
Jesse G. Meyer, PhD
Assistant Professor
Locations
- Biochemistry
BSB 376E
Contact Information
General Interests
Education
MS, Chemistry, University of California, San Diego, 2012
BS, Biochemistry - Chemistry Minor, University of Minnesota - Twin Cities, 2009
Biography
Jesse received his Bachelor of Science degree in Biochemistry from the University of Minnesota in 2009. He then worked as a junior scientist in a plant metabolomics lab for a year while applying for graduate school. He began his PhD studies in Chemistry at the University of California, San Diego, and graduated in spring of 2015. In San Diego, he developed new methods to increase the observable proteome. To learn more about the biology of metabolism and aging, he started a postdoctoral position at the Buck Institute for Research on Aging in 2015. During this time, Jesse published a number of papers on methods for study of protein acylation. In summer 2018, he left the Buck Institute to do a second postdoctoral fellowship at the University of Wisconsin, Madison. Here he developed skills in machine learning and built a method for ultrafast proteome analysis. He started as Assistant Professor at the Medical College of Wisconsin in August 2020.
Dr. Meyer teaches in the following graduate-level courses: Techniques in Molecular and Cellular Biology (16242), Biophysical Techniques in Biochemistry (03226/02226).
Research Experience
- Acetyl Coenzyme A
- Acetylation
- Acylation
- Amino Acid Sequence
- Energy Metabolism
- Escherichia coli
- Glucose
- Liver
- Lysine
- Machine Learning
- Mass Spectrometry
- metabolism
Methodologies and Techniques
- Acetylation
- Acylation
- Mass Spectrometry
- Mitochondria
- Mitochondrial Proteins
- Peptides
- Protein Processing, Post-Translational
- Proteins
- Proteome
- Proteomics
- Serine Endopeptidases
- Sirtuins
Publications
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Peptide Correlation Analysis (PeCorA) Reveals Differential Proteoform Regulation.
(Dermit M, Peters-Clarke TM, Shishkova E, Meyer JG.) J Proteome Res. 2021 04 02;20(4):1972-1980 PMID: 33325715 12/17/2020
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Large-Scale Multi-omic Analysis of COVID-19 Severity.
(Overmyer KA, Shishkova E, Miller IJ, Balnis J, Bernstein MN, Peters-Clarke TM, Meyer JG, Quan Q, Muehlbauer LK, Trujillo EA, He Y, Chopra A, Chieng HC, Tiwari A, Judson MA, Paulson B, Brademan DR, Zhu Y, Serrano LR, Linke V, Drake LA, Adam AP, Schwartz BS, Singer HA, Swanson S, Mosher DF, Stewart R, Coon JJ, Jaitovich A.) Cell Syst. 2021 01 20;12(1):23-40.e7 PMID: 33096026 PMCID: PMC7543711 10/24/2020
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(Meyer JG.) Methods Mol Biol. 2021;2259:297-308 PMID: 33687723 03/10/2021
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Quantitative shotgun proteome analysis by direct infusion.
(Meyer JG, Niemi NM, Pagliarini DJ, Coon JJ.) Nat Methods. 2020 12;17(12):1222-1228 PMID: 33230323 PMCID: PMC8009190 11/25/2020
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(Gut P, Matilainen S, Meyer JG, Pällijeff P, Richard J, Carroll CJ, Euro L, Jackson CB, Isohanni P, Minassian BA, Alkhater RA, Østergaard E, Civiletto G, Parisi A, Thevenet J, Rardin MJ, He W, Nishida Y, Newman JC, Liu X, Christen S, Moco S, Locasale JW, Schilling B, Suomalainen A, Verdin E.) Nat Commun. 2020 11 23;11(1):5927 PMID: 33230181 PMCID: PMC7684291 11/25/2020
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(Meyer JG, Garcia TY, Schilling B, Gibson BW, Lamba DA.) Sci Rep. 2019 10 28;9(1):15440 PMID: 31659173 PMCID: PMC6817852 10/30/2019
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(Meyer JG, Liu S, Miller IJ, Coon JJ, Gitter A.) J Chem Inf Model. 2019 10 28;59(10):4438-4449 PMID: 31518132 PMCID: PMC6819987 09/14/2019
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(Softic S, Meyer JG, Wang GX, Gupta MK, Batista TM, Lauritzen HPMM, Fujisaka S, Serra D, Herrero L, Willoughby J, Fitzgerald K, Ilkayeva O, Newgard CB, Gibson BW, Schilling B, Cohen DE, Kahn CR.) Cell Metab. 2019 10 01;30(4):735-753.e4 PMID: 31577934 PMCID: PMC7816129 10/03/2019
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Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.
(Wang G, Meyer JG, Cai W, Softic S, Li ME, Verdin E, Newgard C, Schilling B, Kahn CR.) Mol Cell. 2019 05 16;74(4):844-857.e7 PMID: 31000437 PMCID: PMC6525068 04/20/2019
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(Christensen DG, Meyer JG, Baumgartner JT, D'Souza AK, Nelson WC, Payne SH, Kuhn ML, Schilling B, Wolfe AJ.) mBio. 2019 04 09;10(2) PMID: 30967468 PMCID: PMC6456757 04/11/2019
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(Meyer JG.) Methods Protoc. 2019 Mar;2(1) PMID: 31008411 PMCID: PMC6469856 04/23/2019
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High-Resolution Mass Spectrometry to Identify and Quantify Acetylation Protein Targets.
(Schilling B, Meyer JG, Wei L, Ott M, Verdin E.) Methods Mol Biol. 2019;1983:3-16 PMID: 31087289 PMCID: PMC6825508 05/16/2019