Peter S. LaViolette, PhD, MS
Robert C. Olson, MD, Professorship in Radiology; Director, Quantitative Imaging Laboratory, Medical College of Wisconsin; Section of Imaging Research, Division of Imaging Sciences
Locations
- Medical College of Wisconsin
Department of Radiology
Contact Information
Education
PhD, Biophysics, Medical College of Wisconsin, Milwaukee, WI, 2011
MA, MS, Physics, University of Massachusetts, Amherst, MA, 2005
BS, Physics, St. Norbert College, De Pere, WI, 2003
Research Interests
The overall goal of my lab’s research is creating and validating imaging techniques that improve both patient outcome and treatment efficacy. I primarily work with neurological diseases such as brain cancer and epilepsy in a translational setting, collaborating with clinicians for the betterment of patient care.
Our brain cancer research has been focused on characterizing brain tumor cellularity and vascularity through imaging methods such as diffusion and perfusion MRI. The neuro-imaging techniques we develop are used to determine whether brain tumors respond to therapy or signal when brain tumors are progressing. In addition to patient outcome studies, we study the histological features responsible for the imaging characteristics measures in-vivo. This provides us with a validation technique for assessing our imaging biomarkers.
My epilepsy research is mainly focused on development of image processing techniques meant to help clinicians better plan surgery and map out brain function.
Publications
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(Nocera G, Sanvito F, Yao J, Oshima S, Bobholz SA, Teraishi A, Raymond C, Patel K, Everson RG, Liau LM, Connelly J, Castellano A, Mortini P, Salamon N, Cloughesy TF, LaViolette PS, Ellingson BM.) J Neurooncol. 2025 Oct;175(1):111-122 PMID: 40542949 PMCID: PMC12367939 SCOPUS ID: 2-s2.0-105008481709 06/21/2025
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(Mulkearns-Hubert EE, Hajdari N, Hong ES, Jacobs AP, Gaboriau A, Giltner S, Tannish G, Kay KE, Wang SZ, LaViolette PS, Silver DJ, Hubert CG, Dhawan A, Lathia JD.) Cell Rep. 2025 Sep 23;44(9):116303 PMID: 40946315 PMCID: PMC12443334 09/14/2025
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(Bobholz SA, Aaronsen D, Winiarz A, Duenweg SR, Lowman AK, Flatley M, Kyereme F, Connelly J, Mrachek EKS, Krucoff MO, Banerjee A, LaViolette PS.) Neuro Oncol. 2025 Sep 08;27(7):1899-1909 PMID: 39960860 PMCID: PMC12417833 SCOPUS ID: 2-s2.0-105015499764 02/17/2025
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(Das D, Iyer M, Nakamura B, Sedighi S, Hsu A, Danilov C, LaViolette PS, Connelly J, Chow F, Neman J.) Neuro Oncol. 2025 Jul 30;27(6):1476-1490 PMID: 39883056 PMCID: PMC12309716 SCOPUS ID: 2-s2.0-105012240300 01/30/2025
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Tumor-initiating genetics and therapy drive divergent molecular evolution in IDH-mutant gliomas.
(Chowdhury T, Tesileanu CMS, Kocakavuk E, Johnson KC, Lee J, Erson-Omay Z, Heo C, Aldape K, Amin SB, Anderson KJ, Ashley DM, Barnholtz-Sloan JS, Brat DJ, Brodbelt AR, Castro AV, Claus EB, Connelly JM, Costello J, Datta I, Elliott C, Finocchiaro G, French PJ, Gan HK, Garofano L, Ghospurkar PL, Golebiewska A, Gundla PS, Hermes B, Hong C, Hoogstrate Y, Horbinski C, Huse JT, Iavarone A, Karadag C, Khasraw M, Kouwenhoven MC, LaViolette PS, Li K, Lowman A, McCortney K, Moon HE, Nader S, Nasrallah MP, Ng HK, Ormond DR, Padovan M, Paek SH, Poisson LM, Puri S, Shen E, Shwetal M, Sloan AE, Vallentgoed WR, Van Meir EG, Vaubel R, Wade T, Walenkamp AM, Watts C, Weiss T, Weller M, Wesseling P, Westcott K, Westerman B, Ye GY, Yung WKA, GLASS Consortium, Varn FS, Verhaak RG.) bioRxiv. 2025 Jul 15 PMID: 40791422 PMCID: PMC12338597 08/12/2025
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(Sridhar S, Abouelfetouh Z, Codreanu I, Gupta N, Zhang S, Efstathiou E, Karolyi DK, Shen SS, LaViolette PS, Miles B, Martin DR.) Prostate. 2025 Apr;85(5):413-423 PMID: 39702937 PMCID: PMC11848987 12/20/2024
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(Maranto C, Udhane V, Jia J, Verma R, Müller-Newen G, LaViolette PS, Pereckas M, Sabharwal L, Terhune S, Pattabiraman N, Njar VCO, Imig JD, Wang L, Nevalainen MT.) Cancers (Basel). 2025 Mar 10;17(6) PMID: 40149386 PMCID: PMC11940198 03/28/2025
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Radio-pathomic estimates of cellular growth kinetics predict survival in recurrent glioblastoma.
(Oshima S, Yao J, Bobholz S, Nagaraj R, Raymond C, Teraishi A, Guenther AM, Kim A, Sanvito F, Cho NS, Eldred BSC, Connelly JM, Nghiemphu PL, Lai A, Salamon N, Cloughesy TF, LaViolette PS, Ellingson BM.) CNS Oncol. 2024 Dec 31;13(1):2415285 PMID: 39535237 PMCID: PMC11562955 SCOPUS ID: 2-s2.0-85209813692 11/13/2024
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(Bobholz SA, Lowman AK, Connelly JM, Duenweg SR, Winiarz A, Nath B, Kyereme F, Brehler M, Bukowy J, Coss D, Lupo JM, Phillips JJ, Ellingson BM, Krucoff MO, Mueller WM, Banerjee A, LaViolette PS.) Neurosurgery. 2024 Sep 01;95(3):537-547 PMID: 38501824 PMCID: PMC11302944 SCOPUS ID: 2-s2.0-85201436914 03/19/2024
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(Bobholz SA, Hoefs A, Hamburger J, Lowman AK, Winiarz A, Duenweg SR, Kyereme F, Connelly J, Coss D, Krucoff M, Banerjee A, LaViolette PS.) J Neurooncol. 2024 Apr;167(2):243 PMID: 38498261 PMCID: PMC11023959 SCOPUS ID: 2-s2.0-85187929260 03/19/2024
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Morphologic features of prostate cancer-encased native vessels: An image analysis study.
(Fernandez Gonzalez De La Vega C, Duenweg S, Jain P, Rubenstein SI, Bobholz S, Barrett MJ, LaViolette PS, Iczkowski KA.) Pathol Res Pract. 2024 Apr;256:155239 PMID: 38461692 03/11/2024
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(Bobholz SA, Hoefs A, Hamburger J, Lowman AK, Winiarz A, Duenweg SR, Kyereme F, Connelly J, Coss D, Krucoff M, Banerjee A, LaViolette PS.) J Neurooncol. 2024 Apr;167(2):233-241 PMID: 38372901 PMCID: PMC11024025 SCOPUS ID: 2-s2.0-85185314152 02/19/2024