Biophysics 03230: Nuclear Magnetic Resonance (3 credits)
This course is designed as an introduction to nuclear magnetic resonance spectroscopy (MRS). Emphasis will be placed on modern MRS techniques and their application to structural determinations of biomolecules. Imaging-guided in vivo spectroscopy and its applications to biomedicine will also be introduced.
Biophysics 03239: Functional MRI Contrast Mechanisms and Applications (3 credits)
The use of MRI to evaluate tissue function will be described. The course will be dedicated to discussing fMRI methods that use both endogenous contrast (labeled water, deoxygenated blood) and exogenous (injectable) MR contrast agents to image tissue function. The theory and physiology necessary for understanding MR contrast mechanisms, together with the practical knowledge necessary for performing MR experiments, will be discussed. Demonstrations of fMRI experiments will be included.
Biophysics 03240: Fourier Transforms (3 credits)
This course provides basic knowledge for students who will continue to study EPR or NMR. Material will cover the theory of Fourier transforms, digital transforms, NMR images, reconstruction, pulse spectroscopy methods and electrical signal processing. An understanding of calculus and tensor vectors is recommended.
Biophysics 03238: Magnetic Resonance Imaging (3 credits)
This course focuses on the physics of modern MRI. It will take a classical approach to spin physics and will focus on pulse sequences, k-space analysis and hardware. An understanding of calculus is required.
Biophysics 03240: Fourier Transforms is required prior to taking this course.
Biophysics 03295: Readings and Research (1 to 9 credits)
Biophysics 03298: Biophysics MRI Journal Club (1 credit)
Selected papers in theory, practice and application of MRI will be read and discussed in separate sessions.
Biophysics 03300: Seminar (1 credit)
Weekly invited seminar speakers present their research on molecular biophysics or MRI topics.