The Application Submission System & Interface for Submission Tracking (ASSIST) is the NIH's online system for the preparation, submission, and tracking of grant applications through Grants.gov to NIH. ASSIST is used for NIH applications that are NOT eBridge System to System applications. Review the Grant Submission Portal (PDF) to determine whether you need to use ASSIST.
The following resources are available to support ASSIST users:
This video (14:26) outlines ASSIST basics: