Antje Kroner-Milsch, MD, PhD

Assistant Professor

Locations

Clement J. Zablocki VA Medical Center
Neuroscience Research Labs – Research 151
5000 W. National Ave.
Milwaukee, WI 53295

Education

MD, Julius-Maximilians-University, Wuerzburg, Germany, 2002
PhD, Julius-Maximilians-University, Wuerzburg, Germany, 2008
Postdoctoral Fellow, Neurology, Developmental Neurobiology, Julius-Maximilians-University, Josef Schneider Strasse, Wuerzburg, Germany, 2008-2009
Postdoctoral Fellow, Neurology, Centre for Research in Neuroscience, McGill University Health Centre, Montreal, Quebec, 2009-2014
Research Associate, Neurology, Centre for Research in Neuroscience, McGill University Health Centre, Montreal, Quebec, 2014-2015

Biography

Dr. Kroner-Milsch received her MD degree at Julius-Maximilian University, Wuerzburg, Germany in 2002. In 2008, she completed her PhD in Neuroscience under supervision of Dr. Rudolf Martini at Julius-Maximilian University in Wuerzburg investigating the role of immune cells in hereditary myelinopathies.

Following graduation she conducted a postdoctoral fellowship at McGill University in Montreal, Canada in Dr. Sam David’s laboratory. During her postdoctoral fellowship, she started working in the field of spinal cord injury. In 2014, she was promoted to Research Associate. Her work in Dr. David’s laboratory focused on the inflammatory response after spinal cord injury, in particular on the role of macrophages.

Dr. Kroner-Milsch joined the Medical College of Wisconsin in September, 2015 and is an Assistant Professor in the Department of Neurosurgery. She continues to explore the role of inflammation after spinal cord injury and aims to modify the inflammatory response in order to achieve improved outcome after spinal cord injury.

Honors and Awards

09/01/2005 – Young Investigator Award Multiple Sclerosis, Wyeth

Research Experience

Neurosciences
Spinal Cord Injuries

Methodologies and Techniques

Flow Cytometry
Histology
Spinal Cord Injuries

Research Interests

Therapeutic potential of modifying the inflammatory response after spinal cord injury

Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders.

(David S, Jhelum P, Ryan F, Jeong SY, Kroner A.) Antioxid Redox Signal. 2022 Jan 04 PMID: 34569265 09/28/2021
Correction to: CCL3 contributes to secondary damage after spinal cord injury.

(Pelisch N, Almanza JR, Stehlik KE, Aperi BV, Kroner A.) J Neuroinflammation. 2021 Apr 03;18(1):87 PMID: 33812368 PMCID: PMC8019158 04/05/2021
Use of a Self-Delivering Anti-CCL3 FANA Oligonucleotide as an Innovative Approach to Target Inflammation after Spinal Cord Injury.

(Pelisch N, Rosas Almanza J, Stehlik KE, Aperi BV, Kroner A.) eNeuro. 2021 Mar-Apr;8(2) PMID: 33632814 PMCID: PMC7986543 02/27/2021
CCL3 contributes to secondary damage after spinal cord injury.

(Pelisch N, Rosas Almanza J, Stehlik KE, Aperi BV, Kroner A.) J Neuroinflammation. 2020 Nov 27;17(1):362 PMID: 33246483 PMCID: PMC7694914 11/29/2020
Bilateral cervical contusion spinal cord injury: A mouse model to evaluate sensorimotor function.

(Reinhardt DR, Stehlik KE, Satkunendrarajah K, Kroner A.) Exp Neurol. 2020 09;331:113381 PMID: 32561411 SCOPUS ID: 2-s2.0-85086575731 06/21/2020
Role of microglia in spinal cord injury.

(Kroner A, Rosas Almanza J.) Neurosci Lett. 2019 09 14;709:134370 PMID: 31283964 07/10/2019
Myeloid cell responses after spinal cord injury.

(David S, Kroner A, Greenhalgh AD, Zarruk JG, López-Vales R.) J Neuroimmunol. 2018 08 15;321:97-108 PMID: 29957394 06/30/2018
Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration.

(Kaplan A, Morquette B, Kroner A, Leong S, Madwar C, Sanz R, Banerjee SL, Antel J, Bisson N, David S, Fournier AE.) Neuron. 2017 Mar 08;93(5):1082-1093.e5 PMID: 28279353 03/11/2017
Arginase-1 is expressed exclusively by infiltrating myeloid cells in CNS injury and disease.

(Greenhalgh AD, Passos Dos Santos R, Zarruk JG, Salmon CK, Kroner A, David S.) Brain Behav Immun. 2016 Aug;56:61-7 PMID: 27126514 04/30/2016
Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.

(Sadovnick AD, Traboulsee AL, Bernales CQ, Ross JP, Forwell AL, Yee IM, Guillot-Noel L, Fontaine B, Cournu-Rebeix I, Alcina A, Fedetz M, Izquierdo G, Matesanz F, Hilven K, Dubois B, Goris A, Astobiza I, Alloza I, Antigüedad A, Vandenbroeck K, Akkad DA, Aktas O, Blaschke P, Buttmann M, Chan A, Epplen JT, Gerdes LA, Kroner A, Kubisch C, Kümpfel T, Lohse P, Rieckmann P, Zettl UK, Zipp F, Bertram L, Lill CM, Fernandez O, Urbaneja P, Leyva L, Alvarez-Cermeño JC, Arroyo R, Garagorri AM, García-Martínez A, Villar LM, Urcelay E, Malhotra S, Montalban X, Comabella M, Berger T, Fazekas F, Reindl M, Schmied MC, Zimprich A, Vilariño-Güell C.) G3 (Bethesda). 2016 07 07;6(7):2073-9 PMID: 27194806 PMCID: PMC4938660 05/20/2016
Role of IL-10 in Resolution of Inflammation and Functional Recovery after Peripheral Nerve Injury.

(Siqueira Mietto B, Kroner A, Girolami EI, Santos-Nogueira E, Zhang J, David S.) J Neurosci. 2015 Dec 16;35(50):16431-42 PMID: 26674868 PMCID: PMC6605511 12/18/2015
Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS.

(Schrewe L, Lill CM, Liu T, Salmen A, Gerdes LA, Guillot-Noel L, Akkad DA, Blaschke P, Graetz C, Hoffjan S, Kroner A, Demir S, Böhme A, Rieckmann P, ElAli A, Hagemann N, Hermann DM, Cournu-Rebeix I, Zipp F, Kümpfel T, Buttmann M, Zettl UK, Fontaine B, Bertram L, Gold R, Chan A.) J Neuroinflammation. 2015 Dec 16;12:234 PMID: 26669675 PMCID: PMC4681148 12/17/2015

Antje Kroner-Milsch, MD, PhD