Jieqing Zhu, PhD

Publications

• The pivotal role of von Willebrand factor binding to platelet αIIbβ3 in stabilizing the formation of a platelet plug at sites of injury.

  (Shi Q, Mattson JG, Morateck PA, Christopherson PA, Schroeder JA, Fahs SA, Rapten J, Schulte ML, Weiler H, Zhu J, Haberichter SL, Flood VH, Montgomery RR.) Haematologica. 2025 Oct 01;110(10):2343-2355 PMID: 40400463 PMCID: PMC12485351 SCOPUS ID: 2-s2.0-105017783600 05/22/2025

• Oxidized LDL stimulates PKM2-mediated mtROS production and phagocytosis.

  (Zhang J, Chang J, Chen V, Beg MA, Huang W, Vick L, Wang Y, Zhang H, Yttre E, Gupta A, Castleberry M, Zhang Z, Dai W, Zhu J, Song S, Yang M, Brown AK, Xu Z, Ma YQ, Smith BC, Zielonka J, Traylor JG Jr, Ben Dhaou C, Orr AW, Cui W, Chen Y.) J Lipid Res. 2025 May;66(5):100809 PMID: 40250804 PMCID: PMC12142535 SCOPUS ID: 2-s2.0-105006766220 04/19/2025

• Luminescent sensing of conformational integrin activation in living cells.

  (Villari G, Gioelli N, Gino M, Zhang H, Hodge K, Cordero F, Zanivan S, Zhu J, Serini G.) Cell Rep. 2025 Feb 25;44(2):115319 PMID: 39964812 PMCID: PMC11861568 02/18/2025

• Prothrombotic antibodies targeting the spike protein's receptor-binding domain in severe COVID-19.

  (Zhu W, Zheng Y, Yu M, Witman N, Zhou L, Wei J, Zhang Y, Topchyan P, Nguyen C, Wang D, Janecke R, Padmanabhan A, Baumann Kreuziger L, White GC, Hari P, Gu T, Fields AT, Kornblith LZ, Aster R, Zhu J, Cui W, Jobe S, Graham MB, Wang D, Wen R.) Blood. 2025 Feb 06;145(6):635-647 PMID: 39576992 PMCID: PMC11811936 SCOPUS ID: 2-s2.0-85214228692 11/22/2024

• Facilitating and restraining virus infection using cell-attachable soluble viral receptors.

  (Zhang H, Wang Z, Nguyen HTT, Cornejo Pontelli M, Qi W, Rao L, Liu Z, Whelan SPJ, Zhu J.) Proc Natl Acad Sci U S A. 2024 Nov 05;121(45):e2414583121 PMID: 39480852 PMCID: PMC11551432 11/04/2024

• Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway.

  (Zhang J, Chang J, Chen V, Beg MA, Huang W, Vick L, Wang Y, Zhang H, Yttre E, Gupta A, Castleberry M, Zhang Z, Dai W, Song S, Zhu J, Yang M, Brown AK, Xu Z, Ma YQ, Smith BC, Zielonka J, Traylor JG, Dhaou CB, Orr AW, Cui W, Zheng Z, Chen Y.) bioRxiv. 2024 Jul 15 PMID: 39071358 PMCID: PMC11275753 07/29/2024

• Borrelia burgdorferi tolerates alteration to P66 porin function in a murine infectivity model.

  (Fierros CH, Faucillion ML, Hahn BL, Anderson P, Bonde M, Kessler JR, Surdel MC, Crawford KS, Gao Y, Zhu J, Bergström S, Coburn J.) Front Cell Infect Microbiol. 2024;14:1528456 PMID: 39906208 PMCID: PMC11790652 SCOPUS ID: 2-s2.0-85216789061 02/05/2025

• Integrin α5β1 contributes to cell fusion and inflammation mediated by SARS-CoV-2 spike via RGD-independent interaction.

  (Zhang H, Wang Z, Nguyen HTT, Watson AJ, Lao Q, Li A, Zhu J.) Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2311913120 PMID: 38060559 PMCID: PMC10723138 12/07/2023

• Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes.

  (Dai W, Zhang H, Lund H, Zhang Z, Castleberry M, Rodriguez M, Kuriakose G, Gupta S, Lewandowska M, Powers HR, Valmiki S, Zhu J, Shapiro AD, Hussain MM, López JA, Sorci-Thomas MG, Silverstein RL, Ginsberg HN, Sahoo D, Tabas I, Zheng Z.) Science. 2023 Sep;381(6661):eadh5207 PMID: 37651538 PMCID: PMC10697821 SCOPUS ID: 2-s2.0-85169348601 08/31/2023

• A single F153Sβ3 mutation causes constitutive integrin αIIbβ3 activation in a variant form of Glanzmann thrombasthenia.

  (Koukouritaki SB, Thinn AMM, Ashworth KJ, Fang J, Slater HS, Du LM, Nguyen HTT, Pillois X, Nurden AT, Ng CJ, Di Paola J, Zhu J, Wilcox DA.) Blood Adv. 2023 Jul 11;7(13):3180-3191 PMID: 36884296 PMCID: PMC10338211 SCOPUS ID: 2-s2.0-85179497686 03/09/2023

• Family-wide analysis of integrin structures predicted by AlphaFold2.

  (Zhang H, Zhu DS, Zhu J.) Comput Struct Biotechnol J. 2023;21:4497-4507 PMID: 37753178 PMCID: PMC10518446 09/27/2023