS Qi, H Shukla, J Stahl, XA Li.
  • Quality of Prostate IMRT plans generated using biological vs. dose volume constraints. V Semenenko G Chen, C Lawton, XA Li.
  • Interfractional variations in partial breast irradiation: Prone vs. supine.  N Morrow, M Carver, J White, XA Li.
  • Predicting individual lung tumor volume change during image‐guided radiation therapy for adaptive radiation therapy. A Tai, E Gore, XA Li.
  • Online adaptive radiotherapy for prostate cancer: Clinical implementation and initial experience. XA Li, E Ahunbay, C Peng, G Chen, F Liu, C Lawton.
  • “Step and Shoot MRI:” A simple acquisition method to reduce gradient nonlinearity‐induced geometric distortions for radiation treatment planning. ES Paulson, RW Prost, XA Li

14th International Congress of Radiation Research (ICRR)
August 28-September 1, 2011
Warsaw, Poland

  • Effects of age and gender on radiation pneumonitis and nephropathy. M Medhora, F Gao, J Narayanan, I Ionova, S Gruenloh, J Moulder, E Jacobs, B Fish.
  • Mitigation of combined injury to the lung and skin by captopril. E Jacobs, F Gao, A Schock, B Fish, J Narayanan, J Moulder, Z Lazarova, M  Medhora.
  • Mitigation of lung fibrosis in rats by enalapril started 35 days after irradiation. F Gao, J Narayanan, B Fish, J Moulder, E Jacobs, M Medhora. 
  • Understanding the mechanism of mitigation of radiation nephropathy by ACE inhibitors. B Fish, J Moulder, E Cohen, K Potempa, M Medhora.

American Society for Therapeutic Radiology and Oncology (ASTRO)
53rd Annual Meeting
October 2-6, 2011
Miami Beach, FL

  • Pattern and extent of failure in limited stage small cell lung cancer: Implications for oligometastatic treatment. K Devisetty, ML Siker, T Suboc, N Choong, E Gore.
  • Extensive stage small cell lung cancer: Patterns of failure after chest & cranial radiotherapy. ML Siker, K Devisetty T Suboc, N Choong, E Gore. 
  • RTOG Phase II trial of preoperative image-guided radiotherapy (IGRT) for primary soft tissue sarcoma of the extremity: acute toxicity report. D Wang, Q Zhang, DG Kirsch SH Okuno, JM Kane, XA Li, D Roberge S Finkelstein, T Delaney, BL Eisenberg.
  • Results of Patterns of Care Study of Patients treated with external beam radiotherapy for prostate cancer in 2004. D Wang, A Ho, X Wu, A Hamilton, M Goodman, S Fleming C Rao, C German, J Owen.
  • Estimation of prognostic variables for survival in patients with primary localized soft tissue sarcoma of extremity and trunk treated with neoadjuvant radiotherapy or chemotherapy. M Bedi, M Shivakoti, E Zambrano E Baynes, A Mautz, M DuBois, D King, J Charlson, D Hackbarth, D Wang.
  • Difference in rates of necrosis in patients with primary soft tissue sarcoma of extremity and trunk treated with neoadjuvant radiotherapy or neoadjuvant chemoradiotherapy. M Bedi, Zambrano E, D King, D Hackbarth J Charlson R Whitfield, D Wang.
  • Deformable imaging capability for the Radiation Therapy Oncology Group (RTOG) consensus atlas of musculoskeletal anatomy (CAMAS) for soft tissue sarcoma of the lower extremities. Finkelstein S, A Trotti, G Letson, M Russell, T DeLaney, K Alektiar, J Michalski, D Wang, T Kadir, C Stevens. 
  • Use of 3DCRT for node positive breast cancer does not result in excess lung and heart irradiation.  P Prior, I Sparks, JF Wilson, XA Li, J White.
  • Three-dimensional conformal radiation therapy (3D-CRT) for node positive breast cancer yields low morbidity and excellent local control. IV Sparks, P Prior, Q Xiang, JF. Wilson, A Walker, XA Li, J White.
  • Interfractional variations in overlap between organs at risk and target volume in pancreas irradiation. EE Ahunbay, XA Li.  
  • Dosimetry benefits from the advanced radiation therapy delivery technologies. F Liu, A Tai, E Ahunbay, G Chen, X. Li.
  • Impact of daily image quality on image-guided radiotherapy for prostate cancer.  NV Morrow, C Lawton, S Qi, X. Li.
  • Five-year efficacy and toxicity outcomes from a Phase I/II Trial of increasingly hypofractionated radiation therapy for prostate cancer. MA Ritter, JD Forman, PA Kupelian, DG Petereit, CA Lawton, RJ Chappell.
  • Using an online adaptive replanning tool for offline adaptive radiotherapy. C Yang, F Lin, E Chang, C Lawton, C Schultz, S Firat, B Erickson, XA Li.
  • Developing a National Radiation Oncology Registry (NROR): A Radiation Oncology Institute (ROI) initiative. CM Rose, CA Lawton, JA Efstathiou, JE Bekelman, S Mutic, CR Bogardus, TR McNutt, AL Zietman, JR Palta.
  • Surrogate end-points for prostate cancer specific survival: Superiority of the interval to biochemical failure:An analysis of RTOG 92-02 and 94-13. DA Hamstra, J Dignam, A Porter, G Hanks, C Lawton, M Roach, H Sandler. 
  • Patterns of Brachytherapy Practice with Carcinoma of the Cervix (2005-2007): A QRRO Study. BA Erickson, A Ho, J Rownd, N Khalid, J Owen, P Eifel.
  • Daily dose variations in normal organs during radiation therapy for pancreatic cancer. F Liu, B Erickson, C Peng, XA Li.
  • Predictive value of tumor recurrence using urinary vacular endothelial growth factor levels in patients receiving radiation therapy for glioblastoma RTOG 0611. K Camphausen, M Wang, C Graves, B Corn, T Muanza, S Howard, A Mahajevan, C Schultz, M Haas, M Mehta.
  • Angiotensin converting enzyme inhibitor mitigation of radiation pneumonitis. JR Kharofa, E Cohen, R Tomic, Q Xiang, EM Gore.
  • Using during RT PET to individualize adaptive RT for patients with Stage III NSCLC: A RTOG planning study. FP Kong, M Machtay, G Videtic, BW Loo, EM Gore, H Wagner, J Varlotto, S Faria, TJ Dilling.
  • Decline in tested and patient-reported cognitive functioning following prophylactic cranial irradiation for lung cancer: Secondary analysis of RTOG 0121 and 0214. V Gondi, R Paulus, DW Bruner, CA Meyers, EM Gore, A Wolfson, M Werner-Wasik, H Choy, B Movsas.
  • Examining the association of BMI with breast cancer recurrence and survival in early stage breast cancer cohort with high median BMI: Size matters. CR Bergom, A Szabo S, Mo, M Bedi, J Kharofa, JF Wilson, J White.

Connective Tissue Oncology Society (CTOS) and the Musculoskeletal Tumor Society (MSTS)
2011 Combined Annual Meeting
October 26-29, 2011
Chicago, IL

  • Prognostic variables for post-metastasis survival in patients with soft tissue sarcoma of the extremity and trunk. M Bedi, D King, D Hackbarth, J Charlson, R Whitfield, D Wang.
  • The use of perforator flaps in the reconstruction of soft tissue sarcoma defects: An initial experience. RM Whitfield, D King, S Pappas, M Bedi, D Wang, D Hackbarth.

American Public Health Association (APHA)
139th Annual Meeting and Exposition
October 29-November 2, 2011
Washington, DC

  • Geographic disparity in the use of radiation therapy (RT) for prostate cancer (PC) patients in Wisconsin (WI). A Ho, D Wang, J Owen, JF Wilson.

International Society of Geriatric Oncology (SIOG)
11th Annual Meeting
November 4-5, 2011
Paris, France

  • Multimodality therapy in advanced head and neck cancer utilization in the geriatric population. BL Massey, E Guerard, S Wong, D Wang, BH Campbell, C Schultz.

Center for Medical Countermeasures against Radiation
Annual Directors Meeting
National Institute of Allergy and Infectious Diseases (NIAID)
November 7-8, 2011

  • Mitigation of Combined Injury by Radiation to Lung and Skin by Captopril.  M Medhora, E Jacobs, F Gao, Ay Schock, B Fish, J Narayanan, J Moulder, Z Lazarova. 

San Antonio Breast Cancer Symposium
34th Annual Meeting
December 6-10, 2011
San Antonio, TX

  • Analysis of Heart Dose-Volume Parameters and Cardiac Events among Node Positive Breast Cancer (NPBC) Patients Treated with Three-Dimensional Conformal Radiation Therapy (3D-CRT). J Bradley, P Prior, I Sparks, Q Xiang R Santana-Davila, A Walker, JF Wilson, XA Li, J White.
  • Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) vs Partial Breast Irradiation (PBI) for Women with Stage 0, 1, or 2 Breast Cancer: NSABP B-39/RTOG 0413. TB Julian, JB Costantino, FA Vicini, JR White, RS Cecchini, KA Winter DW Arthur, R Kuske, R Rabinovitch, DS Parda, EP Mamounas, WJ Curran Jr.


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