Yunguang Sun, MD, PhD

Publications

• The membrane-associated form of cyclin D1 enhances cellular invasion.

  (Chen K, Jiao X, Ashton A, Di Rocco A, Pestell TG, Sun Y, Zhao J, Casimiro MC, Li Z, Lisanti MP, McCue PA, Shen D, Achilefu S, Rui H, Pestell RG.) Oncogenesis. 2020 Sep 18;9(9):83 PMID: 32948740 PMCID: PMC7501870 SCOPUS ID: 2-s2.0-85091177817 09/20/2020

• Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis.

  (Cho C, Mukherjee R, Peck AR, Sun Y, McBrearty N, Katlinski KV, Gui J, Govindaraju PK, Puré E, Rui H, Fuchs SY.) Oncogene. 2020 Sep;39(38):6129-6137 PMID: 32807917 PMCID: PMC7502515 SCOPUS ID: 2-s2.0-85089539324 08/19/2020

• Malignant cell-specific pro-tumorigenic role of type I interferon receptor in breast cancers.

  (Odnokoz O, Yu P, Peck AR, Sun Y, Kovatich AJ, Hooke JA, Hu H, Mitchell EP, Rui H, Fuchs SY.) Cancer Biol Ther. 2020 Jul 02;21(7):629-636 PMID: 32378445 PMCID: PMC7515508 SCOPUS ID: 2-s2.0-85084376942 05/08/2020

• Acquired Immunity Is Not Essential for Radiation-Induced Heart Dysfunction but Exerts a Complex Impact on Injury.

  (Schlaak RA, Frei A, Fish BL, Harmann L, Gasperetti T, Pipke JL, Sun Y, Rui H, Flister MJ, Gantner BN, Bergom C.) Cancers (Basel). 2020 Apr 16;12(4) PMID: 32316187 PMCID: PMC7226421 04/23/2020

• Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines.

  (Liu N, Wang YA, Sun Y, Ecsedy J, Sun J, Li X, Wang P.) Respir Res. 2019 Oct 23;20(1):230 PMID: 31647033 PMCID: PMC6813099 10/28/2019

• Neuronatin is a modifier of estrogen receptor-positive breast cancer incidence and outcome.

  (Plasterer C, Tsaih SW, Peck AR, Chervoneva I, O'Meara C, Sun Y, Lemke A, Murphy D, Smith J, Ran S, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Mitchell EP, Bergom C, Joshi A, Auer P, Prokop J, Rui H, Flister MJ.) Breast Cancer Res Treat. 2019 Aug;177(1):77-91 PMID: 31165373 SCOPUS ID: 2-s2.0-85066986189 06/06/2019

• The p52 isoform of SHC1 is a key driver of breast cancer initiation.

  (Wright KD, Miller BS, El-Meanawy S, Tsaih SW, Banerjee A, Geurts AM, Sheinin Y, Sun Y, Kalyanaraman B, Rui H, Flister MJ, Sorokin A.) Breast Cancer Res. 2019 06 15;21(1):74 PMID: 31202267 PMCID: PMC6570928 SCOPUS ID: 2-s2.0-85067234098 06/17/2019

• Mapping genetic modifiers of radiation-induced cardiotoxicity to rat chromosome 3.

  (Schlaak RA, Frei A, Schottstaedt AM, Tsaih SW, Fish BL, Harmann L, Liu Q, Gasperetti T, Medhora M, North PE, Strande JL, Sun Y, Rui H, Flister MJ, Bergom C.) Am J Physiol Heart Circ Physiol. 2019 06 01;316(6):H1267-H1280 PMID: 30848680 PMCID: PMC6620678 SCOPUS ID: 2-s2.0-85066837925 03/09/2019

• Loss of Nuclear Localized Parathyroid Hormone-Related Protein in Primary Breast Cancer Predicts Poor Clinical Outcome and Correlates with Suppressed Stat5 Signaling.

  (Tran TH, Utama FE, Sato T, Peck AR, Langenheim JF, Udhane SS, Sun Y, Liu C, Girondo MA, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Palazzo JP, Bibbo M, Auer PW, Flister MJ, Hyslop T, Mitchell EP, Chervoneva I, Rui H.) Clin Cancer Res. 2018 12 15;24(24):6355-6366 PMID: 30097435 SCOPUS ID: 2-s2.0-85058487046 08/12/2018

• Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells.

  (Gennaro VJ, Stanek TJ, Peck AR, Sun Y, Wang F, Qie S, Knudsen KE, Rui H, Butt T, Diehl JA, McMahon SB.) Proc Natl Acad Sci U S A. 2018 10 02;115(40):E9298-E9307 PMID: 30224477 PMCID: PMC6176615 SCOPUS ID: 2-s2.0-85054360749 09/19/2018

• SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression.

  (Gonyo P, Bergom C, Brandt AC, Tsaih SW, Sun Y, Bigley TM, Lorimer EL, Terhune SS, Rui H, Flister MJ, Long RM, Williams CL.) Oncogene. 2017 12 14;36(50):6873-6883 PMID: 28806394 PMCID: PMC5730474 SCOPUS ID: 2-s2.0-85038242723 08/15/2017

• IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling.

  (Wang YA, Sun Y, Palmer J, Solomides C, Huang LC, Shyr Y, Dicker AP, Lu B.) Mol Cancer Res. 2017 07;15(7):896-904 PMID: 28330997 03/24/2017