Staff Collaborate Conference Room
Suma Thareja
SaiSuma Samudrala

Suma Thareja, PhD

M3 Student

Faculty Advisor

  • Aoy Mitchell, PhD, Cell Biology, Neurobiology & Anatomy

Locations

  • Medical Scientist Training Program

Contact Information

Education

BS, Molecular Biology, University of Wisconsin-Madison, 2016

Research Interests

Translating genetic research into cardiac clinical understanding and care. Training at the intersection of medical education and community engagement. Interested in promoting whole health, ensuring health equity, and addressing food insecurity. I am passionate about building pipeline programs for health and science careers.

Research Experience

Medical College of Wisconsin, 2022-2023
Advisor: Jeff Fritz, PhD, MS, MATL
Training Experience: Human-centered design, Quantitative and qualitative research design methods in medical education, Community-driven research

Medical College of Wisconsin, 2018-2022
Advisor: Aoy Mitchell, PhD
Project: Novel KLHL26 variant associated with a familial case of Ebstein’s anomaly and left ventricular non-compaction

University of Wisconsin-Madison, 2013-2015
Advisor: Barry Ganetzky, PhD
Project: A Drosophila genetic screen to find therapeutic targets for radiotherapy, a common treatment for central nervous system malignancies

University of Wisconsin-Madison, 2014-2016
Advisor: Peter Lewis, PhD
Project: Understanding the structural and functional importance of basic patch residues in the highly conserved histone binding domain of the chaperone protein Death-domain associated protein 6 (Daxx)

Publications

Thareja SK, Anfinson M, Cavanaugh M, Kim MS, Lamberton P, Radandt J, Brown R, Liang HL, Stamm K, Afzal MZ, Strande J, Frommelt MA, Lough JW, Fitts RH, Mitchell ME, Tomita-Mitchell A. Altered contractility, Ca2+ transients, and cell morphology seen in a patient-specific iPSC-CM model of Ebstein's anomaly with left ventricular noncompaction. Am J Physiol Heart Circ Physiol. 2023 Jul 1;325(1):H149-H162. doi: 10.1152/ajpheart.00658.2022. Epub 2023 May 19. PMID: 37204873; PMCID: PMC10312315.

Thareja SK, Frommelt MA, Lincoln J, Lough JW, Mitchell ME, Tomita-Mitchell A. A Systematic Review of Ebstein's Anomaly with Left Ventricular Noncompaction. J Cardiovasc Dev Dis. 2022 Apr 13;9(4):115. doi: 10.3390/jcdd9040115. PMID: 35448091; PMCID: PMC9031964.

Kim MS, Fleres B, Lovett J, Anfinson M, Samudrala SSK, Kelly LJ, Teigen LE, Cavanaugh M, Marquez M, Geurts AM, Lough JW, Mitchell ME, Fitts RH, Tomita-Mitchell A. Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome. Front Cell Dev Biol. 2020 Jun 23;8:440. doi: 10.3389/fcell.2020.00440. PMID: 32656206; PMCID: PMC7324479.

Samudrala SSK, North LM, Stamm KD, Earing MG, Frommelt MA, Willes R, Tripathi S, Dsouza NR, Zimmermann MT, Mahnke DK, Liang HL, Lund M, Lin CW, Geddes GC, Mitchell ME, Tomita-Mitchell A. Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction. Mol Genet Genomic Med. 2020 Apr;8(4):e1152. doi: 10.1002/mgg3.1152. Epub 2020 Jan 27. PMID: 31985165; PMCID: PMC7196453.

Geddes GC, Samudrala SS, Earing MG. Neonatal Assessment of Infants with Heterotaxy. Clin Perinatol. 2020 Mar;47(1):171-182. doi: 10.1016/j.clp.2019.10.011. Epub 2019 Oct 31. PMID: 32000924.

Sudmeier LJ, Samudrala SS, Howard SP, Ganetzky B. Persistent Activation of the Innate Immune Response in Adult Drosophila Following Radiation Exposure During Larval Development. G3 (Bethesda). 2015 Sep 1;5(11):2299-306. doi: 10.1534/g3.115.021782. PMID: 26333838; PMCID: PMC4632050. 

Meeting Abstracts

Thareja SK, Espisito J, Ark TA, Yoon J, and Minshew L. How does one become a good (virtuous) physician? The 27th Annual Meeting of the International Association of Medical Science Educators, Cancun, Mexico, June 2023 (Poster).

Thareja SK, Yang X, Mia MR, Upama PB, Torres SP, Cocroft LJ, McGaugeny K, Franco Z, and Whittle J. Southeastern Wisconsin Community-Based Participatory Research using the All of Us. Translational Science 2023, Washington Hilton, Washington, DC, April 2023 (Poster).

Thareja (Samudrala) S, Anfinson M, Cavanaugh M, Kim M, Lamberton P, Radandt J, Brown R, Liang HL, Stamm K, Afzal Z, Strande J, Frommelt MA, Lough JW, Fitts R, Mitchell M, and Tomita-Mitchell A. Decreased Contraction Rate, Altered Calcium Transients, and Increased Proliferation seen in Patient-Specific iPSC-CMs Modeling Ebstein’s Anomaly and Left Ventricular Noncompaction. Weinstein Cardiovascular Development & Regeneration, Palais du Pharo, Marseilles, France, May 2022.

Thareja (Samudrala) S, Anfinson M, Cavanaugh M, Kim M, Lamberton P, Radandt J, Brown R, Liang HL, Stamm K, Afzal Z, Strande J, Frommelt MA, Lough JW, Fitts R, Mitchell M, and Tomita-Mitchell A. Decreased Contraction Rate, Altered Calcium Transients, and Increased Proliferation seen in Patient-Specific iPSC-CMs Modeling Ebstein’s Anomaly and Left Ventricular Noncompaction. Experimental Biology, Pennsylvania Convention Center, Philadelphia, PA. Apr 2022.

Samudrala SS, North L, Stamm K, Earing M, Frommelt MA, Willes R, Tripathi S, Dsouza N, Zimmermann M, Mahnke D, Liang HL, Lund M, Lin C, Geddes GC, Afzal Z, Strande J, Lough JW, Mitchell M, and Tomita-Mitchell A. Novel KLHL26 variant associated with a familial case of Ebstein’s anomaly and left ventricular non-compaction. Weinstein Cardiovascular Development Conference, May 2019.

Samudrala S, North L, Kim M, Strande Jennifer, Zeeshan A, Frommelt MA, Earing M, Lough JW, Mitchell M, and Tomita-Mitchell A. Patient-specific induced pluripotent stem cells to model Ebstein’s anomaly (EA) with left ventricular non-compaction (LVNC). Midwest Pediatric Cardiology Society, St. Louis, MO, September 2017. 

General Interests

Tennis, violin, running, reading, and painting