Sunila Pradeep, PhD

Publications

• ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis.

  (Chen C, Gupta P, Parashar D, Nair GG, George J, Geethadevi A, Wang W, Tsaih SW, Bradley W, Ramchandran R, Rader JS, Chaluvally-Raghavan P, Pradeep S.) Oncogene. 2020 04;39(14):2921-2933 PMID: 32029900 PMCID: PMC7346970 SCOPUS ID: 2-s2.0-85079196544 02/08/2020

• Author Correction: Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression (Nature Communications, (2014), 5, 1, (5202), 10.1038/ncomms6202)

  (Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK.) Nature Communications. 1 December 2020;11(1) SCOPUS ID: 2-s2.0-85085855730 12/01/2020

• miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer.

  (Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P.) Cell Rep. 2019 12 24;29(13):4389-4406.e10 PMID: 31875548 PMCID: PMC7380555 SCOPUS ID: 2-s2.0-85076674271 12/26/2019

• B Cells as an Immune-Regulatory Signature in Ovarian Cancer.

  (Gupta P, Chen C, Chaluvally-Raghavan P, Pradeep S.) Cancers (Basel). 2019 Jun 26;11(7) PMID: 31248034 PMCID: PMC6678944 SCOPUS ID: 2-s2.0-85068665327 06/30/2019

• GnRH-R-Targeted Lytic Peptide Sensitizes BRCA Wild-type Ovarian Cancer to PARP Inhibition.

  (Ma S, Pradeep S, Villar-Prados A, Wen Y, Bayraktar E, Mangala LS, Kim MS, Wu SY, Hu W, Rodriguez-Aguayo C, Leuschner C, Liang X, Ram PT, Schlacher K, Coleman RL, Sood AK.) Mol Cancer Ther. 2019 05;18(5):969-979 PMID: 30926640 PMCID: PMC6497555 SCOPUS ID: 2-s2.0-85065508642 03/31/2019

• PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer.

  (Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK.) Mol Cancer Ther. 2019 01;18(1):162-172 PMID: 30305341 PMCID: PMC6318044 SCOPUS ID: 2-s2.0-85059497097 10/12/2018

• FABP4 as a key determinant of metastatic potential of ovarian cancer.

  (Gharpure KM, Pradeep S, Sans M, Rupaimoole R, Ivan C, Wu SY, Bayraktar E, Nagaraja AS, Mangala LS, Zhang X, Haemmerle M, Hu W, Rodriguez-Aguayo C, McGuire M, Mak CSL, Chen X, Tran MA, Villar-Prados A, Pena GA, Kondetimmanahalli R, Nini R, Koppula P, Ram P, Liu J, Lopez-Berestein G, Baggerly K, S Eberlin L, Sood AK.) Nat Commun. 2018 07 26;9(1):2923 PMID: 30050129 PMCID: PMC6062524 SCOPUS ID: 2-s2.0-85050737572 07/28/2018

• Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction.

  (Allen JK, Armaiz-Pena GN, Nagaraja AS, Sadaoui NC, Ortiz T, Dood R, Ozcan M, Herder DM, Haemmerle M, Gharpure KM, Rupaimoole R, Previs RA, Wu SY, Pradeep S, Xu X, Han HD, Zand B, Dalton HJ, Taylor M, Hu W, Bottsford-Miller J, Moreno-Smith M, Kang Y, Mangala LS, Rodriguez-Aguayo C, Sehgal V, Spaeth EL, Ram PT, Wong STC, Marini FC, Lopez-Berestein G, Cole SW, Lutgendorf SK, De Biasi M, Sood AK.) Cancer Res. 2018 06 15;78(12):3233-3242 PMID: 29661830 PMCID: PMC6004256 SCOPUS ID: 2-s2.0-85048711132 04/18/2018

• Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.

  (Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK.) JCI Insight. 2018 06 07;3(11) PMID: 29889661 PMCID: PMC6124393 SCOPUS ID: 2-s2.0-85062251133 06/12/2018

• Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens.

  (Nagaraja AS, Dood RL, Armaiz-Pena G, Kang Y, Wu SY, Allen JK, Jennings NB, Mangala LS, Pradeep S, Lyons Y, Haemmerle M, Gharpure KM, Sadaoui NC, Rodriguez-Aguayo C, Ivan C, Wang Y, Baggerly K, Ram P, Lopez-Berestein G, Liu J, Mok SC, Cohen L, Lutgendorf SK, Cole SW, Sood AK.) JCI Insight. 2018 Jun 07;3(11) PMID: 29889660 PMCID: PMC6124403 SCOPUS ID: 2-s2.0-85062250334 06/12/2018

• ADH1B promotes mesothelial clearance and ovarian cancer infiltration.

  (Gharpure KM, Lara OD, Wen Y, Pradeep S, LaFargue C, Ivan C, Rupaimoole R, Hu W, Mangala LS, Wu SY, Nagaraja AS, Baggerly K, Sood AK.) Oncotarget. 2018 May 18;9(38):25115-25126 PMID: 29861857 PMCID: PMC5982754 SCOPUS ID: 2-s2.0-85047209178 06/05/2018

• Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest.

  (Konson A, Pradeep S, D'Acunto CW, Seger R.) Cell Physiol Biochem. 2018;49(2):512-529 PMID: 30157491 SCOPUS ID: 2-s2.0-85052945008 08/30/2018