The MACC Fund Center for Cancer and Blood Disorders at Children's Hospital is among the most experienced and largest programs in the United States centering on a multidisciplinary approach to the care of patients with hematological, oncological, and immunological diseases. The Center is located near key resources and related disciplines to provide the most efficient, personalized and comprehensive care. These resources are enhanced by collaboration with partners such as the Medical College of Wisconsin and Blood Center of Wisconsin.
The pediatric blood and marrow transplant program is a joint venture between the Medical College of Wisconsin (MCW) and Children's Hospital of Wisconsin (CHW). The pediatric BMT Program is an integral part of the continuously FACT accredited MCW BMT Program which is a joint program integrating the transplant teams and services of Children’s Hospital of Wisconsin, Froedtert Hospital, The BloodCenter and MCW. The pediatric BMT program, initiated in 1980, has performed more than 900 transplants. The program is one of the largest and most experienced in the U.S. utilizing alternative donors such as unrelated individuals or mismatched family members as donors.
The Oncology Program at the Children’s Hospital of Wisconsin is among the most experienced and largest, specializing in the treatment of children with a wide variety of cancers. The Oncology Program focuses on offering new discoveries to our patients through clinical trial participation in consortium groups such as Children’s Oncology Group (COG), industry trials and investigator-initiated studies. The multidisciplinary oncology team includes highly trained specialists to diagnose and treat children's cancer and to help children and their families through the process. This is clinical expertise is paired with basic scientists with research foci including tumor immunology, cell signaling pathways in brain tumors and mitigation of therapy related injury by small molecules.
The Hematology Program offers comprehensive services for the treatment of children, adolescents and adults with acute and chronic blood diseases. The program includes general hematology services, the Wisconsin Sickle Cell Center and the Comprehensive Center for Bleeding Disorders, which are internationally known for their clinical care and research expertise. The program is a nationally recognized, federally funded center of excellence for bleeding and thrombotic disorders, and includes one of the country's leading basic research programs in hemophilia and von Willebrand disease. The Wisconsin Sickle Cell Center provides services comprehensive care for adults and children with SCD while striving to be at the forefront of basic, translational and outcomes related research in sickle cell disease. The center is one of only 11 sites nationwide awarded a National Institutes of Health Basic and Translational Research Program (BTRP). For our entire Hematology faculty, there is a close intertwining of research interests with clinical work to bring the lab to the bedside and the bedside to the lab.
Multidisciplinary teams within the section take problems encountered in the clinic back to the laboratory to better understand cellular and molecular mechanisms, then returning to the clinic with improved treatment strategies. Active translational research programs include experimental hematopoietic progenitor cell transplantation, cancer immunotherapy, mechanisms of vaso-occlusion in sickle cell disease and bleeding disorders, and the diagnosis and treatment of vascular tumors and anomalies.