Alison Kriegel, PhD

Alison Kriegel, PhD

Associate Professor


  • Physiology

Contact Information


PhD, Physiology, Medical College of Wisconsin, 2008

Research Experience

  • Cardiovascular Physiological Phenomena
  • Cell Communication
  • Cell Physiological Phenomena
  • Hypertension
  • MicroRNA
  • Molecular Biology
  • Paracrine Communication
  • Physiological Genomics
  • Renal Physiology

Methodologies and Techniques

  • miRNA analysis
  • Models of Cardiac Pathology
  • Models of Renal Pathology
  • Next-generation RNA Sequencing
  • qRT-PCR
  • RNA analysis
  • Rodent Echocardiography
  • Rodent Left Ventricle Pressure-Volume Loop Analysis
  • Western Blot

Research Interests

Our research is broadly centered on understanding how alterations in microRNAs and protein coding genes influence pathology and organ function in cardiovascular disease, renal disease, and cardiorenal syndromes. Our laboratory takes an integrative physiology approach to research, recognizing the interconnectedness of molecular pathways and organ systems in physiology and pathophysiology.

Major areas of research:

  • Chronic Kidney Disease (CKD) and Metabolic Changes in CKD
  • Cardiorenal Syndrome, Hypertension, and Cardiovascular Disease
  • Polycystic Kidney Disease
  • Sex Differences in (Patho)Physiology
  • Cardio-Oncology

We combine in vivo approaches for studying cardiac and renal function with advanced molecular techniques to comprehensively study the factors that influence left ventricular pathology. Frequently utilized techniques in our laboratory include: echocardiography, left ventricle pressure-volume relationship analysis, chronic and acute blood pressure recordings, sodium handling/GFR assessment, cell culture models (siRNA, miRNA), in vitro and in vivo miRNA/mRNA suppression, immunohistochemistry, in situ hybridization, immuno/affinity purification, western blot analysis, ELISA, proteomic/metabolomic analysis, miRNA and mRNA next generation sequencing and qRT-PCR.

Please see the Kriegel lab website for additional information about our group and research.

Students and researchers interested in learning more about our dynamic research program are encouraged to contact Dr. Kriegel at