Metformin Treatment for Aging-Induced Immune Cell Decline

In this webinar, Dr. Leena Bharath will discuss the link between bioenergetics, aging, and inflammation. Inflammation rises in aging to limit healthspan, defined as the length of one’s life spent in good health. The decline in cellular homeostasis processes such as autophagy and the dysregulation of mitochondrial metabolism promotes the increased generation of proinflammatory cytokines during aging and fuels the development of diseases in the elderly. Therapeutics targeting inflammation and its underlying mechanisms will break this destructive cycle of events to impact multiple challenges to healthspan like diabetes, obesity and cardiovascular diseases.

Tune in to learn more about:

• T cells subsets and metabolism
• Aging-induced decline in autophagy and its mechanistic link to inflammation
• Mechanisms of Metformin action in correcting age-associated inflammation