Ophthalmology & Visual Sciences at the Eye Institute

Ophthalmology and Visual Sciences

Currently Enrolling Study

Development of Patient-Specific Retinal Cells from Induced Pluripotent Stem Cell for Generating Human Retinal Models of Eye Diseases

Purpose of study:
This research study is being conducted to gain more information on how inherited eye conditions cause certain cells to die and lead to vision loss. We intend to collect skin specimens from individuals with genetically confirmed inherited retinal degenerations (IRD) OR individuals who are known carriers of an IRD. Researchers will use skin cells to derive induced pluripotent stem cells (iPSC), which will be studied in a laboratory.

What are inherited retinal degenerations?
Inherited retinal degenerations are diseases that run in families and lead to the deterioration of the retina and vision loss. This deterioration is caused by the death of the light-sensing cells that make up the retina.

What is involved?
The study consists of one visit that will take about one hour. At this visit, we will perform a skin punch biopsy, which involves removing a small “punch” of skin from your arm (about half the size of a pencil eraser), and a review of medical and ocular history.

Research volunteers will be compensated $50 for the completion of the study visit.

You may be eligible to participate in this study if you meet these criteria.

  • You are 5 years or older.
  • You have had your blood genetically tested to confirm you have an inherited retinal degeneration OR you are a known carrier of an inherited retinal degeneration.

More Information:

Contact Katie McKenney with questions. (414) 955-7866 or email

IRB Approval: PRO00031021, 11/14/2018