Matthew D. Budde, PhD

Associate Professor

Locations

Neurosurgery
8701 Watertown Plank Rd.
Milwaukee, WI 53226

Education

BS, Psychology, University of Wisconsin, Madison, WI, 2001
PhD, Neuroscience, Washington University, St Louis, MO, 2008
Postdoctoral Fellow, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 2011

Biography

Dr. Matthew Budde is an Associate Professor of Neurosurgery at the Medical College of Wisconsin. He received his PhD in Neuroscience from Washington University in St. Louis in 2008. He completed his postdoctoral training at the National Institutes of Health in Bethesda, MD and was a recipient of the Fellows Award for Research Excellence in 2011.

Dr. Budde’s primary research interest is to develop and employ magnetic resonance imaging techniques to diagnosis and monitor injuries and diseases of the central nervous system. He has made significant contributions to the field and has over 20 peer-reviewed publications. He is an active member and Junior Fellow of the International Society for Magnetic Resonance in Medicine and a member of the Society for Neuroscience.

Honors and Awards

05/2006 – Young Investigator Award Finalist, International Society for Magnetic Resonance in Medicine
05/2010 – Junior Fellow Recipient, International Society for Magnetic Resonance in Medicine
02/2011 – Fellows Award for Research Excellence (FARE), National Institutes of Health, Bethesda, National Institutes of Health

Research Experience

Brain Concussion
Brain Injuries
Diffuse Axonal Injury
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging
Disease Models, Animal
Histology
Hypoxia-Ischemia, Brain
Magnetic Resonance Imaging
Microscopy
Multiple Sclerosis
Neurosciences

MCW Program / Core Facilities

Center for Imaging Research
Neuroscience Research Center

Research Interests

Development and application of magnetic resonance imaging techniques to diagnose and monitor brain and spinal cord injury.

Apply advanced MRI techniques, including diffusion tensor imaging (DTI), to detect and monitor injury to the central nervous system noninvasively
Define the specific biological features that give rise to the MRI findings using animal models of neurological injury
Determine the prognostic capabilities of MRI in acute brain and spinal cord trauma

Diffusion Tensor Imaging in Acute Spinal Cord Injury: A Review of Animal and Human Studies.

(Kaushal M, Shabani S, Budde M, Kurpad S.) J Neurotrauma. 2019 Aug 01;36(15):2279-2286.
Repeated blast model of mild traumatic brain injury alters oxycodone self-administration and drug seeking.

(Nawarawong NN, Slaker M, Muelbl M, Shah AS, Chiariello R, Nelson LD, Budde MD, Stemper BD, Olsen CM.) Eur J Neurosci. 2019 Aug;50(3):2101-2112.
Comparison between quantitative measurements of diffusion tensor imaging and T2 signal intensity in a large series of cervical spondylotic myelopathy patients for assessment of disease severity and prognostication of recovery.

(Shabani S, Kaushal M, Budde M, Schmit B, Wang MC, Kurpad S.) J Neurosurg Spine. 2019 Jun 07:1-7.
In vivo high-resolution diffusion tensor imaging of the developing neonatal rat cortex and its relationship to glial and dendritic maturation.

(Breu M, Reisinger D, Tao L, Wu D, Zhang Y, Budde MD, Fatemi A, Pathak AP, Zhang J.) Brain Struct Funct. 2019 Jun;224(5):1815-1829.
Longitudinal Diffusion Magnetic Resonance Imaging Remote from the Lesion Site in Rat Spinal Cord Injury.

(Motovylyak A, Skinner NP, Schmit BD, Wilkins N, Kurpad SN, Budde MD.) J Neurotrauma. 2019 May 01;36(9):1389-1398.
Correlation of magnetic resonance diffusion tensor imaging parameters with American Spinal Injury Association score for prognostication and long-term outcomes.

(Shabani S, Kaushal M, Budde M, Kurpad SN.) Neurosurg Focus. 2019 03 01;46(3):E2.
Diffusion Tensor Imaging in a Large Longitudinal Series of Patients With Cervical Spondylotic Myelopathy Correlated With Long-Term Functional Outcome.

(Rao A, Soliman H, Kaushal M, Motovylyak O, Vedantam A, Budde MD, Schmit B, Wang M, Kurpad SN.) Neurosurgery. 2018 10 01;83(4):753-760.
Effects of Mild Blast Traumatic Brain Injury on Cognitive- and Addiction-Related Behaviors.

(Muelbl MJ, Slaker ML, Shah AS, Nawarawong NN, Gerndt CH, Budde MD, Stemper BD, Olsen CM.) Sci Rep. 2018 07 02;8(1):9941.
Diffusion MRI in acute nervous system injury.

(Budde MD, Skinner NP.) J Magn Reson. 2018 07;292:137-148.
Filter-probe diffusion imaging improves spinal cord injury outcome prediction.

(Skinner NP, Lee SY, Kurpad SN, Schmit BD, Muftuler LT, Budde MD.) Ann Neurol. 2018 07;84(1):37-50.
Design and validation of diffusion MRI models of white matter.

(Jelescu IO, Budde MD.) Front Phys. 2017 11;28.
Optimizing Filter-Probe Diffusion Weighting in the Rat Spinal Cord for Human Translation.

(Budde MD, Skinner NP, Muftuler LT, Schmit BD, Kurpad SN.) Front Neurosci. 2017;11:706.

Matthew D. Budde, PhD