Currently Enrolling Study
Retrophin CTX Prevalence Cataract Study
Purpose of study:
The purpose of this study is to understand how common a condition called CTX is in people who have been diagnosed with cataract, or a clouding of the lens, in both eyes when they were younger.
What is CTX?
CTX is a rare but treatable condition where people do not make bile acids normally. CTX may be associated with cataracts that were diagnosed at a young age and has an unknown cause.
What is involved in this study?
Potential study participants will be asked to come to the Froedtert & the Medical College of Wisconsin Eye Institute for a one-time study visit, which should take about one hour. During the visit, you will be asked to review a consent form that describes the study in further detail and if you decided to join the study, you will be asked to sign the consent form. A health history, current medications taken and health history of your family members will be obtained. Additionally, 1 tube of blood and a urine sample will be taken to test for certain substances that may indicate you have CTX.
A total of about 500 people, both children and adults are expected to participate in this study nationally, including about 30 at Froedtert & the Medical College of Wisconsin Eye Institute and Children’s Hospital of Wisconsin.
Research participants will receive a $50 stipend for the study visit.
You may be eligible to participate in this study if you meet these criteria.
- A doctor has told you that you have cataracts in both eyes, and the cause is unknown.
- You were between 2 to 21 years old at the time you were diagnosed with cataracts in both eyes.
Additional information about the Retrophin CTX Prevalence Cataract study can be found at ClinicalTrials.gov.
Contact Katie McKenney with questions. (414) 955-7866 or email
IRB Approval: CHW16/127, 10/07/2017
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