Candice S. Klug, PhD

Candice S. Klug, PhD

Professor, Biophysics
Director, National Biomedical EPR Center
Program Director, Biophysics Graduate Program

(414) 955-4015


  • Massachusetts Institute of Technology (Cambridge, MA), BS, Chemistry (1994)
  • Medical College of Wisconsin (Milwaukee, WI), PhD, Biophysics (1999)
  • UCLA School of Medicine, Jules Stein Eye Institute (Los Angeles, CA), Postdoctoral Fellow in Ophthalmic Biophysical Chemistry (1999-2001)

Research Interests

My research interests currently focus on protein structure and dynamics. I use the site-directed spin labeling (SDSL) EPR spectroscopy technique to study the functional dynamics of soluble and membrane proteins essential to bacterial viability.

Research Projects

  • LptA-Mediated Transport of LPS is an R01 award from the National Institute of General Medical Sciences to study how LptA transports LPS. Genetic screenings, laser light scattering analyses, EPR spectroscopy studies, and isothermal titration calorimetry measurements are used to provide detailed insights into the mechanisms of LPS transport across the periplasm of Gram-negative bacteria.
  • National Biomedical EPR Center is a P41 award from the National Institute of Biomedical Imaging and Bioengineering. The mission of the EPR Center is to serve the community of EPR spectroscopists by development of advanced EPR instrumentation and new EPR methodology.

Lab Members

  • Kathryn Westfahl Schultz, Research Scientist
  • Matthew Fischer, Research Technologist

Recent Publications


Related Links

PubMed Publications