Research Lab Bench


Matt Scaglione

Matt Scaglione, PhD

Assistant Professor


  • Biochemistry
    TBRC C1875


PhD, Saint Louis University School of Medicine, 2007
BS, McKendree University, 2001


K. Matthew Scaglione received his Bachelor of Science degree in Biology from McKendree University in 2001 and his Doctorate in Biochemistry from Saint Louis University School of Medicine in 2007 where his research focused on ubiquitin pathways in cancer. He performed postdoctoral studies at the University of Michigan School of Medicine from 2007 until 2013 investigating the role of protein quality control pathways in neurodegenerative diseases. During his postdoctoral studies Dr. Scaglione was awarded a F32 (Ruth L. Kirschstein National Research Service Award) and a NIH K99/R00 (Pathway to Independence Award). Dr. Scaglione joined the faculty of the Medical College of Wisconsin in 2013.

View more information about the Scaglione Lab

Honors and Awards

Ruth L. Kirschstein National Research Service Award Winner
Pathway to Independence Award winner

Research Interests

The Scaglione lab investigates protein aggregation in neurodegenerative diseases. The lab has two main areas of focus, the first focuses on developing strategies to enhance neuroprotective protein quality control pathways. The second focuses on understanding how the social amoeba, Dictyostelium discoideum, naturally resists protein aggregation. Our ultimate goal is to develop therapeutics that can be used to treat neurodegenerative diseases.