Herve Falet, PhD

Publications

• Dynamin 2 is required for GPVI signaling and platelet hemostatic function in mice.

  (Eaton N, Drew C, Wieser J, Munday AD, Falet H.) Haematologica. 2019 Jul 11.

• Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets.

  (Sladojevic N, Oh GT, Kim HH, Beaulieu LM, Falet H, Kaminski K, Freedman JE, Liao JK.) Cardiovasc Res. 2017 Sep 01;113(11):1307-1317.

• Singling out FLI1 in Paris-Trousseau syndrome.

  (Falet H.) Blood. 2017 06 29;129(26):3399-3401.

• Glycans and the platelet life cycle.

  (Li R, Hoffmeister KM, Falet H.) Platelets. 2016 Sep;27(6):505-11.

• Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases.

  (Crescente M, Pluthero FG, Li L, Lo RW, Walsh TG, Schenk MP, Holbrook LM, Louriero S, Ali MS, Vaiyapuri S, Falet H, Jones IM, Poole AW, Kahr WH, Gibbins JM.) Arterioscler Thromb Vasc Biol. 2016 06;36(6):1164-73.

• Platelet clearance by the hepatic Ashwell-Morrell receptor: mechanisms and biological significance.

  (Hoffmeister KM, Falet H.) Thromb Res. 2016 May;141 Suppl 2:S68-72.

• Regulating billions of blood platelets: glycans and beyond.

  (Grozovsky R, Giannini S, Falet H, Hoffmeister KM.) Blood. 2015 Oct 15;126(16):1877-84.

• Novel mechanisms of platelet clearance and thrombopoietin regulation.

  (Grozovsky R, Giannini S, Falet H, Hoffmeister KM.) Curr Opin Hematol. 2015 Sep;22(5):445-51.

• FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.

  (Begonja AJ, Pluthero FG, Suphamungmee W, Giannini S, Christensen H, Leung R, Lo RW, Nakamura F, Lehman W, Plomann M, Hoffmeister KM, Kahr WH, Hartwig JH, Falet H.) Blood. 2015 Jul 02;126(1):80-8.

• Corrigendum: Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect.

  (Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B.) Nat Commun. 2015 Mar 06;6:6507.

• Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice.

  (Bender M, Giannini S, Grozovsky R, Jönsson T, Christensen H, Pluthero FG, Ko A, Mullally A, Kahr WH, Hoffmeister KM, Falet H.) Blood. 2015 Feb 05;125(6):1014-24.

• The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling.

  (Grozovsky R, Begonja AJ, Liu K, Visner G, Hartwig JH, Falet H, Hoffmeister KM.) Nat Med. 2015 Jan;21(1):47-54.