Pathology & Laboratory Medicine

Publications

• Cytotoxic CD8-positive T-lymphocyte infiltration in the lungs as a histological pattern of SARS-CoV-2 pneumonitis.

  (Puzyrenko A, Felix JC, Ledeboer NA, Sun Y, Rui H, Sheinin Y.) Pathology. 2022 Jun;54(4):404-408 PMID: 34836647 PMCID: PMC8572726 SCOPUS ID: 2-s2.0-85119915379 11/28/2021

• Spatial Metrics of Interaction between CD163-Positive Macrophages and Cancer Cells and Progression-Free Survival in Chemo-Treated Breast Cancer.

  (Maisel BA, Yi M, Peck AR, Sun Y, Hooke JA, Kovatich AJ, Shriver CD, Hu H, Nevalainen MT, Tanaka T, Simone N, Wang LL, Rui H, Chervoneva I.) Cancers (Basel). 2022 Jan 08;14(2) PMID: 35053472 PMCID: PMC8773496 01/22/2022

• RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.

  (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P.) Cell Rep. 2021 11 02;37(5):109934 PMID: 34731628 PMCID: PMC8675433 SCOPUS ID: 2-s2.0-85118477211 11/04/2021

• Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth.

  (Geethadevi A, Nair A, Parashar D, Ku Z, Xiong W, Deng H, Li Y, George J, McAllister DM, Sun Y, Kadamberi IP, Gupta P, Dwinell MB, Bradley WH, Rader JS, Rui H, Schwabe RF, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P.) Cancer Res. 2021 10 15;81(20):5336-5352 PMID: 34380633 PMCID: PMC8530981 SCOPUS ID: 2-s2.0-85116424540 08/13/2021

• NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers.

  (Sun Y, Yang N, Utama FE, Udhane SS, Zhang J, Peck AR, Yanac A, Duffey K, Langenheim JF, Udhane V, Xia G, Peterson JF, Jorns JM, Nevalainen MT, Rouet R, Schofield P, Christ D, Ormandy CJ, Rosenberg AL, Chervoneva I, Tsaih SW, Flister MJ, Fuchs SY, Wagner KU, Rui H.) Sci Adv. 2021 Sep 17;7(38):eabc8145 PMID: 34524841 PMCID: PMC8443188 SCOPUS ID: 2-s2.0-85115168052 09/16/2021

• Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies.

  (Puzyrenko A, Jacobs ER, Sun Y, Felix JC, Sheinin Y, Ge L, Lai S, Dai Q, Gantner BN, Nanchal R, North PE, Simpson PM, Rui H, Benjamin IJ.) Cell Stress Chaperones. 2021 09;26(5):859-868 PMID: 34382151 PMCID: PMC8357488 SCOPUS ID: 2-s2.0-85112285201 08/13/2021

• Diffuse interstitial pneumonia-like/macrophage activation syndrome-like changes in patients with COVID-19 correlate with length of illness.

  (Felix JC, Sheinin YM, Suster D, Ronen N, Ratiani M, Vanden Heuvel T, Winge E, Patton MD, Rau MJ, Ge L, Sun Y, Udhane SS, Langenheim JF, Rui H.) Ann Diagn Pathol. 2021 Aug;53:151744 PMID: 33991784 PMCID: PMC8053602 SCOPUS ID: 2-s2.0-85105597450 05/16/2021

• Sensitive and Specific Immunohistochemistry Protocol for Nucleocapsid Protein from All Common SARS-CoV-2 Virus Strains in Formalin-Fixed, Paraffin Embedded Tissues.

  (Sun Y, Ge L, Udhane SS, Langenheim JF, Rau MJ, Patton MD, Gallan AJ, Felix JC, Rui H.) Methods Protoc. 2021 Jul 10;4(3) PMID: 34287344 PMCID: PMC8293419 SCOPUS ID: 2-s2.0-85111011758 07/22/2021

• Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies.

  (Lu Z, Ortiz A, Verginadis II, Peck AR, Zahedi F, Cho C, Yu P, DeRita RM, Zhang H, Kubanoff R, Sun Y, Yaspan AT, Krespan E, Beiting DP, Radaelli E, Ryeom SW, Diehl JA, Rui H, Koumenis C, Fuchs SY.) J Clin Invest. 2021 05 17;131(10) PMID: 33998600 PMCID: PMC8121529 SCOPUS ID: 2-s2.0-85106569543 05/18/2021

• Acute SARS-CoV-2 pneumonitis with cytotoxic CD8 positive T-lymphocytes: Case report and review of the literature.

  (Puzyrenko A, Felix JC, Sun Y, Rui H, Sheinin Y.) Pathol Res Pract. 2021 Apr;220:153380 PMID: 33676105 PMCID: PMC7883708 SCOPUS ID: 2-s2.0-85101878778 03/07/2021

• Safety of apatinib plus S-1 for advanced solid tumor as palliative treatment.

  (Chen S, Sun J, Zhao L, Sun Y, Jia D, Song Y, Luo J, Lei H, Liu N.) Exp Ther Med. 2021 Jan;21(1):62 PMID: 33365062 PMCID: PMC7716638 12/29/2020

• The membrane-associated form of cyclin D1 enhances cellular invasion.

  (Chen K, Jiao X, Ashton A, Di Rocco A, Pestell TG, Sun Y, Zhao J, Casimiro MC, Li Z, Lisanti MP, McCue PA, Shen D, Achilefu S, Rui H, Pestell RG.) Oncogenesis. 2020 Sep 18;9(9):83 PMID: 32948740 PMCID: PMC7501870 SCOPUS ID: 2-s2.0-85091177817 09/20/2020