About the Study
There is a much greater risk for anal cancer among gay and bisexual men, especially gay and bisexual men who are HIV-positive. But we don’t know the best way for people to get screened.
The PAC Study aims to change that. This study will find ways to detect anal cancer earlier, when it’s much easier to treat.
We will enroll gay and bisexual men and transgender women into a one-year study. Participants will receive up to $130 to help us learn better ways to find anal cancer.
This study is funded by the National Cancer Institute at the National Institutes of Health. It is being led by researchers at the Medical College of Wisconsin in partnership with community-based organizations, community clinics, and other universities.
If you would like more information about the study, please contact us.
Click on each + to take the eligibility survey, learn more about the study team, and find out more about anal cancer and screening.
See if you are eligible to participate in the PAC study.
If you don't want to participate in the study, but would like to learn more about anal cancer, you can use the links below to access resources on anal cancer.
Meet the PAC study team at the Medical College of Wisconsin:
Alan Nyitray, PhD, Principal Investigator and Professor, MCW Cancer Center and Center for AIDS Intervention Research
Alan Nyitray is an Associate Professor of Epidemiology at the Medical College of Wisconsin in Milwaukee. His research has focused on the natural history of anal HPV infection and, most recently, anal cancer screening. The anal HPV epidemiology research has included studies with gay, bisexual, and other men who have sex with men, heterosexual couples, and heterosexual men. His current research assesses protocols for anal precancer and cancer screening. He has published more the 50 peer-reviewed papers on these topics and is funded by the National Cancer Institute. Prior to his HPV research, Nyitray delivered HIV prevention in a service capacity for 15 years.
Christopher Ajala, MD, MPH, Clinical Research Coordinator
Christopher is a clinical researcher who supports Dr. Nyitray, coordinating the PAC anal cancer screening studies at MCW. Christopher has content expertise in scientific principles and research methodology. He has a master’s degree in Public Health Administration and Policy from the University of Minnesota School of Public Health, Twin Cities. In addition to his public health experience, he is a trained physician from Nigeria.
Bridgett Brezinski, MA (Master of Arts in Health Communication), Community Research Assistant
Bridgett is a Community Research Assistant III with Dr. Alan Nyitray. She supports the PAC studies looking at anal cancer prevention, working at the MCW Cancer Center, the Center for AIDS Intervention Research, and with five Milwaukee clinics, supporting participants and the community. Bridgett’s undergraduate background is in Corporate Communication and Women’s Studies. She also holds a master’s degree in Health Communication with a research focus on sexual health and physician-patient communication.
Research publications, presentations, and other media.
PAC Study Principal Investigator Dr. Alan Nyitray featured for his work with the LGBTQ+ community with colleague Dr. Malika Siker.
PAC Study Coordinator Christopher Ajala, MD, MPH, presents a scientific poster on the PAC study methodology titled, "Protocol of the Prevent Anal Cancer Study of Self-Swabbing and Novel Biomarkers," at the MCW Cancer Center 2019 Scientific Retreat.
PAC Study Principal Investigator Dr. Alan Nyitray presents his talk titled, "Novel Opportunities for Anal Cancer Screening Among Men" at the MCW Cancer Center 2019 Scientific Retreat.
Contact Us & Get Involved
For general information contact:
PAC Study, Medical College of Wisconsin Cancer Center: PACStudy@mcw.edu
Or you can contact the study team at the Medical College of Wisconsin:
Study Coordinator: Christopher Ajala, MD, MPH, firstname.lastname@example.org or (414) 882-0036
Research Assistant: Bridgett Brzezinski, MA, email@example.com, (414) 882-0131
Principal Investigator: Alan Nyitray, PhD, firstname.lastname@example.org or (414) 805-3312