Matthew D. Budde, PhD

Associate Professor

Locations

Neurosurgery
8701 Watertown Plank Rd.
Milwaukee, WI 53226

Education

BS, Psychology, University of Wisconsin, Madison, WI, 2001
PhD, Neuroscience, Washington University, St Louis, MO, 2008
Postdoctoral Fellow, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 2011

Biography

Dr. Matthew Budde is an Associate Professor of Neurosurgery at the Medical College of Wisconsin. He received his PhD in Neuroscience from Washington University in St. Louis in 2008. He completed his postdoctoral training at the National Institutes of Health in Bethesda, MD and was a recipient of the Fellows Award for Research Excellence in 2011.

Dr. Budde’s primary research interest is to develop and employ magnetic resonance imaging techniques to diagnosis and monitor injuries and diseases of the central nervous system. He has made significant contributions to the field and has over 20 peer-reviewed publications. He is an active member and Junior Fellow of the International Society for Magnetic Resonance in Medicine and a member of the Society for Neuroscience.

Honors and Awards

05/2006 – Young Investigator Award Finalist, International Society for Magnetic Resonance in Medicine
05/2010 – Junior Fellow Recipient, International Society for Magnetic Resonance in Medicine
02/2011 – Fellows Award for Research Excellence (FARE), National Institutes of Health, Bethesda, National Institutes of Health

Research Experience

Brain Concussion
Brain Injuries
Diffuse Axonal Injury
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging
Disease Models, Animal
Histology
Hypoxia-Ischemia, Brain
Magnetic Resonance Imaging
Microscopy
Multiple Sclerosis
Neurosciences

MCW Program / Core Facilities

Center for Imaging Research
Neuroscience Research Center

Research Interests

Development and application of magnetic resonance imaging techniques to diagnose and monitor brain and spinal cord injury.

Apply advanced MRI techniques, including diffusion tensor imaging (DTI), to detect and monitor injury to the central nervous system noninvasively
Define the specific biological features that give rise to the MRI findings using animal models of neurological injury
Determine the prognostic capabilities of MRI in acute brain and spinal cord trauma

Diffusion Tensor Imaging in Acute Spinal Cord Injury: A Review of Animal and Human Studies.

(Kaushal M, Shabani S, Budde M, Kurpad S.) J Neurotrauma. 2019 Aug 01;36(15):2279-2286 PMID: 30950317 SCOPUS ID: 2-s2.0-85071059121 04/06/2019
Repeated blast model of mild traumatic brain injury alters oxycodone self-administration and drug seeking.

(Nawarawong NN, Slaker M, Muelbl M, Shah AS, Chiariello R, Nelson LD, Budde MD, Stemper BD, Olsen CM.) Eur J Neurosci. 2019 Aug;50(3):2101-2112 PMID: 30456793 PMCID: PMC6814147 SCOPUS ID: 2-s2.0-85058419226 11/21/2018
Comparison between quantitative measurements of diffusion tensor imaging and T2 signal intensity in a large series of cervical spondylotic myelopathy patients for assessment of disease severity and prognostication of recovery.

(Shabani S, Kaushal M, Budde M, Schmit B, Wang MC, Kurpad S.) J Neurosurg Spine. 2019 Jun 07:1-7 PMID: 31174184 SCOPUS ID: 2-s2.0-85072775711 06/08/2019
In vivo high-resolution diffusion tensor imaging of the developing neonatal rat cortex and its relationship to glial and dendritic maturation.

(Breu M, Reisinger D, Tao L, Wu D, Zhang Y, Budde MD, Fatemi A, Pathak AP, Zhang J.) Brain Struct Funct. 2019 Jun;224(5):1815-1829 PMID: 31011813 PMCID: PMC6565480 SCOPUS ID: 2-s2.0-85064609350 04/24/2019
Longitudinal Diffusion Magnetic Resonance Imaging Remote from the Lesion Site in Rat Spinal Cord Injury.

(Motovylyak A, Skinner NP, Schmit BD, Wilkins N, Kurpad SN, Budde MD.) J Neurotrauma. 2019 May 01;36(9):1389-1398 PMID: 30259800 PMCID: PMC6482909 SCOPUS ID: 2-s2.0-85065073949 09/28/2018
Correlation of magnetic resonance diffusion tensor imaging parameters with American Spinal Injury Association score for prognostication and long-term outcomes.

(Shabani S, Kaushal M, Budde M, Kurpad SN.) Neurosurg Focus. 2019 03 01;46(3):E2 PMID: 30835673 SCOPUS ID: 2-s2.0-85062643112 03/06/2019
Effects of Mild Blast Traumatic Brain Injury on Cognitive- and Addiction-Related Behaviors.

(Muelbl MJ, Slaker ML, Shah AS, Nawarawong NN, Gerndt CH, Budde MD, Stemper BD, Olsen CM.) Sci Rep. 2018 07 02;8(1):9941 PMID: 29967344 PMCID: PMC6028456 SCOPUS ID: 2-s2.0-85049369592 07/04/2018
Diffusion MRI in acute nervous system injury.

(Budde MD, Skinner NP.) J Magn Reson. 2018 07;292:137-148 PMID: 29773299 SCOPUS ID: 2-s2.0-85047209748 05/19/2018
Filter-probe diffusion imaging improves spinal cord injury outcome prediction.

(Skinner NP, Lee SY, Kurpad SN, Schmit BD, Muftuler LT, Budde MD.) Ann Neurol. 2018 07;84(1):37-50 PMID: 29752739 PMCID: PMC6119508 SCOPUS ID: 2-s2.0-85050866980 05/13/2018
Design and validation of diffusion MRI models of white matter.

(Jelescu IO, Budde MD.) Front Phys. 2017 11;28 PMID: 29755979 PMCID: PMC5947881 05/15/2018
Multispectral diffusion-weighted MRI of the instrumented cervical spinal cord: a preliminary study of 5 cases.

(Koch KM, Bhave S, Kaushik SS, Nencka AS, Budde MD.) Eur Spine J. 2019 Dec 12 PMID: 31832875 SCOPUS ID: 2-s2.0-85076835282 12/14/2019
Evolution of MRI as Predictors and Correlates of Functional Outcome After Spinal Cord Contusion Injury in the Rat.

(Wilkins NL, Skinner NP, Motovylyak A, Schmit BD, Kurpad SN, Budde MD.) J Neurotrauma. 2019 Dec 13 PMID: 31830856 12/14/2019

Matthew D. Budde, PhD