Janet Sue Rader, MD, FACOG

Publications

• Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation.

  (Porter VL, Ng M, O'Neill K, MacLennan S, Corbett RD, Culibrk L, Hamadeh Z, Iden M, Schmidt R, Tsaih SW, Nakisige C, Origa M, Orem J, Chang G, Fan J, Nip KM, Akbari V, Chan SK, Hopkins J, Moore RA, Chuah E, Mungall KL, Mungall AJ, Birol I, Jones SJM, Rader JS, Marra MA.) Genome Res. 2025 Apr 14;35(4):653-670 PMID: 39638560 SCOPUS ID: 2-s2.0-105002734241 12/06/2024

• Immunohistochemistry in the Differential Diagnosis of Triple Negative Breast Carcinoma and High-grade Serous Carcinoma: Old and New Markers.

  (Jain PV, Molina M, Moh M, Bishop E, Rader JS, Jorns JM.) Appl Immunohistochem Mol Morphol. 2024 Nov-Dec 01;32(10):456-461 PMID: 39506288 SCOPUS ID: 2-s2.0-85208688860 11/12/2024

• Clinicopathologic Characteristics of a Single-institution Cohort of Ovarian Adult Granulosa Cell Tumors, With Biomarker and Therapeutic Implications Utilizing the Detection of Androgen, Estrogen, and Progesterone Hormone Receptor Expression by Immunohistochemistry.

  (Moh M, Puzyrenko A, Summey R, Rader JS, Herrera Cano GE, Gavina JV, Rui H, Sun Y, Hopp E.) Int J Gynecol Pathol. 2024 Sep 01;43(5):527-534 PMID: 38661526 SCOPUS ID: 2-s2.0-85201753022 04/25/2024

• Landscape of potential germline pathogenic variants in select cancer susceptibility genes in patients with adult-type ovarian granulosa cell tumors.

  (Summey RM, Gornstein E, Decker B, Dougherty KC, Rader JS, Hopp E.) Cancer Med. 2024 Jun;13(12):e7340 PMID: 38898688 PMCID: PMC11187164 SCOPUS ID: 2-s2.0-85196521716 06/20/2024

• Deciphering the divergent transcriptomic landscapes of cervical cancer cells grown in 3D and 2D cell culture systems.

  (Kumar R, Iden M, Tsaih SW, Schmidt R, Ojesina AI, Rader JS.) Front Cell Dev Biol. 2024;12:1413882 PMID: 39193365 PMCID: PMC11347336 08/28/2024

• Carboplatin, paclitaxel, and pembrolizumab followed by pembrolizumab maintenance for primary treatment of incompletely resected epithelial ovarian cancer.

  (Uyar D, Michener CM, Bishop E, Hopp E, Simpson P, Zhang L, Rader JS, Rose PG, Mahdi HS, Debernardo R, Christian Q, Bradley W.) Front Oncol. 2024;14:1291090 PMID: 38410102 PMCID: PMC10894939 02/27/2024

• Carboplatin, paclitaxel, and pembrolizumab followed by pembrolizumab maintenance for primary treatment of incompletely resected epithelial ovarian cancer

  (Uyar D, Michener CM, Bishop E, Hopp E, Simpson P, Zhang L, Rader JS, Rose PG, Mahdi HS, Debernardo R, Christian Q, Bradley W.) Frontiers in Oncology. 2024;14 SCOPUS ID: 2-s2.0-85186485797 01/01/2024

• Genomic structures and regulation patterns at HPV integration sites in cervical cancer.

  (Porter VL, O'Neill K, MacLennan S, Corbett RD, Ng M, Culibrk L, Hamadeh Z, Iden M, Schmidt R, Tsaih SW, Chang G, Fan J, Nip KM, Akbari V, Chan SK, Hopkins J, Moore RA, Chuah E, Mungall KL, Mungall AJ, Birol I, Jones SJM, Rader JS, Marra MA.) bioRxiv. 2023 Nov 05 PMID: 37961641 PMCID: PMC10635144 11/14/2023

• A Phase Ib Study Assessing the Safety, Tolerability, and Efficacy of the First-in-Class Wee1 Inhibitor Adavosertib (AZD1775) as Monotherapy in Patients with Advanced Solid Tumors.

  (Bauer TM, Moore KN, Rader JS, Simpkins F, Mita AC, Beck JT, Hart L, Chu Q, Oza A, Tinker AV, Imedio ER, Kumar S, Mugundu G, Jenkins S, Chmielecki J, Jones S, Spigel D, Fu S.) Target Oncol. 2023 Jul;18(4):517-530 PMID: 37278879 PMCID: PMC10345044 SCOPUS ID: 2-s2.0-85161298600 06/06/2023

• Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.

  (Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, Dentro SC, Blanco MG, Contino G, Ardeljan D, Tojo M, Roberts ND, Zumalave S, Edwards PA, Weischenfeldt J, Puiggròs M, Chong Z, Chen K, Lee EA, Wala JA, Raine KM, Butler A, Waszak SM, Navarro FCP, Schumacher SE, Monlong J, Maura F, Bolli N, Bourque G, Gerstein M, Park PJ, Wedge DC, Beroukhim R, Torrents D, Korbel JO, Martincorena I, Fitzgerald RC, Van Loo P, Kazazian HH, Burns KH, PCAWG Structural Variation Working Group, Campbell PJ, Tubio JMC, PCAWG Consortium.) Nat Genet. 2023 Jun;55(6):1080 PMID: 36944736 PMCID: PMC10260396 SCOPUS ID: 2-s2.0-85163260191 03/23/2023

• Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer.

  (Akdemir KC, Le VT, Chandran S, Li Y, Verhaak RG, Beroukhim R, Campbell PJ, Chin L, Dixon JR, Futreal PA, PCAWG Structural Variation Working Group, PCAWG Consortium.) Nat Genet. 2023 Jun;55(6):1079 PMID: 36944735 PMCID: PMC10260394 SCOPUS ID: 2-s2.0-85163256928 03/23/2023

• Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes.

  (Yakneen S, Waszak SM, PCAWG Technical Working Group, Gertz M, Korbel JO, PCAWG Consortium.) Nat Biotechnol. 2023 Apr;41(4):577 PMID: 36944844 PMCID: PMC10110458 SCOPUS ID: 2-s2.0-85152619137 03/23/2023