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Staff Collaborate Conference Room

Julian Grosskopf

Julian Grosskopf

G1 Student

Faculty Advisor

Michael Lerch, PhD, Biophysics

Locations

Medical Scientist Training Program

Contact Information

jgrosskopf@mcw.edu

Education

BS, Biochemistry, Biomedical Science, University of Wisconsin-La Crosse, 2019

Research Interests

Structural Biology & Biophysics

Research Experience

Medical College of Wisconsin, 2021-present
Advisor: Michael Lerch, PhD
Project: Exploring the functional role of various lipids and ligands on the conformational topology of G-Protein Coupled Receptors

University of Wisconsin – La Crosse 2016-2019
Advisors: Drs. Todd Weaver & Daniel Grilley
Projects: 1) Performing site-directed alterations to the hemolysin A non polar core to probe for critical residues of structural and functional importance concerning red blood cell lysis. 2) Calculating and extrapolating chemical and thermal stability of SS loop mutants within fumarase C as part of a larger project in exploring the SS loop and its importance in catalysis of fumarate to S-malate.

Publications

Stuttgen GM, Grosskopf JD, Berger CR, et all. (2019). Closed fumarase C active‐site structures reveal SS Loop residue contribution in catalysis. FEBS Letters, 594(2), 337–357. doi: 10.1002/1873-3468.13603

General Interests

Fitness, hockey, coding, and enjoying the outdoors with friends and family