Free Radical Research Center

Free Radical Research Center, Medical College of Wisconsin

The MCW Free Radical Research Center (FRRC) is a spin-off from the National Biomedical EPR Center, which was founded by Professor Harold Swartz in 1975 and subsequently funded as a Biotechnology Research Resource by the National Institutes of Health. Dr. Candice Klug is the director of the research resource. In 1988, the EPR research resource became part of the Molecular Biophysics branch of the Department of Biophysics.

The EPR Center played a vital role in promoting research activities related to both nitric oxide and oxy radical research at MCW. Many collaborations were conceived in order to define and investigate the role of nitric oxide and oxy radicals in cardiovascular, neurodegenerative, and inflammatory diseases. The EPR Center/Free Radical collaboration became a vital research component in many NIH-funded grant applications at MCW and other US institutions.

In September 2000, the MCW Free Radical Research Center was created as part of the Department of Biophysics.

Free Radical Research Center staff and equipment


  • To promote and stimulate free radical research at MCW
  • To help acquire increased NIH and other extramural funding for MCW researchers engaged in free radical and nitric oxide-related research
  • To promote increased collaborations in free radical research between basic scientists and clinical researchers


The MCW Free Radical Research Center is unique because it is closely associated with the EPR research resource and CIR's MRI facility. EPR is the only physical technique that can unambiguously detect free radicals in biological systems. State-of-the-art EPR facilities, fluorescence, and HPLC techniques are available at the FRRC.

Contact Us

Jacek Zielonka, PhD
Research Director, Free Radical Research Center
(414) 955-4789