Healing Begins with Discovery

Pushing the frontiers of research to help those who suffer

Medical advances discovered by Medical College of Wisconsin cardiovascular researchers:


  • Substances produced by brain cells to trigger the growth of new blood vessels, an important clue as to how the brain works to combat the effects of a stroke.
  • How the body's reflexes control the heart and lung systems making general anesthesia safer.
  • The critical link between kidney blood flow regulation and the development of high blood pressure.
  • Female athletes experiencing amenorrhea (cessation of menstrual cycle) are at high risk for both cardiovascular disease and osteoporosis.
  • Automated external defibrillators, used in conjunction with cardiopulmonary resuscitation, double the chances of survival for cardiac arrest victims.
  • A gene that helps regulate triglyceride levels in the body. Elevated triglycerides, a fat component in the blood, are a significant risk factor in heart disease.
  • Techniques used during surgery and after surgery that resulted in the nation's best outcomes for a form of pediatric heart surgery (hypoplastic left heart syndrome surgery).
  • Higher levels of the hormone aldosterone in African Americans with high blood pressure. Aldosterone is secreted by the adrenal glands and causes salt retention by the kidneys.
  • The transfer of the renin gene from a strain of rat resistant to hypertension into the genetic background of a hypertensive strain restores the relaxation of cerebral arteries.
  • Novel genetic variants contributing to left ventricular hypertrophy in hypertensive individuals.
  • A way to create the first genetically modified rat using technology known as zinc finger nuclease, paving the way for the development of novel genetically modified animal models of human diseases.
  • Genes partially govern where the fatty deposits develop within the heart's arteries in patients.

CVC Research Contact Information

Allison DeVan, PhD
Academic Program and Research Consultant
(414) 955-5617 | adevan@mcw.edu

Cardiovascular Center
Medical College of Wisconsin
8701 Watertown Plank Rd.
Milwaukee, WI 53226-0509