
Zachary Smith, DO
Assistant Professor; Associate Chief, Director of Clinical Research
Location
- Gastroenterology and Hepatology - Froedtert Hospital
- 900 N. 92nd St.
- Milwaukee, WI 53226
Specialties
- Gastroenterology
New & Established Patients Call
I pride myself on establishing a meaningful relationship with all patients I care for. As an interventional endoscopist, I often see patients that are referred from other gastroenterologists and physicians for complex endoscopic problems. This occasionally results in meeting the patient for the first time right before his/her procedure. I make every effort to explain the problem, and the treatment plan to the patient and his/her loved one(s) so that they understand what we propose to do and what the next steps will be. Additionally, I place a high value on multidisciplinary care and collaboration. Many patients I treat are also cared for by other specialists and in these circumstances, input from the entire treatment team is imperative to optimize patient outcomes. Further, some conditions such as pancreatic fluid collections have various treatment options that span disciplines such as hepato-pancreaticobiliary surgery and interventional radiology. Only when we discuss and plan treatment strategies in a collaborative manner, are we able to achieve the best outcomes for our patients.
Overview
Diseases and Conditions
- Barrett's Esophagus
- Bile Duct Cancer
- Esophageal Cancer
- Pancreatic Cancer
- Pancreatitis
- Pancreatobiliary Disease
- Polyps
- Bile Duct Disorders
- Pancreatic Fluid Collections
Treatments and Services
- Stenting of the GI Tract
- ERCP
- Endoscopic Ultrasound (EUS)
- Endoscopic Mucosal Resection (EMR)
- Interventional Endoscopy
- Endoscopic Suturing
- Endotherapy for Barrett's Esophagus
- Endoscopic Management of Perforations, Leaks and Fistulas
Patients Ages Seen
- Adult
- Senior
Languages
- English
Hospital Affiliations
- Froedtert Hospital – Milwaukee
- Zablocki VA Medical Center – Milwaukee
Board Certifications
- Gastroenterology
- Internal Medicine
Clinic Locations
Gastroenterology and Hepatology - Froedtert Hospital
- 900 N. 92nd St.
- Milwaukee, WI 53226
- (414) 805-3310
- Get Directions

Biography
Dr. Smith did his Gastroenterology and Hepatology training at the Medical College of Wisconsin. After pursuing subspecialty training in interventional endoscopy at Washington University School of Medicine in St. Louis, and spending three years on faculty at Case Western Reserve University School of Medicine in Cleveland, he returned to MCW in 2020 to join the faculty in the Division of Gastroenterology and Hepatology. His clinical expertise is interventional endoscopy and pancreaticobiliary disorders. Dr. Smith has extensive research interests in many fields of gastrointestinal endoscopy and his primary research focus at MCW is to design and conduct clinical trials and other high-impact studies that will help shape best practices of gastrointestinal endoscopy in the future.
Education and Training
Doctor of Osteopathic Medicine - Michigan State University College of Osteopathic Medicine - East Lansing, MI (2009)
Residency in Internal Medicine - University of Chicago Pritzker School of Medicine/NorthShore University HealthSystem - Evanston, IL (2009-2012)
Chief Resident - Internal Medicine - University of Chicago Pritzker School of Medicine/NorthShore University HealthSystem - Evanston, IL (2012-2013)
Fellowship in Gastroenterology and Hepatology - Medical College of Wisconsin Affiliated Hospitals - Milwaukee, WI (2013-2016)
Fellowship in Interventional Endoscopy - Washington University School of Medicine - St. Louis, MO (2016-2017)
Publications
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(Satyavada S, Smith ZL.) Am J Gastroenterol. 2022 May 01;117(5):811 PMID: 35315811 03/23/2022
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Meet EBE: The Development of an Evidence-Based Endoscopy Simulator.
(Shah R, Satyavada S, Kurin M, Ismail M, Smith ZL, Davitkov P, Isenberg G, Raju GS, Faulx A, Falck-Ytter Y, Chak A.) Clin Gastroenterol Hepatol. 2022 May;20(5):e1180-e1187 PMID: 34896643 SCOPUS ID: 2-s2.0-85123711660 12/14/2021
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(Cummings LC, Liang C, Mascha EJ, Saager L, Smith ZL, Bhavani S, Vargo JJ, Cummings KC 3rd.) Gastrointest Endosc. 2022 Apr 02 PMID: 35381231 04/06/2022
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(Mehta D, Loutfy AH, Kushnir VM, Faulx AL, Smith ZL.) Endoscopy. 2022 04;54(4):367-375 PMID: 33782926 SCOPUS ID: 2-s2.0-85107296278 03/31/2021
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(Smith ZL, Satyavada S, Simons-Linares R, Mok SRS, Martinez Moreno B, Aparicio JR, Chahal P.) Am J Gastroenterol. 2022 03 01;117(3):478-485 PMID: 35034045 SCOPUS ID: 2-s2.0-85125682555 01/17/2022
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(Aroniadis OC, Wang X, Gong T, Forbes N, Yang JY, Canakis A, Elmunzer BJ, Yadav D, North American Alliance for the Study of Digestive Manifestations of Covid-19.) Dig Dis Sci. 2021 Nov 09 PMID: 34751837 PMCID: PMC8575674 SCOPUS ID: 2-s2.0-85118765038 11/10/2021
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(Nakai Y, Smith Z, Chang KJ, Dua KS.) Surg Oncol Clin N Am. 2021 10;30(4):639-656 PMID: 34511187 SCOPUS ID: 2-s2.0-85111001118 09/14/2021
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Behind the mask: physiologic effects of facial personal protective equipment during endoscopy.
(Chisholm PR, Smith ZL.) Gastrointest Endosc. 2021 07;94(1):169-171 PMID: 33975713 PMCID: PMC8106483 SCOPUS ID: 2-s2.0-85105456884 05/13/2021
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(Forbes N, Chau M, Koury HF, Lethebe BC, Smith ZL, Wani S, Keswani RN, Elmunzer BJ, Anderson JT, Heitman SJ, Hilsden RJ.) Gastrointest Endosc. 2021 07;94(1):103-110.e2 PMID: 33385464 PMCID: PMC8761529 SCOPUS ID: 2-s2.0-85103731041 01/02/2021
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The role of endoscopy and findings in COVID-19 patients, an early North American Cohort.
(Kuftinec G, Elmunzer BJ, Amin S, North American Alliance for the Study of Digestive Manifestations of Covid-19.) BMC Gastroenterol. 2021 May 07;21(1):205 PMID: 33962582 PMCID: PMC8102844 SCOPUS ID: 2-s2.0-85105708182 05/09/2021
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(Nakai Y, Smith Z, Chang KJ, Dua KS.) Surgical Oncology Clinics of North America. October 2021;30(4):639-656 SCOPUS ID: 2-s2.0-85111001118 10/01/2021
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Behind the mask: physiologic effects of facial personal protective equipment during endoscopy
(Chisholm PR, Smith ZL.) Gastrointestinal Endoscopy. July 2021;94(1):169-171 SCOPUS ID: 2-s2.0-85105456884 07/01/2021