Fernando Santos-Pinheiro, MD
- Froedtert Hospital
- Cancer Center - Froedtert Hospital
- Cancer Center - Froedtert Menomonee Falls Hospital
- Cancer Center - Drexel Town Square Health Center
- English, Portuguese
- MD - Doctor of Medicine
- Brain Neoplasms
- Transcranial Magnetic Stimulation
Non-Convulsive Status Epilepticus in cancer patients with altered mental status.
Collaborator: John F de Groot MD
Non-convulsive status epilepticus (NCSE) is a potentially treatable etiology of unexplained altered mental status (AMS) in cancer patients. NCSE may be under-recognized clinically making electroencephalogram (EEG) essential for diagnosis. The purpose of this study was to determine the incidence of NCSE among patients with cancer undergoing inpatient neurology consultation for AMS, and to characterize their clinical features. (collecting data)
The molecular characteristics of long-term survivors with glioblastoma who have been submitted to maintenance therapy with isotretinoin.
Collaborator: Alfred Yung, MD
A deep sequencing molecular analysis of long-term glioblastoma survivors (5 years or longer) who have been submitted to maintenance isotretinoin after standard therapy. (analyzing tissue)
Resection of the enhancing portion of the tumor vs extended resection in high-grade gliomas. What should we learn from Epilepsy Surgery concepts.
Collaborator: Sujit Prabhu, MD
Resection of the enhancing portion of high-grade gliomas is considered to be the best practice for the management of highly morbid and recurrent tumors. Nevertheless, often times tumors localized to the non-dominant hemisphere may allow the surgeon to extend the resection to a partial or total lobectomy as opposed to stay restricted to the enhancing portion. We aim to investigate the use electrophysiologic (scalp and intra-operative EEG monitoring, ECoG) and radiographic (connectome, MRS) tools to determine the functional status of the peri- lesional brain parenchyma. (collecting data)
The cause-effect relationship between discontinuation of antiepileptic drugs after surgical resection of low grade gliomas and breakthrough seizures.
Collaborator: Merry Chen, MD
Retrospective review of seizure outcome based on initiation and discontinuation of AED’s in low-grade glioma patients presenting or not with seizures prior to tumor diagnosis.
Multidisciplinary Management of Pituitary Carcinoma – The MD Anderson Cancer Center experience from 1994 through 2016.
Collaborator: Carlos Kamiya Matsuoka, MD
This will be the largest case series of pituitary carcinoma available in literature. A total of 15 patients treated and followed up long-term in this institution will be presented. A review of the literature will follow.
(Santos-Pinheiro F, Penas-Prado M, Kamiya-Matsuoka C, Waguespack SG, Mahajan A, Brown PD, Shah KB, Fuller GN, McCutcheon IE.) Eur J Endocrinol. 2019 Oct;181(4):397-407 PMID: 31349217 SCOPUS ID: 2-s2.0-85072212414 07/28/2019
(Santos-Pinheiro F, Park M, Liu D, Kwong LN, Cruz S, Levine NB, O'Brien BJ, Chen M.) Neurooncol Pract. 2019 May;6(3):209-217 PMID: 31386048 PMCID: PMC6656314 SCOPUS ID: 2-s2.0-85067638717 08/07/2019
(Majd NK, Metrus NR, Santos-Pinheiro F, Trevino CR, Fuller GN, Huse JT, Chung C, Ketonen L, Anderson MD, Penas-Prado M.) Cancer Genet. 2019 02;231-232:41-45 PMID: 30803556 SCOPUS ID: 2-s2.0-85060025437 02/26/2019
(Fernando Santos-Pinheiro, Mingjeong Park, Diane Liu, Lawrence N Kwong, Savannah Cruz, Nicholas B Levine, Barbara J O'Brien, Merry Chen .) Neuro-Oncology Practice. 07/09/2018
(Christofolini DM, Cordts EB, Santos-Pinheiro F, Kayaki EA, Dornas MCF, Santos MC, Bianco B, Barbosa CP.) Einstein (Sao Paulo). 2017 Jul-Sep;15(3):269-272 PMID: 29091146 PMCID: PMC5823038 SCOPUS ID: 2-s2.0-85038129792 11/02/2017
(Pinheiro FS, Rothner AD, Moodley M, Zahka KG.) J Child Neurol. 2015 Oct;30(11):1537-43 PMID: 25694465 02/20/2015
(Santos-Pinheiro F, Li Y.) J Clin Neuromuscul Dis. 2015 Mar;16(3):125-30 PMID: 25695917 SCOPUS ID: 2-s2.0-84924158121 02/20/2015