Jennifer M. Connelly, MD

Publications

• Glioma progression is shaped by genetic evolution and microenvironment interactions.

  (Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D'Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW, GLASS Consortium.) Cell. 2022 Jun 09;185(12):2184-2199.e16 PMID: 35649412 PMCID: PMC9189056 SCOPUS ID: 2-s2.0-85131903367 06/02/2022

• Radio-Pathomic Maps of Cell Density Identify Brain Tumor Invasion beyond Traditional MRI-Defined Margins.

  (Bobholz SA, Lowman AK, Brehler M, Kyereme F, Duenweg SR, Sherman J, McGarry SD, Cochran EJ, Connelly J, Mueller WM, Agarwal M, Banerjee A, LaViolette PS.) AJNR Am J Neuroradiol. 2022 May;43(5):682-688 PMID: 35422419 PMCID: PMC9089258 SCOPUS ID: 2-s2.0-85130001814 04/16/2022

• Basal Ganglia Iron Content Increases with Glioma Severity Using Quantitative Susceptibility Mapping: A Potential Biomarker of Tumor Severity.

  (Reith TP, Prah MA, Choi EJ, Lee J, Wujek R, Al-Gizawiy M, Chitambar CR, Connelly JM, Schmainda KM.) Tomography. 2022 Mar 15;8(2):789-797 PMID: 35314642 PMCID: PMC8938779 SCOPUS ID: 2-s2.0-85126905772 03/23/2022

• Case report: Fractional brain tumor burden magnetic resonance mapping to assess response to pulsed low-dose-rate radiotherapy in newly-diagnosed glioblastoma.

  (Amidon RF, Santos-Pinheiro F, Straza M, Prah MA, Mueller WM, Krucoff MO, Connelly JM, Kleefisch CJ, Coss DJ, Cochran EJ, Bovi JA, Schultz CJ, Schmainda KM.) Front Oncol. 2022;12:1066191 PMID: 36561526 PMCID: PMC9763264 SCOPUS ID: 2-s2.0-85144231369 12/24/2022

• Adrenocorticotropic Hormone Secreting Pituitary Carcinoma: Rare, Durable Response to Concurrent Chemotherapy and Reirradiation With a Review of the Literature

  (Orr M, Findling J, Zwagerman N, Connelly J, Albano K, Bovi J.) Advances in Radiation Oncology. 1 March 2022;7(2) SCOPUS ID: 2-s2.0-85119325950 03/01/2022

• Magnetic Resonance Imaging Mapping of Brain Tumor Burden: Clinical Implications for Neurosurgical Management: Case Report.

  (Connelly JM, Prah MA, Santos-Pinheiro F, Mueller W, Cochran E, Schmainda KM.) Neurosurg Open. 2021 Dec;2(4):okab029 PMID: 34661110 PMCID: PMC8508085 10/19/2021

• Sudden Paralysis in a 39-Year-Old Woman With Metastatic Breast Cancer.

  (Griffiths C, Connelly J, Chaudhary LN.) JAMA Oncol. 2021 Aug 01;7(8):1239-1240 PMID: 34042938 SCOPUS ID: 2-s2.0-85107333574 05/28/2021

• Quantitative analysis of Alzheimer's disease pathology in glioblastoma patients

  (Brehler M, Lowman AK, Bobholz S, McGarry SD, Connelly J, Cochran E, Laviolette PS.) Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2021;11603 SCOPUS ID: 2-s2.0-85103234952 01/01/2021

• Pulsed Reduced Dose Rate Radiotherapy in Conjunction With Bevacizumab or Bevacizumab Alone in Recurrent High-grade Glioma: Survival Outcomes.

  (Bovi JA, Prah MA, Retzlaff AA, Schmainda KM, Connelly JM, Rand SD, Marszalkowski CS, Mueller WM, Siker ML, Schultz CJ.) Int J Radiat Oncol Biol Phys. 2020 Nov 15;108(4):979-986 PMID: 32599030 PMCID: PMC8655709 SCOPUS ID: 2-s2.0-85089292279 07/01/2020

• NRG/RTOG 1122: A phase 2, double-blinded, placebo-controlled study of bevacizumab with and without trebananib in patients with recurrent glioblastoma or gliosarcoma.

  (Lee EQ, Zhang P, Wen PY, Gerstner ER, Reardon DA, Aldape KD, deGroot JF, Pan E, Raizer JJ, Kim LJ, Chmura SJ, Robins HI, Connelly JM, Battiste JD, Villano JL, Wagle N, Merrell RT, Wendland MM, Mehta MP.) Cancer. 2020 Jun 15;126(12):2821-2828 PMID: 32154928 PMCID: PMC7245544 SCOPUS ID: 2-s2.0-85081276146 03/11/2020

• Radiomic Features of Multiparametric MRI Present Stable Associations With Analogous Histological Features in Patients With Brain Cancer.

  (Bobholz SA, Lowman AK, Barrington A, Brehler M, McGarry S, Cochran EJ, Connelly J, Mueller WM, Agarwal M, O'Neill D, Nencka AS, Banerjee A, LaViolette PS.) Tomography. 2020 Jun;6(2):160-169 PMID: 32548292 PMCID: PMC7289245 SCOPUS ID: 2-s2.0-85086686895 06/18/2020

• Longitudinal molecular trajectories of diffuse glioma in adults.

  (Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW, GLASS Consortium.) Nature. 2019 Dec;576(7785):112-120 PMID: 31748746 PMCID: PMC6897368 SCOPUS ID: 2-s2.0-85075234677 11/22/2019