Pengyuan Liu, PhD

Publications

• Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer.

  (Kelly LM, Barila G, Liu P, Evdokimova VN, Trivedi S, Panebianco F, Gandhi M, Carty SE, Hodak SP, Luo J, Dacic S, Yu YP, Nikiforova MN, Ferris RL, Altschuler DL, Nikiforov YE.) Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4233-8.

• Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer.

  (Morrison CD, Liu P, Woloszynska-Read A, Zhang J, Luo W, Qin M, Bshara W, Conroy JM, Sabatini L, Vedell P, Xiong D, Liu S, Wang J, Shen H, Li Y, Omilian AR, Hill A, Head K, Guru K, Kunnev D, Leach R, Eng KH, Darlak C, Hoeflich C, Veeranki S, Glenn S, You M, Pruitt SC, Johnson CS, Trump DL.) Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E672-81.

• Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence.

  (Liu Y, Liu P, Yang C, Cowley AW Jr, Liang M.) Hypertension. 2014 Apr;63(4):827-38.

• ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer.

  (Leeman-Neill RJ, Kelly LM, Liu P, Brenner AV, Little MP, Bogdanova TI, Evdokimova VN, Hatch M, Zurnadzy LY, Nikiforova MN, Yue NJ, Zhang M, Mabuchi K, Tronko MD, Nikiforov YE.) Cancer. 2014 Mar 15;120(6):799-807.

• EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk.

  (Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL.) Oncogene. 2014 Sep 04;33(36):4464-73.

• Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs.

  (Kriegel AJ, Liu Y, Liu P, Baker MA, Hodges MR, Hua X, Liang M.) Physiol Genomics. 2013 Dec 01;45(23):1144-56.

• Concordant effects of aromatase inhibitors on gene expression in ER+ Rat and human mammary cancers and modulation of the proteins coded by these genes.

  (Lu Y, You M, Ghazoui Z, Liu P, Vedell PT, Wen W, Bode AM, Grubbs CJ, Lubet RA.) Cancer Prev Res (Phila). 2013 Nov;6(11):1151-61.

• Targeting the endothelial progenitor cell surface proteome to identify novel mechanisms that mediate angiogenic efficacy in a rodent model of vascular disease.

  (Kaczorowski CC, Stodola TJ, Hoffmann BR, Prisco AR, Liu PY, Didier DN, Karcher JR, Liang M, Jacob HJ, Greene AS.) Physiol Genomics. 2013 Nov 01;45(21):999-1011.

• DrGaP: a powerful tool for identifying driver genes and pathways in cancer sequencing studies.

  (Hua X, Xu H, Yang Y, Zhu J, Liu P, Lu Y.) Am J Hum Genet. 2013 Sep 05;93(3):439-51.

• Functional genomic assessment of phosgene-induced acute lung injury in mice.

  (Leikauf GD, Concel VJ, Bein K, Liu P, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA Jr, Upadhyay S, Cario C, Di YP, Vuga LJ, Kostem E, Eskin E, You M, Kaminski N, Prows DR, Knoell DL, Fabisiak JP.) Am J Respir Cell Mol Biol. 2013 Sep;49(3):368-83.

• Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat.

  (Yang C, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Skelton M, O'Connor P, Kurth T, Ryan RP, Moreno C, Tsaih SW, Patone G, Hummel O, Jacob HJ, Liang M, Cowley AW Jr.) Hypertension. 2013 Jan;61(1):208-15.

• WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury.

  (Li HH, Li Q, Liu P, Liu Y, Li J, Wasserloos K, Chao W, You M, Oury TD, Chhinder S, Hackam DJ, Billiar TR, Leikauf GD, Pitt BR, Zhang LM.) Am J Respir Cell Mol Biol. 2012 Oct;47(4):528-35.