Francis Peterson, PhD

Publications

• Mechanistic Insight into the Suppression of Polyglutamine Aggregation by SRCP1.

  (Haver HN, Wedemeyer M, Butcher E, Peterson FC, Volkman BF, Scaglione KM.) ACS Chem Biol. 2023 Mar 17;18(3):549-560 PMID: 36791332 PMCID: PMC10023506 SCOPUS ID: 2-s2.0-85148304370 02/16/2023

• The Chemokine, CCL20, and Its Receptor, CCR6, in the Pathogenesis and Treatment of Psoriasis and Psoriatic Arthritis

  (Shi ZR, Mabuchi T, Riutta SJ, Wu X, Peterson FC, Volkman BF, Hwang ST.) Journal of Psoriasis and Psoriatic Arthritis. 2023 SCOPUS ID: 2-s2.0-85150743226 01/01/2023

• Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission.

  (Egner JM, Nolden KA, Harwig MC, Bonate RP, De Anda J, Tessmer MH, Noey EL, Ihenacho UK, Liu Z, Peterson FC, Wong GCL, Widlansky ME, Hill RB.) J Biol Chem. 2022 Dec;298(12):102620 PMID: 36272645 PMCID: PMC9747602 SCOPUS ID: 2-s2.0-85143990858 10/23/2022

• Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds.

  (Beltrán J, Steiner PJ, Bedewitz M, Wei S, Peterson FC, Li Z, Hughes BE, Hartley Z, Robertson NR, Medina-Cucurella AV, Baumer ZT, Leonard AC, Park SY, Volkman BF, Nusinow DA, Zhong W, Wheeldon I, Cutler SR, Whitehead TA.) Nat Biotechnol. 2022 Dec;40(12):1855-1861 PMID: 35726092 PMCID: PMC9750858 SCOPUS ID: 2-s2.0-85132543880 06/22/2022

• Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening.

  (Shishodia S, Nuñez R, Strohmier BP, Bursch KL, Goetz CJ, Olp MD, Jensen DR, Fenske TG, Ordonez-Rubiano SC, Blau ME, Roach MK, Peterson FC, Volkman BF, Dykhuizen EC, Smith BC.) J Med Chem. 2022 Oct 27;65(20):13714-13735 PMID: 36227159 PMCID: PMC9630929 SCOPUS ID: 2-s2.0-85140311972 10/14/2022

• Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor.

  (Kleist AB, Jenjak S, Sente A, Laskowski LJ, Szpakowska M, Calkins MM, Anderson EI, McNally LM, Heukers R, Bobkov V, Peterson FC, Thomas MA, Chevigné A, Smit MJ, McCorvy JD, Babu MM, Volkman BF.) Science. 2022 Jul 08;377(6602):222-228 PMID: 35857540 PMCID: PMC9574477 SCOPUS ID: 2-s2.0-85133822505 07/21/2022

• The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist.

  (Berg C, Wedemeyer MJ, Melynis M, Schlimgen RR, Hansen LH, Våbenø J, Peterson FC, Volkman BF, Rosenkilde MM, Lüttichau HR.) PLoS Pathog. 2022 Mar;18(3):e1010355 PMID: 35271688 PMCID: PMC8939814 SCOPUS ID: 2-s2.0-85127373696 03/11/2022

• Structural Insights into Molecular Recognition by Human Chemokine CCL19.

  (Lewandowski EM, Kroeck KG, Jacobs LMC, Fenske TG, Witt RN, Hintz AM, Ramsden ER, Zhang X, Peterson F, Volkman BF, Veldkamp CT, Chen Y.) Biochemistry. 2022 Mar 01;61(5):311-318 PMID: 35156805 PMCID: PMC9254573 SCOPUS ID: 2-s2.0-85125310513 02/15/2022

• Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic Tails.

  (Brandum EP, Jørgensen AS, Calvo MB, Spiess K, Peterson FC, Yang Z, Volkman BF, Veldkamp CT, Rosenkilde MM, Goth CK, Hjortø GM.) Int J Mol Sci. 2022 Jan 26;23(3) PMID: 35163323 PMCID: PMC8836243 02/16/2022

• Fluorinated triphenylphosphonium analogs improve cell selectivity and in vivo detection of mito-metformin

  (AbuEid M, Keyes RF, McAllister D, Peterson F, Kadamberi IP, Sprague DJ, Chaluvally-Raghavan P, Smith BC, Dwinell MB.) iScience. 22 December 2022;25(12) SCOPUS ID: 2-s2.0-85143723525 12/22/2022

• Conformational selection guides β-arrestin recruitment at a biased G protein–coupled receptor

  (Kleist AB, Jenjak S, Sente A, Laskowski LJ, Szpakowska M, Calkins MM, Anderson EI, McNally LM, Heukers R, Bobkov V, Peterson FC, Thomas MA, Chevigné A, Smit MJ, McCorvy JD, Babu MM, Volkman BF.) Science. 8 July 2022;377(6602):222-228 SCOPUS ID: 2-s2.0-85133822505 07/08/2022

• Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic Tails

  (Brandum EP, Jørgensen AS, Calvo MB, Spiess K, Peterson FC, Yang Z, Volkman BF, Veldkamp CT, Rosenkilde MM, Goth CK, Hjortø GM.) International Journal of Molecular Sciences. February-1 2022;23(3) SCOPUS ID: 2-s2.0-85123296293 02/01/2022