Structural Biology Shared Resource (SBSR)

The Structural Biology Shared Resource enables advanced atomic-level studies on the structure and function of cancer related molecules, macromolecules, and their interactions with drugs and biologicals.

Scheduling, Location, and Hours of Operation

Protein Purification Unit: Translational Biomedical Research Center (TBRC), 3rd floor
Cryo-EM facility: Health Research Center, Basement
X-ray Crystallography: Translational Biomedical Research building, 2nd floor
Monday–Friday from 8 a.m.-5 p.m.
Submit a SBSR iLab Request

Services and Technologies

The SBSR consists of the Protein Purification unit and the Structure Determination unit.

The Protein Purification unit produces homogeneous, high-quality proteins well-suited for downstream biophysical studies and structure determination.

The Structure Determination unit employs X-ray crystallography, Cryo-EM, and advanced AI-assisted analytical tools for structure determination and imaging.
Protein Production
  • I26R New Brunswick incubators
  • Aeolus compact CO2 incubators
  • Guava easyCyte cytometer
  • Optima XPN-80
  • NGC Bio-Rad
  • Akta Start
  • Shimatzu HPLC
  • Agilent 1260 Infinity
  • Thermo Ultimate 3000
  • Agilent Cary Eclipse
  • PELCO easiGlow
  • Thermo Fisher Glacios
  • Falcon 4 detector
  • Ceta-D Camera
  • Selectris
  • GPU workstations
X-ray Crystallography
  • Rigaku R-AXIS IV++
  • MicroMax 007
  • Oxford 800 Cryostream unit
  • Phoenix
  • Formulatrix Rock Imager



Wei Liu, PhD

Director, Structural Biology Shared Resource (SBSR)