Brockman Laboratory

Recent Publications

• High-depth RNA-Seq data sets to investigate the differences in gene expression mediated by phasevarions in non-typeable Haemophilus influenzae.

  (Atack JM, Brockman KL, Bakaletz LO, Jennings MP.) Microbiol Resour Announc. 2023 Dec 14;12(12):e0078523 PMID: 37991358 PMCID: PMC10720539 11/22/2023

• Phase variable acetylation of lipooligosaccharide modifies antibody production and opsonophagocytic killing of non-typeable Haemophilus influenzae.

  (Wills BM, Garai P, Dickinson Q, Meyer JG, Brockman KL.) iScience. 2023 Oct 20;26(10):107785 PMID: 37727736 PMCID: PMC10505976 09/20/2023

• Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection.

  (Wills BM, Garai P, Riegert MO, Sanchez FT, Pickrum AM, Frank DW, Brockman KL.) Infect Immun. 2023 Jul 18;91(7):e0003723 PMID: 37255468 PMCID: PMC10353400 SCOPUS ID: 2-s2.0-85165519693 05/31/2023

• Adherence of Nontypeable Haemophilus influenzae to Cells and Substrates of the Airway Is Differentially Regulated by Individual ModA Phasevarions.

  (Garai P, Atack JM, Wills BM, Jennings MP, Bakaletz LO, Brockman KL.) Microbiol Spectr. 2023 Feb 14;11(1):e0409322 PMID: 36511712 PMCID: PMC9927368 SCOPUS ID: 2-s2.0-85148113631 12/14/2022

• Phase variable acetylation of lipooligosaccharide modifies antibody production and opsonophagocytic killing of non-typeable Haemophilus influenzae

  (Wills BM, Garai P, Dickinson Q, Meyer JG, Brockman KL.) iScience. 20 October 2023;26(10) SCOPUS ID: 2-s2.0-85170435505 10/20/2023

• The In Vitro Replication Cycle of Achromobacter xylosoxidans and Identification of Virulence Genes Associated with Cytotoxicity in Macrophages.

  (Pickrum AM, Riegert MO, Wells C, Brockman K, Frank DW.) Microbiol Spectr. 2022 Aug 31;10(4):e0208322 PMID: 35856670 PMCID: PMC9430717 SCOPUS ID: 2-s2.0-85137137821 07/21/2022

• Characterization of the Phase-Variable Autotransporter Lav Reveals a Role in Host Cell Adherence and Biofilm Formation in Nontypeable Haemophilus influenzae.

  (Phillips ZN, Garai P, Tram G, Martin G, Van Den Bergh A, Husna AU, Staples M, Grimwood K, Jennison AV, Guillon P, von Itzstein M, Jennings MP, Brockman KL, Atack JM.) Infect Immun. 2022 Apr 21;90(4):e0056521 PMID: 35258316 PMCID: PMC9022572 SCOPUS ID: 2-s2.0-85128634430 03/09/2022

• The Nontypeable Haemophilus influenzae Major Adhesin Hia Is a Dual-Function Lectin That Binds to Human-Specific Respiratory Tract Sialic Acid Glycan Receptors.

  (Atack JM, Day CJ, Poole J, Brockman KL, Timms JRL, Winter LE, Haselhorst T, Bakaletz LO, Barenkamp SJ, Jennings MP.) mBio. 2020 Nov 03;11(6) PMID: 33144377 PMCID: PMC7642680 SCOPUS ID: 2-s2.0-85095613918 11/05/2020

• A Bacterial Epigenetic Switch in Non-typeable Haemophilus influenzae Modifies Host Immune Response During Otitis Media.

  (Robledo-Avila FH, Ruiz-Rosado JD, Partida-Sanchez S, Brockman KL.) Front Cell Infect Microbiol. 2020;10:512743 PMID: 33194779 PMCID: PMC7644868 SCOPUS ID: 2-s2.0-85095581955 11/17/2020

• A Bacterial Epigenetic Switch in Non-typeable Haemophilus influenzae Modifies Host Immune Response During Otitis Media

  (Robledo-Avila FH, Ruiz-Rosado JdD, Partida-Sanchez S, Brockman KL.) Frontiers in Cellular and Infection Microbiology. 23 October 2020;10 SCOPUS ID: 2-s2.0-85095581955 10/23/2020

• The TRPM2 Ion Channel Regulates Inflammatory Functions of Neutrophils During Listeria monocytogenes Infection.

  (Robledo-Avila FH, Ruiz-Rosado JD, Brockman KL, Partida-Sánchez S.) Front Immunol. 2020;11:97 PMID: 32117251 PMCID: PMC7010865 SCOPUS ID: 2-s2.0-85079677223 03/03/2020

• The TRPM2 Ion Channel Regulates Inflammatory Functions of Neutrophils During Listeria monocytogenes Infection

  (Robledo-Avila FH, Ruiz-Rosado JdD, Brockman KL, Partida-Sánchez S.) Frontiers in Immunology. 4 February 2020;11 SCOPUS ID: 2-s2.0-85079677223 02/04/2020