Center for Biomedical Mass Spectrometry Research

Center for Biomedical Mass Spectrometry ResearchThe mission of the Center for Biomedical Mass Spectrometry Research is to provide access to basic and advanced mass spectrometry technologies for biomedical research to investigators at the Medical College of Wisconsin and partner institutions.

We aim to catalyze state-of-the-art interdisciplinary research, foster technology development, and provide education regarding the applications of mass spectrometry in biomedical research.

In the lab at the Center for Biomedical Mass Spectrometry Research

Lab staff in the Center for Biomedical Mass Spectrometry Research

Overall, the Center supports integrated research programs requiring targeted and discovery-driven analyses of biological molecules. Our technologies support identification, characterization, and quantitation of peptides, proteins, glycans, lipids, metabolites, and small molecules.

Our goals:

  • Provide high quality routine and advanced mass spectrometry-based analytical services
     
  • Establish collaborative research projects with basic and clinical investigators at MCW and partner institutions
     
  • Develop and disseminate novel methodologies and protocols to enable new types of analyses for which established protocols are not yet available
     
  • Educate trainees, staff and faculty in the applications of mass spectrometry in biomedical research
     
  • Disseminate our research findings to the scientific community at large

Frequently Asked Questions

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  How do I submit a sample for analysis?

The first step is always a consultation with Center staff to define the project. Once you have a project number, samples prepared using approved protocols are submitted directly to the MS Center researcher assigned to handle the project.

  Do you accept samples from outside MCW?

Yes! We work with external users – including academic and non-academic organizations.

  What do I need to avoid during sample preparation?

There are a lot of things that will render a sample unfit for mass spectrometry. Fortunately, we also have a lot of creative ways to remove unwanted contaminants – and it depends on what is in your sample and how much. This is one of the reasons why every projects begins with a consultation with experts within the Center so we provide you with approved standard operating protocols for sample preparation.

  How much sample do I need for my analysis?

There is no single correct answer. The minimum amount needed depends on the chemical characteristics of the analyte, complexity of matrix, instrument, and application (e.g. identification, quantitation, characterization). This is one of the reasons why every projects begins with a consultation with experts within the Center so we can guide you on the specific quantities necessary for your project goals.

  There are so many bioinformatic platforms available, how does the Center select which ones to use?

When possible, we use professionally developed software that is robust and validated by thousands of laboratories worldwide. As bioinformatic tools are constantly evolving, we pay special attention to new trends in the field by attending conferences, specialized training courses, and participate in beta testing for software developers.

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Support the Center

The Center for Biomedical Mass Spectrometry Research seeks support of its mission to expand our available technologies, accelerate new discoveries at the intersection of mass spectrometry, basic science, and clinical research, and enhance our scope in educating the next generation of scientists.

Your philanthropy supports:

  • Acquisition of new instrumentation
  • Pilot projects to fund innovative science in new research areas
  • Symposia to expand the reach of our educational mission
  • Outreach activities for local youth

Giving Information

Margaret Sobczak
Development Office
Director of Corporate Relations

(414) 955-4739 | (414) 955-6166 (fax)

msobczak@mcw.edu

Support the Center for Biomedical Mass Spectrometry Research

Contact Us

Center for Biomedical Mass Spectrometry Research (CBMSR)
Medical College of Wisconsin
8701 Watertown Plank Rd.
Milwaukee, WI 53222
mscenter@mcw.edu

All projects begin with a consultation  >  Schedule an appointment

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