Sunila Pradeep, PhD

Publications

• Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens.

  (Nagaraja AS, Dood RL, Armaiz-Pena G, Kang Y, Wu SY, Allen JK, Jennings NB, Mangala LS, Pradeep S, Lyons Y, Haemmerle M, Gharpure KM, Sadaoui NC, Rodriguez-Aguayo C, Ivan C, Wang Y, Baggerly K, Ram P, Lopez-Berestein G, Liu J, Mok SC, Cohen L, Lutgendorf SK, Cole SW, Sood AK.) JCI Insight. 2021 04 08;6(7) PMID: 33793425 PMCID: PMC8119210 SCOPUS ID: 2-s2.0-85103808072 04/02/2021

• Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.

  (Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK.) JCI Insight. 2021 04 08;6(7) PMID: 33793423 PMCID: PMC8119196 SCOPUS ID: 2-s2.0-85103806720 04/02/2021

• Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling.

  (Parashar D, Nair B, Geethadevi A, George J, Nair A, Tsaih SW, Kadamberi IP, Gopinadhan Nair GK, Lu Y, Ramchandran R, Uyar DS, Rader JS, Ram PT, Mills GB, Pradeep S, Chaluvally-Raghavan P.) Cancer Res. 2020 12 15;80(24):5554-5568 PMID: 33087324 PMCID: PMC7744365 SCOPUS ID: 2-s2.0-85100331032 10/23/2020

• Emerging Role of Extracellular Vesicles in Immune Regulation and Cancer Progression.

  (Mittal S, Gupta P, Chaluvally-Raghavan P, Pradeep S.) Cancers (Basel). 2020 Nov 28;12(12) PMID: 33260606 PMCID: PMC7760253 SCOPUS ID: 2-s2.0-85096847824 12/03/2020

• NRG1/ERBB3 Pathway Activation Induces Acquired Resistance to XPO1 Inhibitors.

  (Miyake TM, Pradeep S, Bayraktar E, Stur E, Handley KF, Wu SY, Rodriguez-Aguayo C, Lee JS, Lopez-Berestein G, Coleman RL, Sood AK.) Mol Cancer Ther. 2020 08;19(8):1727-1735 PMID: 32499298 PMCID: PMC7415525 SCOPUS ID: 2-s2.0-85089165001 06/06/2020

• ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis.

  (Chen C, Gupta P, Parashar D, Nair GG, George J, Geethadevi A, Wang W, Tsaih SW, Bradley W, Ramchandran R, Rader JS, Chaluvally-Raghavan P, Pradeep S.) Oncogene. 2020 04;39(14):2921-2933 PMID: 32029900 PMCID: PMC7346970 SCOPUS ID: 2-s2.0-85079196544 02/08/2020

• Author Correction: Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression (Nature Communications, (2014), 5, 1, (5202), 10.1038/ncomms6202)

  (Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK.) Nature Communications. 1 December 2020;11(1) SCOPUS ID: 2-s2.0-85085855730 12/01/2020

• miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer.

  (Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P.) Cell Rep. 2019 12 24;29(13):4389-4406.e10 PMID: 31875548 PMCID: PMC7380555 SCOPUS ID: 2-s2.0-85076674271 12/26/2019

• B Cells as an Immune-Regulatory Signature in Ovarian Cancer.

  (Gupta P, Chen C, Chaluvally-Raghavan P, Pradeep S.) Cancers (Basel). 2019 Jun 26;11(7) PMID: 31248034 PMCID: PMC6678944 SCOPUS ID: 2-s2.0-85068665327 06/30/2019

• GnRH-R-Targeted Lytic Peptide Sensitizes BRCA Wild-type Ovarian Cancer to PARP Inhibition.

  (Ma S, Pradeep S, Villar-Prados A, Wen Y, Bayraktar E, Mangala LS, Kim MS, Wu SY, Hu W, Rodriguez-Aguayo C, Leuschner C, Liang X, Ram PT, Schlacher K, Coleman RL, Sood AK.) Mol Cancer Ther. 2019 05;18(5):969-979 PMID: 30926640 PMCID: PMC6497555 SCOPUS ID: 2-s2.0-85065508642 03/31/2019

• PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer.

  (Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK.) Mol Cancer Ther. 2019 01;18(1):162-172 PMID: 30305341 PMCID: PMC6318044 SCOPUS ID: 2-s2.0-85059497097 10/12/2018

• Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest.

  (Konson A, Pradeep S, D'Acunto CW, Seger R.) Cell Physiol Biochem. 2018;49(2):512-529 PMID: 30157491 SCOPUS ID: 2-s2.0-85052945008 08/30/2018