Pharmacology and Toxicology

Welcome to the Department of Pharmacology and Toxicology at the Medical College of Wisconsin is dedicated to quality in research, graduate and postdoctoral training and medical education. The research interests of our faculty are broadly based in cardiovascular pharmacology, neuropharmacology, cancer pharmacology, toxicology and molecular pharmacology. The research programs in the Department of Pharmacology and Toxicology are also multidisciplinary in nature and have strong associations with researchers of other basic science and clinical departments. Read more about Pharmacology and Toxicology

John D. Imig, PhD

John D. Imig, PhD

Professor, Pharmacology and Toxicology

Can a research laboratory make major breakthroughs and develop novel therapeutics for cardiovascular and kidney diseases? The answer is a resounding, YES!

Dr. Imig’s research has focused on a class of fatty acids, arachidonic acid metabolites that have been targeted by drugs for the treatment of pain, fever, blood clotting, and asthma. Utilizing animal models of cardiovascular and kidney diseases his laboratory has demonstrated that arachidonic acid metabolites called epoxyeicosatrienoic acids (EETs) and the enzyme soluble epoxide hydrolase are not properly regulated during disease states. Over the past decade his laboratory was a major driving force in the development of drugs that inhibit the soluble epoxide hydrolase enzyme and one of these drugs is currently being tested in humans for the treatment of chronic obstructive pulmonary disease (COPD). More recently, the laboratory has focused on developing EET-based drugs for the treatment of hypertension, acute renal failure, and chronic kidney disease. These novel small molecule EET analogs are demonstrating great potential and could one day in the near future be used to treat cardiovascular and kidney diseases in humans.

Earn a graduate degree from Pharmacology and Toxicology

Graduate degree in Pharmacology and Toxicology

Our graduate degree program includes dynamically changing disciplines such as neuropharmacology and molecular pharmacology. This program receives many students from the Interdisciplinary Program of Neuroscience and Biomedical Science.

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Pharmacology & Toxicology Headlines

Pharmacology and Toxicology News

11/6/15: Graduate Student Yongik Lee wins award at 25th annual Graduate School Research Poster Session

9/25/15: CB2 transgenic mouse model developed by the Cecilia Hillard, PhD Lab.

7/9/15: Chris Olsen, PhD and Scott Levick, PhD named recipients of inaugural Presidential Faculty Scholar Awards.

Archived Pharmacology Headlines

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Other Pharmacology and Toxicology News

Medical College of Wisconsin names Dr. Carol Williams as Eminent Scholar

Apr. 27 - Carol L. Williams, PhD, was awarded Eminent Scholar designation at the March meeting of the Board of Trustees of the Medical College of Wisconsin (MCW). She joins Mingyu Liang, MB, PhD, who was named an Eminent Scholar in September 2015, and William Drobyski, MD, and Brian Link, PhD, who were named Eminent Scholars in March 2015.

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Calendar Events

Pharmacology & Toxicology Seminar "The Therapeutic Promise of Non-addicting Cannabinoid Analgesics" April 27

12:00 PM  - 1:00 PMDepartment of Pharmacology Conference Room, Basic Science Building, 6th Floor, Room 676

"The Therapeutic Promise of Non-addicting Cannabinoid Analgesics"

Contact Us

Pharmacology and Toxicology
Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226-0509

(414) 955-8267 | Fax: (414) 955-6545

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