Years 2 and 3 of the Pediatric Hematology/Oncology/Blood and Marrow Transplant Program are dedicated to hypothesis-driven research. Two distinct research pathways are offered, laboratory-based research and clinical research. A major goal of our training program is to provide fellows a focused environment in which they can develop research interests and be positioned to successfully compete for extramural funding upon completion of their training. Each of our fellows is assigned a three-member Scholarship Oversight Committee (SOC) to help the fellow choose a suitable mentor and research project. The SOC will guide the fellow along with their research mentor meeting regularly during the 3 years of the fellowship training.
Multidisciplinary teams within the section take problems encountered in the clinic back to the laboratory to better understand cellular and molecular mechanisms, then return to the clinic with improved treatment strategies. Active translational research programs include experimental hematopoietic progenitor cell transplantation, cancer immunotherapy, mechanisms of vasoocclusion in sickle cell disease and bleeding disorders, and the diagnosis and treatment of vascular tumors and anomalies.
Fellows who choose to pursue the clinical research track are encouraged to also pursue a master's degree in Clinical and Translational Science, Public Health, or Bioethics (paid for by the Department of Pediatrics). The section of Hematology-Oncology has a long-standing commitment to basic and translational research that stems from the work carried out in our basic science laboratories, development of and participation in institutional and cooperative group trials (including Phase I trials), as well as in epidemiology and outcomes research. Important clinical questions are the focus of active collaborations involving clinical and basic science investigators within our section as well as expert research staff in neighboring research institutions.
The Blood Research Institute of the BloodCenter of Wisconsin and the Pediatric Hematology/Oncology/Blood and Marrow Transplant Division at the Medical College of Wisconsin have an ongoing collaboration that has contributed to an invaluable network of scientific discovery and patient care.
The Center for International Blood and Marrow Transplant Research (CIBMTR) is a combined research program of the National Marrow Donor Program and the Medical College of Wisconsin working to collect and study data on blood and bone marrow transplants worldwide. More than 500 international transplant centers collaborate with the CIBMTR to conduct research studies, collect, maintain, and share outcomes data on more than 300,000 transplant recipients, provide statistical expertise to researchers, and to provide education, guidelines, and training.
The Children's Research Institute advances state-of-the-art pediatric health care through translational research programs to find life-saving discoveries and cures in the disease that affect children and interventions that enhance quality of life for children and families living with chronic health conditions.
The Clinical Immunodiagnostic and Research Laboratory (CIRL) provides comprehensive diagnostic services and innovative methods to detect, diagnose, and treat immunologic, hematologic, and oncologic disease states.
The Medical College of Wisconsin Cancer Center is the only academic-based cancer research and patient care group in Southeastern Wisconsin. It is a matrix cancer center with clinical facilities at Froedtert Hospital, Children's Hospital of Wisconsin, and Zablocki VA Medical Center.
The MACC Fund, Midwest Athletes Against Childhood Cancer, Inc., a Milwaukee based charitable organization, works very closely with the Pediatric Hematology/Oncology/Blood and Marrow Transplant Division and the Medical College of Wisconsin to fight pediatric cancer and related blood disorders through research funding. Since its inception in 1976, the MACC Fund has contributed nearly $30 million to the College’s pediatric cancer and blood disorder research. This unique and exceptional affiliation provides researchers with the resources needed to fight against childhood cancer and related blood disorders.
With a wide variety of research options available, fellows have the opportunity to participate in an ongoing research project or establish projects of their own under a faculty mentor. Whether the fellow chooses a clinical research path or a basic science path, they will ultimately present their research at regional and national forums and publish in peer reviewed journals.