Matthew D. Budde, PhD

Associate Professor

Locations

Neurosurgery
8701 Watertown Plank Rd.
Milwaukee, WI 53226

Education

BS, Psychology, University of Wisconsin, Madison, WI, 2001
PhD, Neuroscience, Washington University, St Louis, MO, 2008
Postdoctoral Fellow, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, 2011

Biography

Dr. Matthew Budde is an Associate Professor of Neurosurgery at the Medical College of Wisconsin. He received his PhD in Neuroscience from Washington University in St. Louis in 2008. He completed his postdoctoral training at the National Institutes of Health in Bethesda, MD and was a recipient of the Fellows Award for Research Excellence in 2011.

Dr. Budde’s primary research interest is to develop and employ magnetic resonance imaging techniques to diagnosis and monitor injuries and diseases of the central nervous system. He has made significant contributions to the field and has over 20 peer-reviewed publications. He is an active member and Junior Fellow of the International Society for Magnetic Resonance in Medicine and a member of the Society for Neuroscience.

Honors and Awards

05/2006 – Young Investigator Award Finalist, International Society for Magnetic Resonance in Medicine
05/2010 – Junior Fellow Recipient, International Society for Magnetic Resonance in Medicine
02/2011 – Fellows Award for Research Excellence (FARE), National Institutes of Health, Bethesda, National Institutes of Health

Research Experience

Brain Concussion
Brain Injuries
Diffuse Axonal Injury
Diffusion Magnetic Resonance Imaging
Diffusion Tensor Imaging
Disease Models, Animal
Histology
Hypoxia-Ischemia, Brain
Magnetic Resonance Imaging
Microscopy
Multiple Sclerosis
Neurosciences

MCW Program / Core Facilities

Center for Imaging Research
Neuroscience Research Center

Research Interests

Development and application of magnetic resonance imaging techniques to diagnose and monitor brain and spinal cord injury.

Apply advanced MRI techniques, including diffusion tensor imaging (DTI), to detect and monitor injury to the central nervous system noninvasively
Define the specific biological features that give rise to the MRI findings using animal models of neurological injury
Determine the prognostic capabilities of MRI in acute brain and spinal cord trauma

Association of Head Impact Exposure with White Matter Macrostructure and Microstructure Metrics.

(Brett BL, Koch KM, Muftuler LT, Budde M, McCrea MA, Meier TB.) J Neurotrauma. 2020 Nov 10 PMID: 33003979 10/03/2020
Optimized cardiac functional MRI of small-animal models of cancer radiation therapy.

(Ibrahim EH, Baruah D, Budde M, Rubenstein J, Frei A, Schlaak R, Gore E, Bergom C.) Magn Reson Imaging. 2020 11;73:130-137 PMID: 32866598 PMCID: PMC7530081 SCOPUS ID: 2-s2.0-85090239163 09/01/2020
Diffusion tensor distribution imaging of an in vivo mouse brain at ultrahigh magnetic field by spatiotemporal encoding.

(Yon M, de Almeida Martins JP, Bao Q, Budde MD, Frydman L, Topgaard D.) NMR Biomed. 2020 Nov;33(11):e4355 PMID: 32812669 PMCID: PMC7583469 SCOPUS ID: 2-s2.0-85089471271 08/20/2020
Serial Diffusion Kurtosis Magnetic Resonance Imaging Study during Acute, Subacute, and Recovery Periods after Sport-Related Concussion.

(Muftuler LT, Meier TB, Keith M, Budde MD, Huber DL, McCrea MA.) J Neurotrauma. 2020 Oct 01;37(19):2081-2092 PMID: 32253977 SCOPUS ID: 2-s2.0-85092679959 04/08/2020
Multispectral diffusion-weighted MRI of the instrumented cervical spinal cord: a preliminary study of 5 cases.

(Koch KM, Bhave S, Kaushik SS, Nencka AS, Budde MD.) Eur Spine J. 2020 05;29(5):1071-1077 PMID: 31832875 PMCID: PMC7225051 SCOPUS ID: 2-s2.0-85076835282 12/14/2019
Evolution of Magnetic Resonance Imaging as Predictors and Correlates of Functional Outcome after Spinal Cord Contusion Injury in the Rat.

(Wilkins N, Skinner NP, Motovylyak A, Schmit BD, Kurpad S, Budde MD.) J Neurotrauma. 2020 03 15;37(6):889-898 PMID: 31830856 PMCID: PMC7071026 SCOPUS ID: 2-s2.0-85082509051 12/14/2019
Diffusion tensor imaging in cervical spondylotic myelopathy: a review.

(Shabani S, Kaushal M, Budde MD, Wang MC, Kurpad SN.) J Neurosurg Spine. 2020 Feb 28:1-8 PMID: 32109862 SCOPUS ID: 2-s2.0-85090702776 02/29/2020
Optimized Cervical Spinal Cord Perfusion MRI after Traumatic Injury in the Rat

(Meyer, BP., Hirschler, L., Lee, S., Kurpad, SN., Warnking, JM., Barbier, EL., and Budde, MD.) JCBFM. Accepted. 11/24/2020
Diffusion Tensor Imaging in Acute Spinal Cord Injury: A Review of Animal and Human Studies.

(Kaushal M, Shabani S, Budde M, Kurpad S.) J Neurotrauma. 2019 08 01;36(15):2279-2286 PMID: 30950317 SCOPUS ID: 2-s2.0-85071059121 04/06/2019
Comparison between quantitative measurements of diffusion tensor imaging and T2 signal intensity in a large series of cervical spondylotic myelopathy patients for assessment of disease severity and prognostication of recovery.

(Shabani S, Kaushal M, Budde M, Schmit B, Wang MC, Kurpad S.) J Neurosurg Spine. 2019 Jun 07:1-7 PMID: 31174184 SCOPUS ID: 2-s2.0-85072775711 06/08/2019
In vivo high-resolution diffusion tensor imaging of the developing neonatal rat cortex and its relationship to glial and dendritic maturation.

(Breu M, Reisinger D, Tao L, Wu D, Zhang Y, Budde MD, Fatemi A, Pathak AP, Zhang J.) Brain Struct Funct. 2019 Jun;224(5):1815-1829 PMID: 31011813 PMCID: PMC6565480 SCOPUS ID: 2-s2.0-85064609350 04/24/2019
Correlation of magnetic resonance diffusion tensor imaging parameters with American Spinal Injury Association score for prognostication and long-term outcomes.

(Shabani S, Kaushal M, Budde M, Kurpad SN.) Neurosurg Focus. 2019 03 01;46(3):E2 PMID: 30835673 SCOPUS ID: 2-s2.0-85062643112 03/06/2019

Matthew D. Budde, PhD