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MCW Cancer Center Pilot Grants

October 2020 RFA

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In an effort to advance cancer research with a goal of improving the health of Wisconsin citizens, the Medical College of Wisconsin Cancer Center is seeking proposals for cancer research projects.

Sources of pilot funding include ACS-IRG, Cancer Crush and other philanthropic funds. Project dates commence March 2021.

MCWCC Pilot Grants are using a database system to collect your cover sheet and annual progress reports. Begin the process. You will be prompted to log in to the Faculty Collaboration Database.

Pilot Grant Funding Opportunities

Multiple awards are available in each category.

 

RFA Code

ACS-IRG Pilot Award

1-year award for up to $30,000 with the potential to obtain a

1-year supplement for up to $20,000 with evidence of an extramural funding application in progress

 

ACS

Team Science Award

2-year award for up to $150,000 per year

 

 

TEAM

Idea Award

1-year for up to $50,000

 IDEA

Equipment and Technology Award

Open to Cancer Center Shared Resource Directors ONLY

 EQUIP

NGS-Based Pilot Projects-Sequencing, Bioinformatics, and Analysis Award

Sequencing through Bioinformatics projects will receive up to $15,000 for GSPMC services

Bioinformatics-only projects will receive up to $5,000 for GSPMC services

 GSPMC

Pre-Clinical Concept Award

1-year up to $50,000

 PRE CLIN

Clinical Concept Award

2-year up to $150,000

 CLIN

Special areas of emphasis for BSC and PH

  • Multi PI/Collaborative Science
  • Disparity-related

Basic Eligibility Requirements 

Applicants may only submit one proposal per funding mechanism. 

Applicants may apply to more than one funding mechanism as long as the proposals are scientifically distinct.

Principal Investigator (PI) Eligibility: MCW tenure-track faculty (including joint appointments) with full-time or full professional effort status are eligible to serve as principal investigators; adjunct and part-time faculty are NOT eligible to apply for these awards.

Deadlines

  • December 1, 2020 5:00 pm CT. Application Due to MCW Cancer Center by email to Nicole Davis.

Note: MCW has adopted a new process for internal grant submissions. Applications will not be entered into eBridge unless they are chosen for funding. Research Program Coordinator will assist you with that process if your proposal is selected. 

American Cancer Society Institutional Research Grant (ACS-IRG): The purpose of the ACS-IRG Award is to support the development of exceptional cancer-related research projects for junior faculty members who are in the process of establishing independent cancer research programs, thus, advancing the objectives of the MCW Cancer Center. ACS distributes $30,000 awards for a one-year award period. Awardees are eligible for supplement funding. With keeping the end-result in mind, the goal of the individual ACS-IRG seed award is to generate pilot data to successfully compete for and obtain extramural peer-reviewed funding.

Team Science Award: The purpose of this RFA is to stimulate the development of high-quality, multi-investigator (minimum of three) program project grants that will move forward to extramurally funded grant awards. Projects with translational potential are encouraged, but not mandatory. Inter-programmatic and inter-institutional teams are also highly encouraged. MCW CC leadership anticipates distributing awards up to $150,000 per year for up to two years.
 
Idea Award: The purpose of this RFA is to stimulate the development of high-quality, innovative cancer research projects from basic to clinical and population science that will move forward to extramurally funded grant awards. Idea Awards provide early funding support for high-risk, high-payoff research for which external grants are difficult to obtain. While preliminary data is not required, it is always a positive asset to an application; it is acceptable that the premise for a proposal is grounded in theory. MCW Cancer Center (CC) leadership anticipates distributing awards of up to $50,000 for one year without the option to renew.
 
Equipment and Technology Award: The purpose of the MCW Cancer Center’s (CC) Equipment and Technology Award (ETA) is to provide a mechanism for replacing aging, obsolete or damaged research instrumentation, or to acquire new research equipment that represents the latest advances in the field. Support for development of new technologies or data infrastructure, beyond equipment purchases, will also be considered for funding by this mechanism. The overall aim of the program is to provide the state-of-the-art multi-user instrumentation and technologies necessary to support the research goals of cancer center investigators. This mechanism is open to Shared Resource Directors only.
 
NGS-Based Pilot Projects - Sequencing, Bioinformatics, and Analysis: To advance precision oncology and the molecular understanding of cancer, the MCW Cancer Center (CC), in partnership with the Genomic Sciences and Precision Medicine Center (GSPMC), is inviting proposals for small-scale research projects that utilize any combination of the genomic, transcriptomic or epigenomic technologies and bioinformatics platforms available in the GSPMC.  Responsive proposals will describe projects that either improve our understanding of cancer initiation, progression or therapeutic resistance or show promise to improve cancer prevention, early detection, diagnosis or treatment.
 
Pre-Clinical Concept Award: Clinical trials help develop new ways to prevent and treat cancer, providing participating patients with access to the most advanced treatments. The MCW Cancer Center (CC) provides support for development of pre-clinical concepts based on discoveries made at the CC. CC leadership anticipates distributing awards of up to $50,000 for one year.

Clinical Concepts Award:
Clinical trials help develop new ways to prevent, diagnose and treat cancer, providing participating individuals with access to the most advanced treatments. The MCW Cancer Center (CC) provides support for the development of interventional trial concepts (related to prevention, diagnosis, and treatment) based on discoveries made at MCW.
 
Note: Applications for Multi PI Grants and projects to explore cancer disparities are encouraged.

Please click on the sections below to access forms and further instructions. If you have any questions or need support, contact Nicole Davis.

Instructions, Forms, Deadlines and Resources

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Deadlines

The Medical College of Wisconsin Cancer Center is seeking pilot grant proposals for cancer-relevant projects: 

 

RFA Released

Application Due to Cancer Center

Award Start Date

October 1

December 1

March 1

Deadlines

December 1, 2020 5:00 pm CT. Application Due to MCW Cancer Center by email to Nicole Davis at nmdavis@mcw.edu

Note: MCW has adopted a new process for internal grant submissions.  Applications will not be entered into eBridge unless they are chosen for funding.  Research Program Coordinator will assist you with that process if your proposal is selected.

Eligibility
Eligibility Requirements  

Applicants may only submit one proposal per funding mechanism.

Applicants may apply to more than one funding mechanism as long as the proposals are scientifically distinct.

Principal Investigator (PI) Eligibility: MCW tenure-track faculty (including joint appointments) with full-time or full professional effort status are eligible to serve as principal investigators; adjunct and part-time faculty are NOT eligible to apply for these awards.

Mentorship Committee: All applicants who have not had a previously funded peer-reviewed grant from the NIH or extramural organization must have a mentorship committee to assist in reading and providing feedback on the proposal. A mentorship committee must include a minimum of two faculty members. A letter of support from at least one of the mentorship committee members is required.

Budget Guidelines

Budget Guidelines (see instructions for specific details)

  • PI effort must be cost shared.
  • No Subcontracts are allowed without prior approval.
  • Travel is capped at $2,000 for PI travel to a scientific meeting to present data.

Budget: List direct costs only; indirect costs are not allowed. Direct costs should align with award goals and objectives. Costs that have NOT been identified and approved through the application process must be requested as a re-budget prior to being incurred or the cost is considered unallowable.

Bridge Funding Not Allowed: Funding cannot be used as “bridge funding” for lapsed grants from any extramural source and is intended to be used solely for new projects.

Review Criteria

Grant Writing Resources

You are strongly encouraged to take advantage of the available resources for developing and writing research proposals. Resources include Mentoring Committees, Research Program Leaders, Cancer Center Senior Leadership, and Department Chairs. 

Review Criteria

Significance: Does the project address an important problem or a critical barrier to progress in the field? If the aims of the project are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? How will successful completion of the aims change the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field?

Investigator: Are the PD/PIs, collaborators, and other researchers well suited to the project? If they are early stage investigators, new investigators, or in the early stages of independent careers, do they have appropriate experience and training? If established, have they demonstrated an ongoing record of accomplishments that have advanced their field(s)? If the project is collaborative or multi-PD/PI, do the investigators have complementary and integrated expertise; are their leadership approach, governance and organizational structure appropriate for the project? Reminder: submit Biosketches for all key personnel.

Innovation: Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? Are the concepts, approaches or methodologies, instrumentation, or interventions novel to one field of research or novel in a broad sense? Is a refinement, improvement, or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions proposed?

Approach: Are the overall strategy, methodology, and analyses well-reasoned and appropriate to accomplish the specific aims of the project? Are potential problems, alternative strategies, and benchmarks for success presented? If the project is in the early stages of development, will the strategy establish feasibility, and will particularly risky aspects be managed? If the project involves clinical research, are the plans for 1) protection of human subjects from research risks, and 2) inclusion of minorities and members of both sexes/genders, as well as the inclusion of children, justified in terms of the scientific goals and research strategy proposed?

Environment: Will the scientific environment in which the work will be done contribute to the probability of success? Is the institutional support, equipment and other physical resources available to the investigators adequate for the project proposed? Will the project benefit from unique features of the scientific environment, subject populations, or collaborative arrangements? Reminder: submit your one-page Facilities component with your application.

Extramural Funding Potential: How will the completion of the aims of the proposed project support an external grant proposal? What is the likelihood that the proposed project will generate resultant preliminary data for submitting a strong proposal for peer-reviewed extramural funding?

Does proposal address any of the special areas of emphasis for BSC and PH:  
Multi PI/Collaborative Science
Disparity-related

Additional elements:

Return on Investment: Used only for applicants with prior Cancer Center Pilot Grants. Reviewers will provide an evaluation of the applicants return on investment (peer-reviewed publications and extramural grants) from previously awarded Cancer Center Pilot Grants using the information submitted by the applicant on Form D.

Acknowledgement: Award recipients must acknowledge the MCW Cancer Center and funding support from philanthropic sources (such as the ACS, Wisconsin Breast Cancer Showhouse, Advancing a Healthier Wisconsin, or the State of Wisconsin Tax Check-Off Program for Breast or Prostate Cancer Research) in any publications, scientific abstracts (where permitted), posters at scientific meetings, press releases or other media communications, and Internet-based communications. Award letters will indicate the appropriate funding source to acknowledge.