Edward Hackett completed his BS in animal biology-neurotoxicology with a minor in art history at the University of California at Davis in 2012. He stayed on at UC Davis earning his MS in pharmacology and toxicology in 2014. From there he worked at California Environmental Protection Agency (EPA) and then US EPA as a toxicologist before returning to research at the University of Southwestern Medical Center and now medical school at MCW.
Hackett’s research interests focuses on bridging molecular interactions with neurological and behavioural outcomes. Specifically, his project with Dr. Knight focuses on the interaction of cytotoxic release syndrome induced by chimeric antigen receptor (CAR) T cell cancer therapy with acute neurotoxicity, long-term changes in quality of life, and low socioeconomic status (SES) genomic profile. This multivariable study overview focuses on understanding the cyclic interaction between underlying inflammation that occurs due to CAR T-cell therapy and low SES with the acute and chronic neurologic and behavioural quality of life changes.