Pediatrics

Publications

• Persistent pulmonary hypertension alters the epigenetic characteristics of endothelial nitric oxide synthase gene in pulmonary artery endothelial cells in a fetal lamb model.

  (Ke X, Johnson H, Jing X, Michalkiewicz T, Huang YW, Lane RH, Konduri GG.) Physiol Genomics. 2018 Oct 01;50(10):828-836.

• DUSP5 functions as a feedback regulator of TNFα-induced ERK1/2 dephosphorylation and inflammatory gene expression in adipocytes.

  (Habibian JS, Jefic M, Bagchi RA, Lane RH, McKnight RA, McKinsey TA, Morrison RF, Ferguson BS.) Sci Rep. 2017 Oct 10;7(1):12879.

• Protective effect of maternal uteroplacental insufficiency on oxygen-induced retinopathy in offspring: removing bias of premature birth.

  (Becker S, Wang H, Yu B, Brown R, Han X, Lane RH, Hartnett ME.) Sci Rep. 2017 02 14;7:42301.

• Intrauterine growth restriction combined with a maternal high-fat diet increases hepatic cholesterol and low-density lipoprotein receptor activity in rats.

  (Zinkhan EK, Zalla JM, Carpenter JR, Yu B, Yu X, Chan G, Joss-Moore L, Lane RH.) Physiol Rep. 2016 Jul;4(13).

• Intrauterine growth restriction perturbs nucleosome depletion at a growth hormone-responsive element in the mouse IGF-1 gene.

  (McKnight RA, Yost CC, Yu X, Wiedmeier JE, Callaway CW, Brown AS, Lane RH, Fung CM.) Physiol Genomics. 2015 Dec;47(12):634-43.

• Programmed regulation of rat offspring adipogenic transcription factor (PPARγ) by maternal nutrition.

  (Desai M, Jellyman JK, Han G, Lane RH, Ross MG.) J Dev Orig Health Dis. 2015 Dec;6(6):530-8.

• The relationship between early-life environment, the epigenome and the microbiota.

  (Majnik AV, Lane RH.) Epigenomics. 2015 Oct;7(7):1173-84.

• Resistance strength training exercise in children with spinal muscular atrophy.

  (Lewelt A, Krosschell KJ, Stoddard GJ, Weng C, Xue M, Marcus RL, Gappmaier E, Viollet L, Johnson BA, White AT, Viazzo-Trussell D, Lopes P, Lane RH, Carey JC, Swoboda KJ.) Muscle Nerve. 2015 Oct;52(4):559-67.

• IUGR increases chromatin-remodeling factor Brg1 expression and binding to GR exon 1.7 promoter in newborn male rat hippocampus.

  (Ke X, McKnight RA, Gracey Maniar LE, Sun Y, Callaway CW, Majnik A, Lane RH, Cohen SS.) Am J Physiol Regul Integr Comp Physiol. 2015 Jul 15;309(2):R119-27.

• In utero nicotine exposure epigenetically alters fetal chromatin structure and differentially regulates transcription of the glucocorticoid receptor in a rat model.

  (Suter MA, Abramovici AR, Griffin E, Branch DW, Lane RH, Mastrobattista J, Rehan VK, Aagaard K.) Birth Defects Res A Clin Mol Teratol. 2015 Jul;103(7):583-8.

• IUGR prevents IGF-1 upregulation in juvenile male mice by perturbing postnatal IGF-1 chromatin remodeling.

  (Fung CM, Yang Y, Fu Q, Brown AS, Yu B, Callaway CW, Li J, Lane RH, McKnight RA.) Pediatr Res. 2015 Jul;78(1):14-23.

• Epigenetic contributions to the developmental origins of adult lung disease.

  (Joss-Moore LA, Lane RH, Albertine KH.) Biochem Cell Biol. 2015 Apr;93(2):119-27.