Wei Liu, PhD

Publications

• Targeted degradation of GOLM1 by CC-885 via CRL4-CRBN E3 ligase inhibits hepatocellular carcinoma progression.

  (He J, Guo J, Liu S, Li H, Ma Y, Ma S, Hu Z, Zhao W, Tan M, Liu W, Liu B.) Cell Signal. 2025 Jun;130:111665 PMID: 39986359 SCOPUS ID: 2-s2.0-85218907304 02/23/2025

• Targeted degradation of CDK4/6 by LA-CB1 inhibits EMT and suppresses tumor growth in orthotopic breast cancer.

  (He J, Liu S, Zhang S, Gao Q, Zhu L, Xu N, Hu Z, Zhang X, Ma S, Wang X, Liu B, Liu W.) Sci Rep. 2025 Mar 04;15(1):7605 PMID: 40038413 PMCID: PMC11880390 SCOPUS ID: 2-s2.0-86000087831 03/05/2025

• Architecture and activation of single-pass transmembrane receptor guanylyl cyclase.

  (Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY.) Nat Struct Mol Biol. 2025 Mar;32(3):469-478 PMID: 39543315 SCOPUS ID: 2-s2.0-85208990896 11/15/2024

• A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.

  (Cheng W, Liu S, He J, Li H, Liu X, Hu Z, Wang X, Wu Z, Xu G, Liu W, Liu B.) Biochem Biophys Res Commun. 2025 Feb 16;749:151323 PMID: 39842333 SCOPUS ID: 2-s2.0-85215431954 01/23/2025

• Identification of MORF4L1 as an endogenous substrate of CRBN and its potential role as a therapeutic target in cancer.

  (Zhang L, Liu S, He J, Hu Z, Zhu L, Huang H, Gao Q, Wang D, Chen L, Zhang X, Liu R, Wang J, Song Y, Zeng K, Li X, Chen Y, Zou X, Ma S, Wang X, Xu G, Liu W, Liu B.) Sci Rep. 2025 Jan 18;15(1):2384 PMID: 39827217 PMCID: PMC11742918 SCOPUS ID: 2-s2.0-85216439171 01/20/2025

• Structural Insights into Dopamine Receptor-Ligand Interactions: From Agonists to Antagonists.

  (Barbosa ED, Ma Y, Clift HE, Olson LJ, Zhu L, Liu W.) ACS Chem Neurosci. 2024 Nov 20;15(22):4123-4131 PMID: 39485723 SCOPUS ID: 2-s2.0-85208389275 11/01/2024

• Portable Detection of Copper Ion Using Personal Glucose Meter.

  (Du B, Chen T, Huang A, Chen H, Liu W.) Sensors (Basel). 2024 Oct 31;24(21) PMID: 39517898 PMCID: PMC11548145 SCOPUS ID: 2-s2.0-85208578596 11/13/2024

• CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1.

  (Geng T, Sun Q, He J, Chen Y, Cheng W, Shen J, Liu B, Zhang M, Wang S, Asan K, Song M, Gao Q, Song Y, Liu R, Liu X, Ding Y, Jing A, Ye X, Ren H, Zeng K, Zhou Y, Zhang B, Ma S, Liu W, Liu S, Ji J.) Cell Signal. 2024 Jul;119:111180 PMID: 38642782 SCOPUS ID: 2-s2.0-85190884720 04/21/2024

• FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development.

  (Ji J, Qian Q, Cheng W, Ye X, Jing A, Ma S, Ding Y, Ma X, Wang Y, Sun Q, Wang X, Chen Y, Zhu L, Yuan Q, Xu M, Qin J, Ma L, Yang J, Zhang M, Geng T, Wang S, Wang D, Song Y, Zhang B, Xu Y, Xu L, Liu S, Liu W, Liu B.) Cell Death Dis. 2024 May 13;15(5):332 PMID: 38740744 PMCID: PMC11091054 SCOPUS ID: 2-s2.0-85192951272 05/14/2024

• FBXO5-mediated RNF183 degradation prevents endoplasmic reticulum stress-induced apoptosis and promotes colon cancer progression.

  (Ji J, Jing A, Ding Y, Ma X, Qian Q, Geng T, Cheng W, Zhang M, Sun Q, Ma S, Wang X, Yuan Q, Xu M, Qin J, Ma L, Yang J, He J, Du Q, Xia M, Xu Y, Chen Z, Zhu L, Liu W, Liu S, Liu B.) Cell Death Dis. 2024 Jan 11;15(1):33 PMID: 38212299 PMCID: PMC10784456 SCOPUS ID: 2-s2.0-85182091692 01/12/2024

• Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors.

  (Tan B, Liu C, Li K, Jadhav P, Lambrinidis G, Zhu L, Olson L, Tan H, Wen Y, Kolocouris A, Liu W, Wang J.) J Med Chem. 2023 Nov 09;66(21):14544-14563 PMID: 37857371 PMCID: PMC11457037 SCOPUS ID: 2-s2.0-85176509223 10/20/2023

• Editorial: Protein modifications in epigenetic dysfunctional diseases: mechanisms and potential therapeutic strategies.

  (Ji J, Jing A, Geng T, Ma X, Liu W, Liu B.) Front Cell Dev Biol. 2023;11:1216637 PMID: 37255602 PMCID: PMC10225621 SCOPUS ID: 2-s2.0-85161055462 05/31/2023