AOIP Young Investigator Series Seminar
Retinal Remodeling in the Pathoconnectome
Rebecca Pfeiffer, PhD Research Associate, University of Utah
Schedule includes 3-3:45 p.m. seminar with Q@A.
Rebecca attended the University of New Mexico for undergrad where she earned a BA in German and a BS with honors in Biology. She then attended the University of Utah for graduate school and joined the laboratory of Robert E. Marc. In Dr. Marc's lab she studied the long-term effects of photoreceptor degeneration on the inner retina with a special focus on Muller glial metabolism. After finishing her PhD, she joined the lab of Dr. Bryan Jones as a postdoc where she has been working to generate pathoconnectomes of progressive retinal degeneration in a rabbit model of retinitis pigmentosa. In October of 2020 she published the first of these retinal pathoconnectomes detailing the impact of early photoreceptor degeneration on the rod-pathway of the inner and outer retina. Rebecca's long-term goals are to use a combination of metabolomics and pathoconnectomics to better understand the interactions between neurons and glia during retinal degeneration. Ultimately, she hopes better understanding of the processes contributing to retinal remodeling will yield new therapeutic targets for intervention.