Yunguang Sun, MD, PhD

Publications

• Neuronatin is a modifier of estrogen receptor-positive breast cancer incidence and outcome.

  (Plasterer C, Tsaih SW, Peck AR, Chervoneva I, O'Meara C, Sun Y, Lemke A, Murphy D, Smith J, Ran S, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Mitchell EP, Bergom C, Joshi A, Auer P, Prokop J, Rui H, Flister MJ.) Breast Cancer Res Treat. 2019 Aug;177(1):77-91.

• The p52 isoform of SHC1 is a key driver of breast cancer initiation.

  (Wright KD, Miller BS, El-Meanawy S, Tsaih SW, Banerjee A, Geurts AM, Sheinin Y, Sun Y, Kalyanaraman B, Rui H, Flister MJ, Sorokin A.) Breast Cancer Res. 2019 06 15;21(1):74.

• Mapping genetic modifiers of radiation-induced cardiotoxicity to rat chromosome 3.

  (Schlaak RA, Frei A, Schottstaedt AM, Tsaih SW, Fish BL, Harmann L, Liu Q, Gasperetti T, Medhora M, North PE, Strande JL, Sun Y, Rui H, Flister MJ, Bergom C.) Am J Physiol Heart Circ Physiol. 2019 Jun 01;316(6):H1267-H1280.

• Loss of Nuclear Localized Parathyroid Hormone-Related Protein in Primary Breast Cancer Predicts Poor Clinical Outcome and Correlates with Suppressed Stat5 Signaling.

  (Tran TH, Utama FE, Sato T, Peck AR, Langenheim JF, Udhane SS, Sun Y, Liu C, Girondo MA, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Palazzo JP, Bibbo M, Auer PW, Flister MJ, Hyslop T, Mitchell EP, Chervoneva I, Rui H.) Clin Cancer Res. 2018 12 15;24(24):6355-6366.

• Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells.

  (Gennaro VJ, Stanek TJ, Peck AR, Sun Y, Wang F, Qie S, Knudsen KE, Rui H, Butt T, Diehl JA, McMahon SB.) Proc Natl Acad Sci U S A. 2018 10 02;115(40):E9298-E9307.

• SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression.

  (Gonyo P, Bergom C, Brandt AC, Tsaih SW, Sun Y, Bigley TM, Lorimer EL, Terhune SS, Rui H, Flister MJ, Long RM, Williams CL.) Oncogene. 2017 12 14;36(50):6873-6883.

• IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling.

  (Wang YA, Sun Y, Palmer J, Solomides C, Huang LC, Shyr Y, Dicker AP, Lu B.) Mol Cancer Res. 2017 07;15(7):896-904.

• Nitrilase 1 modulates lung tumor progression in vitro and in vivo.

  (Wang YA, Sun Y, Le Blanc JM, Solomides C, Zhan T, Lu B.) Oncotarget. 2016 Apr 19;7(16):21381-92.

• Stable and efficient transfection of siRNA for mutated KRAS silencing using novel hybrid nanoparticles.

  (Lakshmikuttyamma A, Sun Y, Lu B, Undieh AS, Shoyele SA.) Mol Pharm. 2014 Dec 01;11(12):4415-24.

• Debio 1143, an antagonist of multiple inhibitor-of-apoptosis proteins, activates apoptosis and enhances radiosensitization of non-small cell lung cancer cells in vitro.

  (Liu N, Tao Z, Blanc JM, Zaorsky NG, Sun Y, Vuagniaux G, Dicker AP, Lu B.) Am J Cancer Res. 2014;4(6):943-51.

• Assessment of M867, a selective caspase-3 inhibitor, in an orthotopic mouse model for non-small cell lung carcinoma.

  (Li B, Blanc JM, Sun Y, Yang L, Zaorsky NG, Giacalone NJ, Torossian A, Lu B.) Am J Cancer Res. 2014;4(2):161-71.

• A novel radiation-induced p53 mutation is not implicated in radiation resistance via a dominant-negative effect.

  (Sun Y, Myers CJ, Dicker AP, Lu B.) PLoS One. 2014;9(2):e87492.