Recent Publications

• Cancer therapy-induced cardiovascular toxicity: old/new problems and old drugs.

  (Beyer AM, Bonini MG, Moslehi J.) Am J Physiol Heart Circ Physiol. 2019 Jul 01;317(1):H164-H167 PMID: 31172808 PMCID: PMC6692734 SCOPUS ID: 2-s2.0-85069238135 06/08/2019

• Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)-Dependent Pulmonary Arterial Hypertension.

  (Oliveira SDS, Chen J, Castellon M, Mao M, Raj JU, Comhair S, Erzurum S, Silva CLM, Machado RF, Bonini MG, Minshall RD.) Arterioscler Thromb Vasc Biol. 2019 06;39(6):1191-1202 PMID: 30943774 SCOPUS ID: 2-s2.0-85066511992 04/05/2019

• Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.

  (Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, Nomura DK, Bonini MG, Locasale JW, Rosner MR.) Nature. 2019 04;568(7751):254-258 PMID: 30842661 PMCID: PMC6698916 SCOPUS ID: 2-s2.0-85064269030 03/08/2019

• Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells.

  (Chen Z, D S Oliveira S, Zimnicka AM, Jiang Y, Sharma T, Chen S, Lazarov O, Bonini MG, Haus JM, Minshall RD.) Mol Biol Cell. 2018 05 15;29(10):1190-1202 PMID: 29563255 PMCID: PMC5935069 SCOPUS ID: 2-s2.0-85047085775 03/23/2018

• Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice.

  (Ganini D, Santos JH, Bonini MG, Mason RP.) Cell Chem Biol. 2018 04 19;25(4):413-425.e6 PMID: 29398562 PMCID: PMC5910218 SCOPUS ID: 2-s2.0-85045742134 02/06/2018

• Environmental Toxicant Exposures and Type 2 Diabetes Mellitus: Two Interrelated Public Health Problems on the Rise.

  (Bonini MG, Sargis RM.) Curr Opin Toxicol. 2018 Feb;7:52-59 PMID: 29392186 PMCID: PMC5788318 02/03/2018

• Dicarbonyl stress and glyoxalase enzyme system regulation in human skeletal muscle.

  (Mey JT, Blackburn BK, Miranda ER, Chaves AB, Briller J, Bonini MG, Haus JM.) Am J Physiol Regul Integr Comp Physiol. 2018 02 01;314(2):R181-R190 PMID: 29046313 PMCID: PMC5867671 SCOPUS ID: 2-s2.0-85043582559 10/20/2017

• Nitric oxide donor [Ru(terpy)(bdq)NO] induces uncoupling and phosphorylation of endothelial nitric oxide synthase promoting oxidant production.

  (Potje SR, Chen Z, Oliveira SDS, Bendhack LM, da Silva RS, Bonini MG, Antoniali C, Minshall RD.) Free Radic Biol Med. 2017 11;112:587-596 PMID: 28899725 PMCID: PMC5647835 SCOPUS ID: 2-s2.0-85029361713 09/14/2017

• Mitochondria targeting by environmental stressors: Implications for redox cellular signaling.

  (Blajszczak C, Bonini MG.) Toxicology. 2017 11 01;391:84-89 PMID: 28750850 PMCID: PMC5939563 SCOPUS ID: 2-s2.0-85028334909 07/29/2017

• Manganese superoxide dismutase (SOD2): is there a center in the universe of mitochondrial redox signaling?

  (Zou X, Ratti BA, O'Brien JG, Lautenschlager SO, Gius DR, Bonini MG, Zhu Y.) J Bioenerg Biomembr. 2017 Aug;49(4):325-333 PMID: 28616679 SCOPUS ID: 2-s2.0-85020745291 06/16/2017

• Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPR to promote metastasis.

  (Kenny TC, Hart P, Ragazzi M, Sersinghe M, Chipuk J, Sagar MAK, Eliceiri KW, LaFramboise T, Grandhi S, Santos J, Riar AK, Papa L, D'Aurello M, Manfredi G, Bonini MG, Germain D.) Oncogene. 2017 08;36(31):4393-4404 PMID: 28368421 PMCID: PMC5542861 SCOPUS ID: 2-s2.0-85016955700 04/04/2017

• Allele-specific interaction between glutathione peroxidase 1 and manganese superoxide dismutase affects the levels of Bcl-2, Sirt3 and E-cadherin.

  (Ekoue DN, Bera S, Ansong E, Hart PC, Zaichick S, Domann FE, Bonini MG, Diamond AM.) Free Radic Res. 2017 Jun;51(6):582-590 PMID: 28587495 PMCID: PMC5683088 SCOPUS ID: 2-s2.0-85021841587 06/08/2017