Associate Professor Department of Pharmacology and Toxicology
The bad news is that cardiovascular disease is the number one cause of death of women in the US. The good news is that a focus of Dr. Pfister’s laboratory is to understand sex-based differences in vascular function. Using a rabbit model, her research identified a vasoconstrictor arachidonic acid metabolite (15-HETE) that is produced in greater amounts in females. The enzyme responsible for 15-HETE synthesis is induced by estrogen. Characterizing the mechanisms for estrogen modulation of 15-HETE production and function will likely provide new insights into female predominance in certain cardiovascular diseases and eventually lead to new options for treatments.
5/20/2013 . . . The Medical College of Wisconsin celebrates the 120th Anniversary of our founding. With nearly 200 significant research disoveries over the past 80 years, which included accolades to many pharmacology faculty members.
4/25/2013 . . . Scientists at the Medical College of Wisconsin and the University of California at Davis, Led by Dr. John Imig and Dr. Bruce Hammock have new treatment for Cardiometabolic Syndrome: Combined Epoxide Hydrolase Inhibition And Thiazolidinediones.
4/23/2013 . . . PhRMA Foundation Award in Excellence goes to, William B. Campbell, PhD, Professor and Chairman of Pharmacology and Toxicology.
3/13/2013 . . . William B. Campbell, PhD, Professor and Chairman of Pharmacology and Toxicology receives the 2013 Faculty Vitality Award.
3/5/2013 . . . CTSI Announces Pilot Award Recipients for 2013. Guan Chen, PhD and John Imig, PhD are part of the sixteen new research projects awarded this year.
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Our graduate degree program includes dynamically changing disciplines such as neuropharmacology and molecular pharmacology. This program receives many students from the Interdisciplinary Program of Neuroscience and Biomedical Science.