Olena Isaeva, PhD
Assistant Professor
Locations
- Cell Biology, Neurobiology & Anatomy
BSB4
Contact Information
Education
Postdoctoral, Rutgers New Jersey Medical School, Newark, NJ
Postdoctoral, Geisel School of Medicine at Dartmouth, Hanover, NH
Biography
Dr. Isaeva earned her PhD in Physiology at the Bogomoletz Institute of Physiology in Kyiv Ukraine. She had postdoctoral training in Dr. Natalia Shirokova’s laboratory in Rutgers New Jersey Medical School and the laboratory of Dr. Gregory L Holmes at Geisel School of Medicine at Dartmouth. In 2018 Dr. Isaeva joined the Physiology Department in Medical College of Wisconsin as Visiting Assistant Professor. She continues her career in the Department of Cell Biology, Neurobiology, and Anatomy, where she was promoted to Assistant Professor in 2021.
Research Areas of Interest
- Ion Channels
- Calcium Signaling
- Neuropathic Pain
- Epilepsy research
- Synaptic Physiology and Plasticity
- Behavioral Neuroscience
Methodologies and Techniques
- Single-Channel and Whole-Cell Patch Clamp
- Field Potential and Synaptic Plasticity
- EEG in Rodents
- Microscopy, Confocal
- Animal Behavior
- Cell Culture
- Immunolabeling
- Auditory Brain Response
- Transepithelial Current Measurement
Research Areas of Interest
- Calcium Signaling
- Epilepsy
- Hearing Disorders
- Hippocampus
- Hypertension
- Ion Channels
- Kidney
- Pain
- Sensation Disorders
Research Experience
- Behavior, Animal
- Electroencephalography
- Functional Neuroimaging
- Hearing Tests
- Patch-Clamp Techniques
Research Interests
Publications
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Protease-Activated Receptor 1-Mediated Damage of Podocytes in Diabetic Nephropathy.
(Bohovyk R, Khedr S, Levchenko V, Stefanenko M, Semenikhina M, Kravtsova O, Isaeva E, Geurts AM, Klemens CA, Palygin O, Staruschenko A.) Diabetes. 2023 Dec 01;72(12):1795-1808 PMID: 37722138 PMCID: PMC10658073 SCOPUS ID: 2-s2.0-85176576178 09/18/2023
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(Nikolaienko O, Klymenko M, Isaeva E.) Neurol Res. 2023 Dec;45(12):1152-1160 PMID: 37698124 SCOPUS ID: 2-s2.0-85170670600 09/12/2023
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Use the force, fluke: Ligand-independent gating of Schistosoma mansoni ion channel TRPMPZQ.
(Chulkov EG, Isaeva E, Stucky CL, Marchant JS.) Int J Parasitol. 2023 Jul;53(8):427-434 PMID: 36610555 PMCID: PMC10258140 SCOPUS ID: 2-s2.0-85146298174 01/08/2023
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(Polat OK, Isaeva E, Sudhini YR, Knott B, Zhu K, Noben M, Suresh Kumar V, Endlich N, Mangos S, Reddy TV, Samelko B, Wei C, Altintas MM, Dryer SE, Sever S, Staruschenko A, Reiser J.) Kidney Int. 2023 Jun;103(6):1056-1062 PMID: 36750145 PMCID: PMC10200725 SCOPUS ID: 2-s2.0-85148731140 02/08/2023
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Schwann cell release of p11 induces sensory neuron hyperactivity in Fabry disease.
(Waltz TB, Chao D, Prodoehl EK, Ehlers VL, Dharanikota BS, Dahms NM, Isaeva E, Hogan QH, Pan B, Stucky CL.) bioRxiv. 2023 May 28 PMID: 37292928 PMCID: PMC10245981 06/09/2023
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Spinal muscular atrophy-like phenotype in a mouse model of acid ceramidase deficiency.
(Nagree MS, Rybova J, Kleynerman A, Ahrenhoerster CJ, Saville JT, Xu T, Bachochin M, McKillop WM, Lawlor MW, Pshezhetsky AV, Isaeva O, Budde MD, Fuller M, Medin JA.) Commun Biol. 2023 May 25;6(1):560 PMID: 37231125 PMCID: PMC10212955 SCOPUS ID: 2-s2.0-85160222255 05/26/2023
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(Savotchenko AV, Isaeva EV, Isaev DS.) Biopolymers and Cell. 2023;39(2):146-151 SCOPUS ID: 2-s2.0-85166955495 01/01/2023
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(Savotchenko AV, Isaeva EV, Isaev DS.) Fiziologichnyi Zhurnal. 2023;69(4):40-44 SCOPUS ID: 2-s2.0-85169801582 01/01/2023
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(Xu B, Nikolaienko O, Levchenko V, Choubey AS, Isaeva E, Staruschenko A, Palygin O.) Physiol Rep. 2022 Nov;10(21):e15510 PMID: 36353932 PMCID: PMC9647406 SCOPUS ID: 2-s2.0-85141519233 11/11/2022
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Keratinocyte PIEZO1 modulates cutaneous mechanosensation.
(Mikesell AR, Isaeva O, Moehring F, Sadler KE, Menzel AD, Stucky CL.) Elife. 2022 Sep 02;11 PMID: 36053009 PMCID: PMC9512397 SCOPUS ID: 2-s2.0-85139375441 09/03/2022
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(Garvin J, Semenikhina M, Liu Q, Rarick K, Isaeva E, Levchenko V, Staruschenko A, Palygin O, Harder D, Cohen S.) Am J Physiol Regul Integr Comp Physiol. 2022 Jun 01;322(6):R571-R580 PMID: 35412389 PMCID: PMC9109795 SCOPUS ID: 2-s2.0-85130004068 04/13/2022
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(McClenahan SJ, Kent CN, Kharade SV, Isaeva E, Williams JC, Han C, Terker A, Gresham R 3rd, Lazarenko RM, Days EL, Romaine IM, Bauer JA, Boutaud O, Sulikowski GA, Harris R, Weaver CD, Staruschenko A, Lindsley CW, Denton JS.) Mol Pharmacol. 2022 May;101(5):357-370 PMID: 35246480 PMCID: PMC9092466 SCOPUS ID: 2-s2.0-85128248706 03/06/2022