Melanie Gartz, PhD, MS, MHS
- Teresa Patitucci, PhD and Michael W. Lawlor, MD, PhD
MS, Cellular and Developmental Biology, Medical College of Wisconsin, 2014
MHS, Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 2011
BS, Clinical Laboratory Science, University of Wisconsin Milwaukee, 2009
The Lawlor lab has interests in identifying molecular mechanisms underlying genetic disorders including Duchenne muscular dystrophy (DMD) and Nemaline myopathy (NM). We use iPSCs with patient-specific gene mutations to differentiate into cardiomyocytes and skeletal myocytes for modeling disease phenotypes. Prior work has identified oxidative stress and mitochondrial dysfunction as contributing factors to DMD. We are now exploring similar dysfunctional pathways in our in vitro models of NM.
Additionally, I have interests in improving medical and graduate school education at MCW. Under the mentorship of Dr. Teresa Patitucci, I have been training in the M1 class Clinical Human Anatomy (CHA) courses to become an anatomist. I have also participated in lecturing in CHA and the M2 class Foundations of Pathological Processes – Musculoskeletal/Skin.