Jing Wu, PhD

Publications

• Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores.

  (Klemens CA, Chulkov EG, Wu J, Hye Khan MA, Levchenko V, Flister MJ, Imig JD, Kriegel AJ, Palygin O, Staruschenko A.) Hypertension. 2021 Feb;77(2):582-593 PMID: 33390052 01/05/2021

• Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension.

  (Wu J, Agbor LN, Fang S, Mukohda M, Nair AR, Nakagawa P, Sharma A, Morgan DA, Grobe JL, Rahmouni K, Weiss RM, McCormick JA, Sigmund CD.) Cardiovasc Res. 2021 Jan 01;117(1):308-319 PMID: 32428209 PMCID: PMC7797211 05/20/2020

• Cullin-3: Renal and Vascular Mechanisms Regulating Blood Pressure.

  (Wu J, McCormick JA, Sigmund CD.) Curr Hypertens Rep. 2020 Aug 27;22(9):61 PMID: 32852625 PMCID: PMC7477742 SCOPUS ID: 2-s2.0-85089899669 08/28/2020

• Increased Susceptibility of Mice Lacking Renin-b to Angiotensin II-Induced Organ Damage.

  (Nakagawa P, Nair AR, Agbor LN, Gomez J, Wu J, Zhang SY, Lu KT, Morgan DA, Rahmouni K, Grobe JL, Sigmund CD.) Hypertension. 2020 Aug;76(2):468-477 PMID: 32507043 PMCID: PMC7347438 SCOPUS ID: 2-s2.0-85087872461 06/09/2020

• The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity.

  (Ceddia RP, Downey JD, Morrison RD, Kraemer MP, Davis SE, Wu J, Lindsley CW, Yin H, Daniels JS, Breyer RM.) Prostaglandins Other Lipid Mediat. 2019 10;144:106353 PMID: 31276827 PMCID: PMC6778036 07/06/2019

• Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Protects From Angiotensin II-Induced Endothelial Dysfunction in Adult Offspring Born From Pregnancies Complicated by Hypertension.

  (Nair AR, Silva SD Jr, Agbor LN, Wu J, Nakagawa P, Mukohda M, Lu KT, Sandgren JA, Pierce GL, Santillan MK, Grobe JL, Sigmund CD.) Hypertension. 2019 07;74(1):173-183 PMID: 31104564 PMCID: PMC6561821 SCOPUS ID: 2-s2.0-85068196613 05/21/2019

• Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension.

  (Agbor LN, Nair AR, Wu J, Lu KT, Davis DR, Keen HL, Quelle FW, McCormick JA, Singer JD, Sigmund CD.) JCI Insight. 2019 06 11;5 PMID: 31184598 PMCID: PMC6675584 SCOPUS ID: 2-s2.0-85070660042 06/12/2019

• Tumour necrosis factor α sets area postrema on fire in renovascular hypertension.

  (Liu J, Wu J.) Cardiovasc Res. 2019 05 01;115(6):995-997 PMID: 30657874 SCOPUS ID: 2-s2.0-85065934454 01/19/2019

• RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity.

  (Mukohda M, Fang S, Wu J, Agbor LN, Nair AR, Ibeawuchi SC, Hu C, Liu X, Lu KT, Guo DF, Davis DR, Keen HL, Quelle FW, Sigmund CD.) J Clin Invest. 2019 03 21;129(6):2318-2332 PMID: 30896450 PMCID: PMC6546477 SCOPUS ID: 2-s2.0-85063644288 03/22/2019

• Interference With Endothelial PPAR (Peroxisome Proliferator-Activated Receptor)-γ Causes Accelerated Cerebral Vascular Dysfunction in Response to Endogenous Renin-Angiotensin System Activation.

  (Nair AR, Agbor LN, Mukohda M, Liu X, Hu C, Wu J, Sigmund CD.) Hypertension. 2018 11;72(5):1227-1235 PMID: 30354810 PMCID: PMC6209120 SCOPUS ID: 2-s2.0-85055599374 10/26/2018

• Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice.

  (Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL.) JCI Insight. 2018 10 04;3(19) PMID: 30282823 PMCID: PMC6237463 SCOPUS ID: 2-s2.0-85063243804 10/05/2018

• A salt-sensing kinase in T lymphocytes, SGK1, drives hypertension and hypertensive end-organ damage.

  (Norlander AE, Saleh MA, Pandey AK, Itani HA, Wu J, Xiao L, Kang J, Dale BL, Goleva SB, Laroumanie F, Du L, Harrison DG, Madhur MS.) JCI Insight. 2017 Jul 06;2(13) PMID: 28679951 PMCID: PMC5499362 07/07/2017