Jennifer M Connelly, MD | Medical College of Wisconsin

Jennifer M. Connelly, MD

Associate Professor

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Location

Cancer Center - Froedtert Hospital
8800 West Doyne Ave.
Milwaukee, WI 53226

Specialties

Neurology
Neuro-Oncology

Cancer Center - Froedtert Hospital

(414) 805-0505

Cancer Center - Froedtert Menomonee Falls Hospital

(262) 257-5100

My focus on every patient is not only on managing treatment of the tumor and prolonging life but also in maintaining quality of life with the tools we have available.

Overview

Diseases and Conditions

Brain Tumors
Metastases to the Nervous System
Neurofibromatosis (NF)
Neurologic Complications of Cancer and Cancer Therapies
Neurologic Paraneoplastic Syndromes
Neuromuscular Disease
Spine and Spinal Cord Tumors
Neurocutaneous Syndromes
Brain Metastasis

Treatments and Services

Virtual Visit

Patients Ages Seen

Adult
Senior

Languages

English

Hospital Affiliations

Froedtert Hospital – Milwaukee
Froedtert Menomonee Falls Hospital – Menomonee Falls

Board Certifications

Internal Medicine
Neurology
Neuro-Oncology

Clinic Locations

Cancer Center - Froedtert Hospital

8800 West Doyne Ave.
Milwaukee, WI 53226
(866) 680-0505
Get Directions

Cancer Center - Froedtert Menomonee Falls Hospital

W180 N8085 Town Hall Road
Menomonee Falls, WI 53051
(262) 251-1000
Get Directions

Biography

Dr. Jennifer Connelly’s expertise includes the diagnosis and treatment of a wide array of brain and spine tumors. More specifically, she is focused on tumors that begin or have spread (metastasized) to the brain or spine. In addition, her clinical interests include evaluating and treating neurologic complications of cancer and cancer therapies (including paraneoplastic syndromes seizures, and neuropathies). Her research interests include molecular pathology as well as development of advanced MRI imaging techniques for diagnosing and treating brain and spinal cord tumors. Her holistic patient-centered care focuses on improving quality of life outcomes for brain and spine tumor patients. A native of the Milwaukee area, Dr. Connelly has received all of her training at the Medical College of Wisconsin. Dr. Connelly is board certified in Internal Medicine, Neurology and Neuro-Oncology.

Education and Training

Doctor of Medicine - Medical College of Wisconsin - Milwaukee, WI (2003)
Fellowship in Neuro-Oncology - Medical College of Wisconsin Affiliated Hospitals - Milwaukee, WI (2008-2009)
Residency in Internal Medicine and Neurology - Medical College of Wisconsin Affiliated Hospitals - Milwaukee, WI (2003-2008)

Glioma progression is shaped by genetic evolution and microenvironment interactions.

(Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D'Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW, GLASS Consortium.) Cell. 2022 Jun 09;185(12):2184-2199.e16 PMID: 35649412 SCOPUS ID: 2-s2.0-85131903367 06/02/2022
Basal Ganglia Iron Content Increases with Glioma Severity Using Quantitative Susceptibility Mapping: A Potential Biomarker of Tumor Severity.

(Reith TP, Prah MA, Choi EJ, Lee J, Wujek R, Al-Gizawiy M, Chitambar CR, Connelly JM, Schmainda KM.) Tomography. 2022 03 15;8(2):789-797 PMID: 35314642 PMCID: PMC8938779 SCOPUS ID: 2-s2.0-85126905772 03/23/2022
Adrenocorticotropic Hormone Secreting Pituitary Carcinoma: Rare, Durable Response to Concurrent Chemotherapy and Reirradiation With a Review of the Literature

(Orr M, Findling J, Zwagerman N, Connelly J, Albano K, Bovi J.) Advances in Radiation Oncology. 1 March 2022;7(2) SCOPUS ID: 2-s2.0-85119325950 03/01/2022
Magnetic Resonance Imaging Mapping of Brain Tumor Burden: Clinical Implications for Neurosurgical Management: Case Report.

(Connelly JM, Prah MA, Santos-Pinheiro F, Mueller W, Cochran E, Schmainda KM.) Neurosurg Open. 2021 Dec;2(4):okab029 PMID: 34661110 PMCID: PMC8508085 10/19/2021
Sudden Paralysis in a 39-Year-Old Woman With Metastatic Breast Cancer.

(Griffiths C, Connelly J, Chaudhary LN.) JAMA Oncol. 2021 08 01;7(8):1239-1240 PMID: 34042938 SCOPUS ID: 2-s2.0-85107333574 05/28/2021
Quantitative analysis of Alzheimer's disease pathology in glioblastoma patients

(Brehler M, Lowman AK, Bobholz S, McGarry SD, Connelly J, Cochran E, Laviolette PS.) Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2021;11603 SCOPUS ID: 2-s2.0-85103234952 01/01/2021
Pulsed Reduced Dose Rate Radiotherapy in Conjunction With Bevacizumab or Bevacizumab Alone in Recurrent High-grade Glioma: Survival Outcomes.

(Bovi JA, Prah MA, Retzlaff AA, Schmainda KM, Connelly JM, Rand SD, Marszalkowski CS, Mueller WM, Siker ML, Schultz CJ.) Int J Radiat Oncol Biol Phys. 2020 11 15;108(4):979-986 PMID: 32599030 PMCID: PMC8655709 SCOPUS ID: 2-s2.0-85089292279 07/01/2020
NRG/RTOG 1122: A phase 2, double-blinded, placebo-controlled study of bevacizumab with and without trebananib in patients with recurrent glioblastoma or gliosarcoma.

(Lee EQ, Zhang P, Wen PY, Gerstner ER, Reardon DA, Aldape KD, deGroot JF, Pan E, Raizer JJ, Kim LJ, Chmura SJ, Robins HI, Connelly JM, Battiste JD, Villano JL, Wagle N, Merrell RT, Wendland MM, Mehta MP.) Cancer. 2020 06 15;126(12):2821-2828 PMID: 32154928 PMCID: PMC7245544 SCOPUS ID: 2-s2.0-85081276146 03/11/2020
Radiomic Features of Multiparametric MRI Present Stable Associations With Analogous Histological Features in Patients With Brain Cancer.

(Bobholz SA, Lowman AK, Barrington A, Brehler M, McGarry S, Cochran EJ, Connelly J, Mueller WM, Agarwal M, O'Neill D, Nencka AS, Banerjee A, LaViolette PS.) Tomography. 2020 06;6(2):160-169 PMID: 32548292 PMCID: PMC7289245 SCOPUS ID: 2-s2.0-85086686895 06/18/2020
Longitudinal molecular trajectories of diffuse glioma in adults.

(Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW, GLASS Consortium.) Nature. 2019 12;576(7785):112-120 PMID: 31748746 PMCID: PMC6897368 SCOPUS ID: 2-s2.0-85075234677 11/22/2019
High-dose intravenous methotrexate in the management of breast cancer with leptomeningeal disease: Case series and review of the literature.

(Kapke JT, Schneidewend RJ, Jawa ZA, Huang CC, Connelly JM, Chitambar CR.) Hematol Oncol Stem Cell Ther. 2019 Dec;12(4):189-193 PMID: 31629723 SCOPUS ID: 2-s2.0-85075443191 10/21/2019
Moving Toward a Consensus DSC-MRI Protocol: Validation of a Low-Flip Angle Single-Dose Option as a Reference Standard for Brain Tumors.

(Schmainda KM, Prah MA, Hu LS, Quarles CC, Semmineh N, Rand SD, Connelly JM, Anderies B, Zhou Y, Liu Y, Logan B, Stokes A, Baird G, Boxerman JL.) AJNR Am J Neuroradiol. 2019 04;40(4):626-633 PMID: 30923088 PMCID: PMC6461489 SCOPUS ID: 2-s2.0-85064588009 03/30/2019