Radiation Oncology

Research Presented in 2012

Multidisciplinary Head and Neck Cancer Symposium
January 26-28, 2012
Pheonix, AZ

• MRI analysis of changes in tumor characteristics in patients with head and neck squamous cell carcinoma treated with concomitant chemoradiation. J Bradley, E Paulson, D Wang, S Wong, C Schultz, B Campbell, B Massey XA Li.
• Elective lymph node irradiation with IMRT: Is conventional dose fractionation necessary?  M Bedi, S Firat, V, Semenenko, C Schultz, P Tripp, R Byhardt, D Wang.

United States and Canadian Academy of Pathology (USCAP)
2012 Annual Meeting
March 17-23, 2012
Vancouver, BC, Canada

• Pathologic response to neoadjuvant radiotherapy (NRT) as potential prognostic factors in soft tissue sarcomas. JC Chang, M Bedi, DI Stockman, D Wang, E Zambrano.

American Radium Society (ARS)
94th Annual Meeting
April 28-May 2, 2012
Las Vegas, NV

• Characterization of interfractional anatomic changes in breast irradiation: An indication for adaptive radiotherapy. X Chen, J White, W Li, JF Wilson, XA Li.
• Modified prone whole breast irradiation allows coverage of low axillary lymph nodes: Personalized radiotherapy in the post Z-11 era. C Bergom, P Prior, JF Wilson, A Currey, J White.

American Society of Clinical Oncology (ASCO)
2012 Annual Meeting
June 1-5, 2012
Chicago, IL

• A revised RTOG recursive partitioning analysis (RPA) model for glioblastoma based upon multi-platform biomarker profiles. A Chakravarti, M Wang, K Aldape, E Sulman, M Bredel, A Magliocco, A Klimowicz, M Hegi, R Stupp, M Gilbert, W Curran, M Werner-Wasik, A Mahajan, C Schultz, M Mehta.
• Phase 2b study evaluating efficacy and safety of gamma-D-glutamyl-L-tryptophan in attenuation of oral mucositis during chemoradiation in head and neck cancer patients. I Rios, WJ Alexander, DA Karlin, ST Sonis, CW Tuthill, MR Kudrimoti, W Zhen, D Adkins, BJ Bienvenu, CJ Schultz, JY Suen, H Kim, Y Chen, SR Katz, ML Venigalla, K Hu, PM Pathare, SM Witherby, CT Miyamoto, DL Schwartz.

Society for Epidemiologic Research (SER)
45th Annual Meeting
June 27-30, 2012
Minneapolis, MN

• Use of radiotherapy (RT) for prostate cancer (PC) patients in Wisconsin (WI).  Does geographic disparity exist?  A Ho, D Wang, J Owen, JF Wilson.
• Data quality (DQ) of Wisconsin Cancer Reporting System (WCRS) on prostate cancer (PC). A Ho, D Wang, J Owen, JF Wilson.

American Association of Medical Physicists (AAPM)
54th Annual Meeting
July 29-August 2, 2012
Charlotte, NC

• A comparison of various online strategies to account for interfractional variations for pancreatic cancer. E Ahunbay, F Liu, C Yang, XA Li.
• Accurate contour transfer between different image modalities using a hybrid deformable image registration and fuzzy connected image segmentation method. C Yang, ES Paulson, XA Li.
• Characterization of interfractional anatomical variations in post-operative irradiation therapy for prostate bed.  F Liu, E Ahunbay, R Christian, C Lawton, D Wang, XA Li.
• Consolidating duodenal/small bowel toxicity data via iso-effective dose calculations based On compiled clinical data. P Prior, A Tai, B Erickson, XA Li.
• Development of a QA software tool for automatic verification of plan data transfer and delivery. GP Chen, XA Li.
• Dosimetric benefits of online adaptive replanning for post-operative radiation therapy of prostate bed.  F Liu, E Ahunbay, C Lawton, XA Li.
• Extracting patient-specific radiobiological parameters for radiobiologically adaptive radiotherapy based on radiation response for lung cancer. A Tai, E Gore, XA Li.
• Feasibility of Mapping Transient Tumor Hypoxia using in situ Activation PET Imaging: A Simulation Study.  E Dalah, C Yang, I Moraru, ES Paulson, Q Zhang,  Y Hu, XA Li.
• High fidelity, low distortion tetrahedral diffusion-weighted MRI for radiation treatment planning. ES Paulson.
• Modeling of radiation-induced sensorineural hearing loss from IMRT and chemotherapy for nasopharyngeal carcinoma.  A Tai, J Wang, Y Bao, M Chen, XA Li.
• Optimal proton beam energy to treat adult CNS, adult head and neck, and pediatric cancers. K Kainz, S Firat, JF Wilson, XA Li.
• Practical issues for biologically based treatment planning.  XA Li.
• Radiation dose responses for chemoradiation therapy of pancreatic cancer: An analysis of compiled clinical data using biophysical models.  I Moraru, A Tai, B Erickson, XA Li.
• Significant inter-fractional variations of lumpectomy cavity in partial breast irradiation.  X Chen, J White, N Morrow, JF Wilson, XA Li.

American Society of Therapeutic Radiology and Oncology (ASTRO)
54th Annual Meeting
October 28-31, 2012
Boston, MA

• Adaptive replanning considering previously delivered dose for head and neck cancers.  E Ahunbay, B Kimura, C Schultz, X A Li.
• Cardiac sparing by respiratory-gating during whole abdominal irradiation Using 3DCRT for Wilms’ Tumor patients.  DE Prah, J Kharofa, S Firat.
• Combined online and offline adaptive radiation therapy. XA Li, C Yang, F Liu, E Ahunbay, Y Chang, C Schultz, D Wang, S Firat, B Erickson, C Lawton.
• CT-based 3DCRT planning for node positive breast cancer does not result in excess lung and heart doses P Prior, I Sparks, JF Wilson,  XA Li, J White.
• Cumulative dose with organ deformation for cervical cancer treated with multi-fraction high dose rate brachytherapy. NV Morrow, EE Ahunbay, JJ Rownd, XA. Li, B Erickson.
• Deformable breast MRI and CT registration for radiation treatment planning using B-spline with rigidity and feature point distance regularization. C Yang, J White, XA Li.
• Dosimetric benefits of online adaptive replanning for radiotherapy of prostate plus seminal vesicle: Evaluation based on cumulative dose. F Liu, E Ahunbay, Y Chang, C Lawton, XA Li.
• Feasibility of cardiac sparing splenic irradiation using IMRT for pediatric patients enrolled on the COG High-Risk Hodgkin’s Lymphoma Protocol.   JR Kharofa, D Prah, S Firat.
• Feasibility of generating synthetic ED and CT Images from conventional MR Images for brain radiotherapy.  ES Paulson.
• High negative predictive value of FDG-PET/CT in assessment of tumor response following radiation therapy for head and neck carcinomas: Long-term update. D Wang, M Michel, D Baruah, M Bedi, B Campbell, B Massey, S Wong,  C Schultz.
• Increase in tumor size on MRI is associated with greater pathologic necrosis and poor survival in patients with soft tissue sarcoma of extremity and body wall treated with neoadjuvant radiotherapy. M Bedi,  J Kharofa, J Chang, E Zambrano, K Baynes, A Mautz, M DuBois, D King, J Charlson, D Wang.
• Interobserver variation in suspicious edema definition for pre-operative radiotherapy in soft tissue sarcoma of the extremity. D Roberge, W Bosch, H Bahig, W Levin, I Petersen, M Haddock, C Freeman, T DeLaney, R Abrams, D Wang.
• Long term follow up of the RTOG 9501/Intergroup phase III trial: Postoperative concurrent radiation therapy and chemotherapy in high risk squamous cell carcinoma of the head and neck. JS Cooper, Q Zhang, AA Forastiere, J Jacobs, B Saxman, A Kish, AJ Cmelkak JF Ensley, CJ Schultz, SS Yom.
• Multimodality image-based target and normal structure delineation for dose painting of pancreatic cancer.  IC Moraru, E Dalah, J Wang, ES Paulson, BA Erickson, XA Li.
• Online adaptive replanning for partial breast irradiation. X Chen, J White, A Currey, JF Wilson, XA Li.
• Patient and tumor characteristics and pre-treatment swallowing frequency and duration in head and neck cancer patients. J Bradley, E Paulson, J Kharofa, XA Li, C Schultz, D Wang.
• PET-guided dose escalation for pancreatic cancer: a treatment planning study. E Dalah, F Liu, E Paulson, K Kainz, R Hellman, B Erickson, XA Li.
• Plan quality of proton vs. photon IG-IMRT. K Kainz, S Firat, C Schultz, JF Wilson, XA Li.
• Relationship of PTV margin with frequency of image-guide positioning.  A Tai, D Christien, R Lee, S Wu, XA Li.
• Sensorineural hearing loss in nasopharyngeal carcinoma patients treated with combined intensity modulated radiation therapy and cisplatin-based chemotherapy. J Wang, YY Chen, A Tai, S Huang, XW Deng, C Zhao, MiChen, XA Li.

Connective Tissue Oncology Society (CTOS)
17th Annual Meeting
November 14-17, 2012
Prague, Czech Republic

• Agreement in contouring suspicious edema by RTOG sarcoma radiation oncologists for pre-operative radiotherapy in soft tissue sarcoma of the extremity. D Roberge, W Bosch, H Bahig, W Levin, I Petersen, M Haddock, C Freeman, TF DeLaney, R Abrams, D Indelicato, E Baldini, Y Hitchcock, D Kirsch, K Kozak, D Wang.