Victor X. Jin, PhD
Linda T. and John A. Mellowes Endowed Chair of Bioinformatics and Data Analytics; Professor, IHE/Biostatistics
Locations
- Biostatistics
8701 Watertown Plank Rd.
HRC-H5145 (office)
Milwaukee, WI 53226
Contact Information
Research Areas of Interest
- 1) Developing genomics and computational approaches for the identification of three-dimensional (3D) chromatin interactions from the various omics-seq data.
- 2) Functionally and mechanistically characterizing the roles of epigenetic marks in cancer development and progression using novel techniques such as 3C/ChIP/RT-qPCR, 3D-FISH and CRISPR/Cas9.
- 3) Adapting/applying genome-wide omics-seq techniques in patient tissues to identify epigenetic-driven therapeutic targets and biomarkers.
Research Experience
- Dr. Jin has extensive experience in developing computational and genomics approaches for analyzing various omics-seq data, and runs a systems biology lab with a balanced dry and wet components.
Leadership Positions
- Associate Director of Bioinformatics and Systems Biology, Mellowes Center for Genomic Sciences and Precision Medicine
- Director, Bioinformatics Shared Resources
Publications
-
(Chimge NO, Chen MH, Nguyen C, Zhao Y, Wu X, Gonzalez PG, Ogana H, Hurwitz S, Teo JL, Chen X, Du J, Jin V, Kim YM, Ono M, Argüello RJ, Kahn M.) Curr Mol Pharmacol. 2024;17(1):e060923220758 PMID: 37691195 09/11/2023
-
(Zhou Y, Li T, He Z, Choppavarapu L, Hu X, Cao R, Leone GW, Kahn M, Jin VX.) bioRxiv. 2023 Nov 14 PMID: 38013997 PMCID: PMC10680786 11/28/2023
-
An essential signaling function of cytoplasmic NELFB is independent of RNA polymerase II pausing.
(Pan H, Cheng X, Rodríguez PFG, Zhang X, Chung I, Jin VX, Li W, Hu Y, Li R.) J Biol Chem. 2023 Nov;299(11):105259 PMID: 37717699 PMCID: PMC10591015 09/18/2023
-
(Zhou Y, Li T, Choppavarapu L, Jin VX.) bioRxiv. 2023 Oct 02 PMID: 37873257 PMCID: PMC10592853 10/24/2023
-
(Han L, Wu Y, Fang K, Sweeney S, Roesner UK, Parrish M, Patel K, Walter T, Piermattei J, Trimboli A, Lefler J, Timmers CD, Yu XZ, Jin VX, Zimmermann MT, Mathison AJ, Urrutia R, Ostrowski MC, Leone G.) Nat Commun. 2023 Jan 03;14(1):1 PMID: 36596776 PMCID: PMC9810714 SCOPUS ID: 2-s2.0-85145429848 01/04/2023
-
Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.
(Cui Z, Zeng C, Huang F, Yuan F, Yan J, Zhao Y, Zhou Y, Hankey W, Jin VX, Huang J, Staats HF, Everitt JI, Sempowski GD, Wang H, Dong Y, Liu SL, Wang Q.) Nat Chem Biol. 2022 Oct;18(10):1056-1064 PMID: 35879545 PMCID: PMC10082993 07/26/2022
-
Dynamic nucleosome landscape elicits a noncanonical GATA2 pioneer model.
(Li T, Liu Q, Chen Z, Fang K, Huang F, Fu X, Wang Q, Jin VX.) Nat Commun. 2022 Jun 07;13(1):3145 PMID: 35672415 PMCID: PMC9174260 06/08/2022
-
(Singla R, Mishra A, Lin H, Lorsung E, Le N, Tin S, Jin VX, Cao R.) Int J Mol Sci. 2022 Jun 05;23(11) PMID: 35682995 PMCID: PMC9181331 06/11/2022
-
(Xie Q, Han C, Jin V, Lin S.) PLoS Comput Biol. 2022 Jun;18(6):e1010129 PMID: 35696429 PMCID: PMC9232133 06/14/2022
-
Phosphorylated MED1 links transcription recycling and cancer growth.
(Chen Z, Ye Z, Soccio RE, Nakadai T, Hankey W, Zhao Y, Huang F, Yuan F, Wang H, Cui Z, Sunkel B, Wu D, Dzeng RK, Thomas-Ahner JM, Huang THM, Clinton SK, Huang J, Lazar MA, Jin VX, Roeder RG, Wang Q.) Nucleic Acids Res. 2022 May 06;50(8):4450-4463 PMID: 35394046 PMCID: PMC9071494 04/09/2022
-
(Shropshire DB, Acosta FM, Fang K, Benavides J, Sun LZ, Jin VX, Jiang JX.) Front Med (Lausanne). 2022;9:965429 PMID: 36186774 PMCID: PMC9520286 10/04/2022
-
Mapping nucleosome and chromatin architectures: A survey of computational methods.
(Fang K, Wang J, Liu L, Jin VX.) Comput Struct Biotechnol J. 2022;20:3955-3962 PMID: 35950186 PMCID: PMC9340519 08/12/2022